(5 nodes) Cul4A-RING E3 ubiquitin ligase complex network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cul4a	Cullin 4A; Belongs to the cullin family. (751 aa)
	ENSLCAP00010029467	Damage-specific DNA binding protein 2. (366 aa)
	Ddb1	Damage-specific DNA binding protein 1. (1137 aa)
	dtl	WD_REPEATS_REGION domain-containing protein. (666 aa)
	ENSLCAP00010054323	Cullin 4B; Belongs to the cullin family. (916 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cul4a	Ddb1	ENSLCAP00010020892	ENSLCAP00010040539	Cullin 4A; Belongs to the cullin family.	Damage-specific DNA binding protein 1.	0.981
Cul4a	ENSLCAP00010029467	ENSLCAP00010020892	ENSLCAP00010029467	Cullin 4A; Belongs to the cullin family.	Damage-specific DNA binding protein 2.	0.935
Cul4a	ENSLCAP00010054323	ENSLCAP00010020892	ENSLCAP00010054323	Cullin 4A; Belongs to the cullin family.	Cullin 4B; Belongs to the cullin family.	0.917
Cul4a	dtl	ENSLCAP00010020892	ENSLCAP00010044877	Cullin 4A; Belongs to the cullin family.	WD_REPEATS_REGION domain-containing protein.	0.959
Ddb1	Cul4a	ENSLCAP00010040539	ENSLCAP00010020892	Damage-specific DNA binding protein 1.	Cullin 4A; Belongs to the cullin family.	0.981
Ddb1	ENSLCAP00010029467	ENSLCAP00010040539	ENSLCAP00010029467	Damage-specific DNA binding protein 1.	Damage-specific DNA binding protein 2.	0.999
Ddb1	ENSLCAP00010054323	ENSLCAP00010040539	ENSLCAP00010054323	Damage-specific DNA binding protein 1.	Cullin 4B; Belongs to the cullin family.	0.980
Ddb1	dtl	ENSLCAP00010040539	ENSLCAP00010044877	Damage-specific DNA binding protein 1.	WD_REPEATS_REGION domain-containing protein.	0.994
ENSLCAP00010029467	Cul4a	ENSLCAP00010029467	ENSLCAP00010020892	Damage-specific DNA binding protein 2.	Cullin 4A; Belongs to the cullin family.	0.935
ENSLCAP00010029467	Ddb1	ENSLCAP00010029467	ENSLCAP00010040539	Damage-specific DNA binding protein 2.	Damage-specific DNA binding protein 1.	0.999
ENSLCAP00010029467	ENSLCAP00010054323	ENSLCAP00010029467	ENSLCAP00010054323	Damage-specific DNA binding protein 2.	Cullin 4B; Belongs to the cullin family.	0.922
ENSLCAP00010029467	dtl	ENSLCAP00010029467	ENSLCAP00010044877	Damage-specific DNA binding protein 2.	WD_REPEATS_REGION domain-containing protein.	0.813
ENSLCAP00010054323	Cul4a	ENSLCAP00010054323	ENSLCAP00010020892	Cullin 4B; Belongs to the cullin family.	Cullin 4A; Belongs to the cullin family.	0.917
ENSLCAP00010054323	Ddb1	ENSLCAP00010054323	ENSLCAP00010040539	Cullin 4B; Belongs to the cullin family.	Damage-specific DNA binding protein 1.	0.980
ENSLCAP00010054323	ENSLCAP00010029467	ENSLCAP00010054323	ENSLCAP00010029467	Cullin 4B; Belongs to the cullin family.	Damage-specific DNA binding protein 2.	0.922
ENSLCAP00010054323	dtl	ENSLCAP00010054323	ENSLCAP00010044877	Cullin 4B; Belongs to the cullin family.	WD_REPEATS_REGION domain-containing protein.	0.959
dtl	Cul4a	ENSLCAP00010044877	ENSLCAP00010020892	WD_REPEATS_REGION domain-containing protein.	Cullin 4A; Belongs to the cullin family.	0.959
dtl	Ddb1	ENSLCAP00010044877	ENSLCAP00010040539	WD_REPEATS_REGION domain-containing protein.	Damage-specific DNA binding protein 1.	0.994
dtl	ENSLCAP00010029467	ENSLCAP00010044877	ENSLCAP00010029467	WD_REPEATS_REGION domain-containing protein.	Damage-specific DNA binding protein 2.	0.813
dtl	ENSLCAP00010054323	ENSLCAP00010044877	ENSLCAP00010054323	WD_REPEATS_REGION domain-containing protein.	Cullin 4B; Belongs to the cullin family.	0.959