(18 nodes) MyD88-dependent toll-like receptor signaling pathway, and Protein unc-93 homolog B1 network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108902352	TIR domain-containing protein. (821 aa)
	ENSLCAP00010001624	TIR domain-containing protein. (808 aa)
	ENSLCAP00010001694	TIR domain-containing protein. (162 aa)
	ENSLCAP00010005490	Toll-like receptor 1; Belongs to the Toll-like receptor family. (811 aa)
	LOC108883170	TIR domain-containing protein. (878 aa)
	LOC108895804	TIR domain-containing protein; Belongs to the Toll-like receptor family. (890 aa)
	TLR8	Toll like receptor 8. (1037 aa)
	ENSLCAP00010013353	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1047 aa)
	ENSLCAP00010014608	TIR domain-containing protein. (165 aa)
	LOC108900141	Uncharacterized protein. (634 aa)
	LOC108888912	Uncharacterized protein. (486 aa)
	traf4	TNF receptor-associated factor. (470 aa)
	ENSLCAP00010026394	Sterile alpha and TIR motif containing 1. (675 aa)
	LOC108885749	Uncharacterized protein. (634 aa)
	TLR2	Toll like receptor 2. (689 aa)
	ENSLCAP00010049495	TIR domain-containing protein. (857 aa)
	ENSLCAP00010049506	TIR domain-containing protein. (641 aa)
	LOC108885865	TIR domain-containing protein. (821 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLCAP00010001624	ENSLCAP00010001694	ENSLCAP00010001624	ENSLCAP00010001694	TIR domain-containing protein.	TIR domain-containing protein.	0.518
ENSLCAP00010001624	ENSLCAP00010005490	ENSLCAP00010001624	ENSLCAP00010005490	TIR domain-containing protein.	Toll-like receptor 1; Belongs to the Toll-like receptor family.	0.565
ENSLCAP00010001624	ENSLCAP00010014608	ENSLCAP00010001624	ENSLCAP00010014608	TIR domain-containing protein.	TIR domain-containing protein.	0.518
ENSLCAP00010001624	LOC108885749	ENSLCAP00010001624	ENSLCAP00010037377	TIR domain-containing protein.	Uncharacterized protein.	0.424
ENSLCAP00010001624	LOC108900141	ENSLCAP00010001624	ENSLCAP00010025480	TIR domain-containing protein.	Uncharacterized protein.	0.424
ENSLCAP00010001694	ENSLCAP00010001624	ENSLCAP00010001694	ENSLCAP00010001624	TIR domain-containing protein.	TIR domain-containing protein.	0.518
ENSLCAP00010001694	LOC108885749	ENSLCAP00010001694	ENSLCAP00010037377	TIR domain-containing protein.	Uncharacterized protein.	0.419
ENSLCAP00010001694	LOC108885865	ENSLCAP00010001694	ENSLCAP00010049945	TIR domain-containing protein.	TIR domain-containing protein.	0.518
ENSLCAP00010001694	LOC108900141	ENSLCAP00010001694	ENSLCAP00010025480	TIR domain-containing protein.	Uncharacterized protein.	0.419
ENSLCAP00010001694	LOC108902352	ENSLCAP00010001694	ENSLCAP00010000854	TIR domain-containing protein.	TIR domain-containing protein.	0.518
ENSLCAP00010001694	TLR2	ENSLCAP00010001694	ENSLCAP00010041299	TIR domain-containing protein.	Toll like receptor 2.	0.518
ENSLCAP00010005490	ENSLCAP00010001624	ENSLCAP00010005490	ENSLCAP00010001624	Toll-like receptor 1; Belongs to the Toll-like receptor family.	TIR domain-containing protein.	0.565
ENSLCAP00010005490	LOC108883170	ENSLCAP00010005490	ENSLCAP00010009400	Toll-like receptor 1; Belongs to the Toll-like receptor family.	TIR domain-containing protein.	0.942
ENSLCAP00010005490	LOC108885749	ENSLCAP00010005490	ENSLCAP00010037377	Toll-like receptor 1; Belongs to the Toll-like receptor family.	Uncharacterized protein.	0.419
ENSLCAP00010005490	LOC108885865	ENSLCAP00010005490	ENSLCAP00010049945	Toll-like receptor 1; Belongs to the Toll-like receptor family.	TIR domain-containing protein.	0.974
ENSLCAP00010005490	LOC108888912	ENSLCAP00010005490	ENSLCAP00010025488	Toll-like receptor 1; Belongs to the Toll-like receptor family.	Uncharacterized protein.	0.611
ENSLCAP00010005490	LOC108895804	ENSLCAP00010005490	ENSLCAP00010013256	Toll-like receptor 1; Belongs to the Toll-like receptor family.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.430
ENSLCAP00010005490	LOC108900141	ENSLCAP00010005490	ENSLCAP00010025480	Toll-like receptor 1; Belongs to the Toll-like receptor family.	Uncharacterized protein.	0.419
ENSLCAP00010005490	LOC108902352	ENSLCAP00010005490	ENSLCAP00010000854	Toll-like receptor 1; Belongs to the Toll-like receptor family.	TIR domain-containing protein.	0.974
ENSLCAP00010005490	TLR2	ENSLCAP00010005490	ENSLCAP00010041299	Toll-like receptor 1; Belongs to the Toll-like receptor family.	Toll like receptor 2.	0.747