(24 nodes) Mixed, incl. Intrinsic component of mitochondrial outer membrane, and Synuclein network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLCAP00010010342	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (682 aa)
	LOC108874055	Uncharacterized protein; Belongs to the synuclein family. (127 aa)
	LOC108899379	Mab-21 domain-containing protein. (467 aa)
	sncb	Beta-synuclein; Belongs to the synuclein family. (135 aa)
	oma1	Peptidase_M48 domain-containing protein. (531 aa)
	Mfn2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (763 aa)
	ENSLCAP00010027714	Optic atrophy 1 (autosomal dominant); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (982 aa)
	ENSLCAP00010031904	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (459 aa)
	LOC108883510	Rhomboid domain-containing protein. (445 aa)
	pink1	Protein kinase domain-containing protein. (575 aa)
	Fundc1	Uncharacterized protein. (233 aa)
	SNCG	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family. (111 aa)
	ENSLCAP00010039671	Uncharacterized protein; Belongs to the synuclein family. (88 aa)
	pgam5	Uncharacterized protein. (302 aa)
	slc6a3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (618 aa)
	DNM1L	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (744 aa)
	LOC108895837	RING-CH-type domain-containing protein. (288 aa)
	Mfn1	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (759 aa)
	LOC108874357	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (463 aa)
	pink1-2	Serine/threonine-protein kinase PINK1, mitochondrial-like. (575 aa)
	LOC108890595	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (707 aa)
	ENSLCAP00010053657	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (637 aa)
	RHOT1	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (653 aa)
	ENSLCAP00010058311	Synuclein, alpha interacting protein. (871 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNM1L	ENSLCAP00010010342	ENSLCAP00010047000	ENSLCAP00010010342	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.454
DNM1L	ENSLCAP00010031904	ENSLCAP00010047000	ENSLCAP00010031904	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.627
DNM1L	LOC108874357	ENSLCAP00010047000	ENSLCAP00010048920	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.627
DNM1L	LOC108895837	ENSLCAP00010047000	ENSLCAP00010047682	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	RING-CH-type domain-containing protein.	0.455
DNM1L	LOC108899379	ENSLCAP00010047000	ENSLCAP00010015193	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mab-21 domain-containing protein.	0.757
DNM1L	Mfn1	ENSLCAP00010047000	ENSLCAP00010048878	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.454
DNM1L	Mfn2	ENSLCAP00010047000	ENSLCAP00010016537	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.454
DNM1L	oma1	ENSLCAP00010047000	ENSLCAP00010016094	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Peptidase_M48 domain-containing protein.	0.501
DNM1L	pgam5	ENSLCAP00010047000	ENSLCAP00010040099	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.439
DNM1L	pink1	ENSLCAP00010047000	ENSLCAP00010035987	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Protein kinase domain-containing protein.	0.619
DNM1L	pink1-2	ENSLCAP00010047000	ENSLCAP00010052377	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Serine/threonine-protein kinase PINK1, mitochondrial-like.	0.619
ENSLCAP00010010342	DNM1L	ENSLCAP00010010342	ENSLCAP00010047000	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.454
ENSLCAP00010010342	ENSLCAP00010027714	ENSLCAP00010010342	ENSLCAP00010027714	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Optic atrophy 1 (autosomal dominant); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.557
ENSLCAP00010010342	ENSLCAP00010031904	ENSLCAP00010010342	ENSLCAP00010031904	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.843
ENSLCAP00010010342	ENSLCAP00010053657	ENSLCAP00010010342	ENSLCAP00010053657	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.559
ENSLCAP00010010342	LOC108874357	ENSLCAP00010010342	ENSLCAP00010048920	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.983
ENSLCAP00010010342	LOC108890595	ENSLCAP00010010342	ENSLCAP00010053198	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.454
ENSLCAP00010010342	LOC108895837	ENSLCAP00010010342	ENSLCAP00010047682	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	RING-CH-type domain-containing protein.	0.533
ENSLCAP00010010342	LOC108899379	ENSLCAP00010010342	ENSLCAP00010015193	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mab-21 domain-containing protein.	0.507
ENSLCAP00010010342	Mfn1	ENSLCAP00010010342	ENSLCAP00010048878	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.901