(84 nodes) Glucose homeostasis network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prkaa1	Non-specific serine/threonine protein kinase. (573 aa)
	gck	Phosphotransferase. (555 aa)
	LOC108882618	Uncharacterized protein. (512 aa)
	LOC108899599	G_PROTEIN_RECEP_F1_2 domain-containing protein. (340 aa)
	rps6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
	LOC108898233	Uncharacterized protein. (637 aa)
	ENSLCAP00010009201	Si:ch211-225b10.4. (902 aa)
	yap1	Uncharacterized protein. (450 aa)
	MCUB	MCU domain-containing protein. (336 aa)
	aspscr1	Uncharacterized protein. (617 aa)
	Bhlha15	Basic helix-loop-helix family, member a15. (162 aa)
	adcy8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1240 aa)
	PCK1	Uncharacterized protein. (624 aa)
	ENSLCAP00010013205	Nerve growth factor receptor a (TNFR superfamily, member 16). (268 aa)
	LOC108897837	Uncharacterized protein. (227 aa)
	LOC108874502	Uncharacterized protein. (617 aa)
	Zbtb20	Zinc finger and BTB domain containing 20. (525 aa)
	ENSLCAP00010014590	CCDC144C domain-containing protein. (1218 aa)
	ENSLCAP00010014729	Forkhead box K1. (557 aa)
	Wisp1	WNT1 inducible signaling pathway protein 1a. (340 aa)
	Sirt1	Deacetylase sirtuin-type domain-containing protein. (705 aa)
	prkaa2	Non-specific serine/threonine protein kinase. (557 aa)
	LOC108878991	Pannexin_like domain-containing protein. (851 aa)
	fitm2	Uncharacterized protein. (255 aa)
	Lepr	Leptin receptor. (1149 aa)
	LOC108895615	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1184 aa)
	gas6	Uncharacterized protein. (651 aa)
	SPX	Spexin hormone. (120 aa)
	ENSLCAP00010024560	MCU domain-containing protein. (249 aa)
	LOC108875187	Uncharacterized protein. (161 aa)
	ENSLCAP00010025007	Kruppel-like factor 7b. (293 aa)
	ENSLCAP00010026081	HNF1 homeobox Ba. (586 aa)
	pdx1	Homeobox domain-containing protein. (261 aa)
	ENSLCAP00010027390	Uncharacterized protein. (1625 aa)
	mbd5	Uncharacterized protein. (1445 aa)
	hnf1b	Homeobox domain-containing protein. (573 aa)
	LOC108880495	Uncharacterized protein. (364 aa)
	gclc	Uncharacterized protein. (633 aa)
	LOC108893952	MFS domain-containing protein. (450 aa)
	ENSLCAP00010033367	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (191 aa)
	LOC108884156	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
	Xbp1	BZIP domain-containing protein. (264 aa)
	ENSLCAP00010033852	Si:dkey-211g8.9. (295 aa)
	gpi	Glucose-6-phosphate isomerase; Belongs to the GPI family. (578 aa)
	mcu	MCU domain-containing protein. (377 aa)
	nr1h4	Uncharacterized protein. (485 aa)
	Stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (436 aa)
	Znf236	Uncharacterized protein. (372 aa)
	ncoa5	RRM domain-containing protein. (636 aa)
	LOC108894950	Uncharacterized protein. (380 aa)
	csrp3	Uncharacterized protein. (193 aa)
	sirt6	Deacetylase sirtuin-type domain-containing protein. (351 aa)
	ENSLCAP00010038563	Uncharacterized protein. (919 aa)
	LOC108878545	Uncharacterized protein. (937 aa)
	wfs1	Uncharacterized protein. (964 aa)
	bad	Uncharacterized protein. (229 aa)
	HK1	Uncharacterized protein. (919 aa)
	Rfx6	Regulatory factor X, 6. (967 aa)
	LOC108885279	Uncharacterized protein. (616 aa)
	LOC108884388	Uncharacterized protein. (624 aa)
	ENSLCAP00010042296	Spexin hormone. (120 aa)
	LOC108873031	Uncharacterized protein. (266 aa)
	LOC108873040	Uncharacterized protein. (301 aa)
	NOX4	NADPH oxidase 4. (515 aa)
	ENSLCAP00010046784	Uncharacterized protein. (906 aa)
	stxbp3	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)
	ENSLCAP00010047467	Nuclear receptor subfamily 1, group d, member 1. (549 aa)
	LOC108897190	Uncharacterized protein. (275 aa)
