(21 nodes) Secretory granule organization network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	agfg1	Arf-GAP domain-containing protein. (598 aa)
	dtnbp1	Uncharacterized protein. (228 aa)
	bloc1s3	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (196 aa)
	snx19	Uncharacterized protein. (981 aa)
	LOC108879473	Rab-GAP TBC domain-containing protein. (414 aa)
	LOC108883342	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (280 aa)
	LOC108883341	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
	ENSLCAP00010007608	Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (277 aa)
	serpine2	SERPIN domain-containing protein; Belongs to the serpin family. (397 aa)
	ENSLCAP00010003849	Uncharacterized protein. (120 aa)
	ENSLCAP00010002252	Sorting nexin 19a. (896 aa)
	ENSLCAP00010057181	Uncharacterized protein. (141 aa)
	LOC108883726	Arf-GAP domain-containing protein. (498 aa)
	tmf1	TMF_TATA_bd domain-containing protein. (1161 aa)
	ENSLCAP00010045339	Coiled-coil domain containing 136b. (328 aa)
	Hps4	Hermansky-Pudlak syndrome 4. (687 aa)
	ENSLCAP00010044953	Coiled-coil domain containing 136b. (300 aa)
	ENSLCAP00010044852	HMG box domain-containing protein. (243 aa)
	VPS13B	Uncharacterized protein. (4064 aa)
	ENSLCAP00010042834	Uncharacterized protein. (302 aa)
	Tbc1d20	TBC1 domain family, member 20. (388 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLCAP00010042834	bloc1s3	ENSLCAP00010042834	ENSLCAP00010018947	Uncharacterized protein.	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.	0.775
Hps4	bloc1s3	ENSLCAP00010044963	ENSLCAP00010018947	Hermansky-Pudlak syndrome 4.	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.	0.609
Hps4	dtnbp1	ENSLCAP00010044963	ENSLCAP00010030100	Hermansky-Pudlak syndrome 4.	Uncharacterized protein.	0.596
bloc1s3	ENSLCAP00010042834	ENSLCAP00010018947	ENSLCAP00010042834	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.	Uncharacterized protein.	0.775
bloc1s3	Hps4	ENSLCAP00010018947	ENSLCAP00010044963	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.	Hermansky-Pudlak syndrome 4.	0.609
bloc1s3	dtnbp1	ENSLCAP00010018947	ENSLCAP00010030100	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.	Uncharacterized protein.	0.944
dtnbp1	Hps4	ENSLCAP00010030100	ENSLCAP00010044963	Uncharacterized protein.	Hermansky-Pudlak syndrome 4.	0.596
dtnbp1	bloc1s3	ENSLCAP00010030100	ENSLCAP00010018947	Uncharacterized protein.	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.	0.944