(15 nodes) Blood vessel remodeling network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLCAP00010047727	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (458 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
	Rspo3	R-spondin 3. (307 aa)
	CRB2	Uncharacterized protein. (1470 aa)
	ENSLCAP00010025602	Autophagy protein 5; Involved in autophagic vesicle formation. (178 aa)
	LOC108880508	Uncharacterized protein. (205 aa)
	bax	Uncharacterized protein. (192 aa)
	Crb1	Uncharacterized protein. (990 aa)
	LOC108891182	Autophagy protein 5; Involved in autophagic vesicle formation. (314 aa)
	sema3c	Uncharacterized protein; Belongs to the semaphorin family. (766 aa)
	LOC108874243	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1262 aa)
	crb2	Uncharacterized protein. (1463 aa)
	ENSLCAP00010052465	Uncharacterized protein. (670 aa)
	EDNRA	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (474 aa)
	ENSLCAP00010041660	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (446 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMPR2	LOC108874243	ENSLCAP00010038004	ENSLCAP00010003400	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.901
EDNRA	ENSLCAP00010041660	ENSLCAP00010048555	ENSLCAP00010041660	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSLCAP00010041660	EDNRA	ENSLCAP00010041660	ENSLCAP00010048555	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.902
LOC108874243	BMPR2	ENSLCAP00010003400	ENSLCAP00010038004	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.901
LOC108880508	bax	ENSLCAP00010018028	ENSLCAP00010014364	Uncharacterized protein.	Uncharacterized protein.	0.989
bax	LOC108880508	ENSLCAP00010014364	ENSLCAP00010018028	Uncharacterized protein.	Uncharacterized protein.	0.989