	ENSLCAP00010048315	Nuclear receptor subfamily 1, group D, member 4b. (392 aa)
	lrrc8d	Pannexin_like domain-containing protein. (852 aa)
	ENSLCAP00010050425	Uncharacterized protein. (580 aa)
	ENSLCAP00010051369	Nuclear receptor subfamily 1, group D, member 4a. (575 aa)
	LOC108891355	Uncharacterized protein. (574 aa)
	park7	DJ-1_PfpI domain-containing protein. (189 aa)
	ENSLCAP00010054314	Si:ch211-132f19.7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (844 aa)
	adipor1	Uncharacterized protein. (376 aa)
	ENSLCAP00010056155	Uncharacterized protein. (1005 aa)
	slc37a4	MFS domain-containing protein. (429 aa)
	LOC108885229	Glucose-6-phosphate isomerase; Belongs to the GPI family. (560 aa)
	ENSLCAP00010057066	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	HECTD4	HECT domain-containing protein. (4445 aa)
	gpr1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	ENSLCAP00010060249	Wolfram syndrome 1a (wolframin). (703 aa)
	SLC8B1	Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (556 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLCAP00010014729	Sirt1	ENSLCAP00010014729	ENSLCAP00010015909	Forkhead box K1.	Deacetylase sirtuin-type domain-containing protein.	0.405
ENSLCAP00010014729	mbd5	ENSLCAP00010014729	ENSLCAP00010029089	Forkhead box K1.	Uncharacterized protein.	0.510
ENSLCAP00010038563	ENSLCAP00010050425	ENSLCAP00010038563	ENSLCAP00010050425	Uncharacterized protein.	Uncharacterized protein.	0.864
ENSLCAP00010038563	LOC108885229	ENSLCAP00010038563	ENSLCAP00010056607	Uncharacterized protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.642
ENSLCAP00010038563	gpi	ENSLCAP00010038563	ENSLCAP00010034122	Uncharacterized protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.642
ENSLCAP00010038563	pdx1	ENSLCAP00010038563	ENSLCAP00010027049	Uncharacterized protein.	Homeobox domain-containing protein.	0.404
ENSLCAP00010046784	ENSLCAP00010050425	ENSLCAP00010046784	ENSLCAP00010050425	Uncharacterized protein.	Uncharacterized protein.	0.822
ENSLCAP00010046784	ENSLCAP00010056155	ENSLCAP00010046784	ENSLCAP00010056155	Uncharacterized protein.	Uncharacterized protein.	0.902
ENSLCAP00010046784	HK1	ENSLCAP00010046784	ENSLCAP00010041157	Uncharacterized protein.	Uncharacterized protein.	0.902
ENSLCAP00010046784	LOC108878545	ENSLCAP00010046784	ENSLCAP00010038938	Uncharacterized protein.	Uncharacterized protein.	0.902
ENSLCAP00010046784	LOC108885229	ENSLCAP00010046784	ENSLCAP00010056607	Uncharacterized protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.962
ENSLCAP00010046784	gpi	ENSLCAP00010046784	ENSLCAP00010034122	Uncharacterized protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.962
ENSLCAP00010050425	ENSLCAP00010038563	ENSLCAP00010050425	ENSLCAP00010038563	Uncharacterized protein.	Uncharacterized protein.	0.864
ENSLCAP00010050425	ENSLCAP00010046784	ENSLCAP00010050425	ENSLCAP00010046784	Uncharacterized protein.	Uncharacterized protein.	0.822
ENSLCAP00010050425	ENSLCAP00010056155	ENSLCAP00010050425	ENSLCAP00010056155	Uncharacterized protein.	Uncharacterized protein.	0.864
ENSLCAP00010050425	HK1	ENSLCAP00010050425	ENSLCAP00010041157	Uncharacterized protein.	Uncharacterized protein.	0.864
ENSLCAP00010050425	LOC108878545	ENSLCAP00010050425	ENSLCAP00010038938	Uncharacterized protein.	Uncharacterized protein.	0.864
ENSLCAP00010050425	gck	ENSLCAP00010050425	ENSLCAP00010002256	Uncharacterized protein.	Phosphotransferase.	0.883
ENSLCAP00010056155	ENSLCAP00010046784	ENSLCAP00010056155	ENSLCAP00010046784	Uncharacterized protein.	Uncharacterized protein.	0.902
ENSLCAP00010056155	ENSLCAP00010050425	ENSLCAP00010056155	ENSLCAP00010050425	Uncharacterized protein.	Uncharacterized protein.	0.864