(42 nodes) Regulation of glucose metabolic process network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fam3c	ILEI domain-containing protein. (227 aa)
	lcmt1	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (340 aa)
	Pdk1	Protein-serine/threonine kinase. (418 aa)
	ENSLCAP00010050425	Uncharacterized protein. (580 aa)
	ENSLCAP00010050148	RAN binding protein 2. (2922 aa)
	LOC108874357	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (463 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	LOC108885279	Uncharacterized protein. (616 aa)
	Ddb1	Damage-specific DNA binding protein 1. (1137 aa)
	Pdk4	Protein-serine/threonine kinase. (438 aa)
	bad	Uncharacterized protein. (229 aa)
	igf2	Insulin-like growth factor II. (215 aa)
	pth	Uncharacterized protein. (109 aa)
	sirt6	Deacetylase sirtuin-type domain-containing protein. (351 aa)
	ENSLCAP00010034576	Uncharacterized protein. (344 aa)
	ENSLCAP00010033942	Uncharacterized protein. (80 aa)
	Dusp12	Dual specificity phosphatase 12. (172 aa)
	SOGA1	Suppressor of glucose, autophagy associated 1. (1378 aa)
	LOC108874732	Uncharacterized protein. (260 aa)
	ENSLCAP00010031904	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (459 aa)
	ogt	TPR_REGION domain-containing protein. (1111 aa)
	LOC108892051	Protein-serine/threonine kinase. (409 aa)
	gnmt	Methyltranfer_dom domain-containing protein. (363 aa)
	LOC108875187	Uncharacterized protein. (161 aa)
	ENSLCAP00010023432	E1A binding protein p300 b. (2634 aa)
	Mlycd	Malonyl-CoA decarboxylase. (463 aa)
	IGFBP3	Uncharacterized protein. (295 aa)
	IGFBP4	Uncharacterized protein. (261 aa)
	Lepr	Leptin receptor. (1149 aa)
	Sirt1	Deacetylase sirtuin-type domain-containing protein. (705 aa)
	ENSLCAP00010014729	Forkhead box K1. (557 aa)
	DGKQ	Diacylglycerol kinase. (925 aa)
	LOC108874502	Uncharacterized protein. (617 aa)
	pdk3	Protein-serine/threonine kinase. (413 aa)
	sirt7	Deacetylase sirtuin-type domain-containing protein. (406 aa)
	ENSLCAP00010009959	Protein-serine/threonine kinase. (436 aa)
	ENSLCAP00010008624	Uncharacterized protein. (390 aa)
	Usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1202 aa)
	ENSLCAP00010006019	Midnolin. (501 aa)
	ENSLCAP00010005924	Diacylglycerol kinase. (714 aa)
	acadm	Uncharacterized protein. (424 aa)
	bckdk	Protein-serine/threonine kinase. (428 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ddb1	ENSLCAP00010023432	ENSLCAP00010040539	ENSLCAP00010023432	Damage-specific DNA binding protein 1.	E1A binding protein p300 b.	0.552
Ddb1	Sirt1	ENSLCAP00010040539	ENSLCAP00010015909	Damage-specific DNA binding protein 1.	Deacetylase sirtuin-type domain-containing protein.	0.446
Ddb1	Usp7	ENSLCAP00010040539	ENSLCAP00010007355	Damage-specific DNA binding protein 1.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.616
Ddb1	sirt6	ENSLCAP00010040539	ENSLCAP00010038040	Damage-specific DNA binding protein 1.	Deacetylase sirtuin-type domain-containing protein.	0.421
Ddb1	sirt7	ENSLCAP00010040539	ENSLCAP00010011384	Damage-specific DNA binding protein 1.	Deacetylase sirtuin-type domain-containing protein.	0.604
ENSLCAP00010014729	Sirt1	ENSLCAP00010014729	ENSLCAP00010015909	Forkhead box K1.	Deacetylase sirtuin-type domain-containing protein.	0.405
ENSLCAP00010014729	ogt	ENSLCAP00010014729	ENSLCAP00010031665	Forkhead box K1.	TPR_REGION domain-containing protein.	0.699
ENSLCAP00010023432	Ddb1	ENSLCAP00010023432	ENSLCAP00010040539	E1A binding protein p300 b.	Damage-specific DNA binding protein 1.	0.552
ENSLCAP00010023432	Sirt1	ENSLCAP00010023432	ENSLCAP00010015909	E1A binding protein p300 b.	Deacetylase sirtuin-type domain-containing protein.	0.762
IGFBP3	igf2	ENSLCAP00010021052	ENSLCAP00010038551	Uncharacterized protein.	Insulin-like growth factor II.	0.893
IGFBP4	igf2	ENSLCAP00010020612	ENSLCAP00010038551	Uncharacterized protein.	Insulin-like growth factor II.	0.689
LOC108874502	Sirt1	ENSLCAP00010013875	ENSLCAP00010015909	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.405
LOC108874502	ogt	ENSLCAP00010013875	ENSLCAP00010031665	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.699
LOC108875187	Lepr	ENSLCAP00010024792	ENSLCAP00010020309	Uncharacterized protein.	Leptin receptor.	0.845
LOC108875187	igf2	ENSLCAP00010024792	ENSLCAP00010038551	Uncharacterized protein.	Insulin-like growth factor II.	0.476
LOC108875187	pth	ENSLCAP00010024792	ENSLCAP00010038320	Uncharacterized protein.	Uncharacterized protein.	0.408
LOC108885279	Sirt1	ENSLCAP00010041835	ENSLCAP00010015909	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.405
LOC108885279	ogt	ENSLCAP00010041835	ENSLCAP00010031665	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.699
Lepr	LOC108875187	ENSLCAP00010020309	ENSLCAP00010024792	Leptin receptor.	Uncharacterized protein.	0.845
Sirt1	Ddb1	ENSLCAP00010015909	ENSLCAP00010040539	Deacetylase sirtuin-type domain-containing protein.	Damage-specific DNA binding protein 1.	0.446