(59 nodes) Regulation of fat cell differentiation network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	klf5	Uncharacterized protein. (509 aa)
	noct	Endo/exonuclease/phosphatase domain-containing protein. (460 aa)
	LOC108900755	ZnMc domain-containing protein. (494 aa)
	ENSLCAP00010029194	Coactivator-associated arginine methyltransferase 1, like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (544 aa)
	tmem64	Uncharacterized protein. (352 aa)
	syap1	BSD domain-containing protein. (354 aa)
	FFAR4	G_PROTEIN_RECEP_F1_2 domain-containing protein. (352 aa)
	zfpm2	Uncharacterized protein. (1179 aa)
	ENSLCAP00010032096	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (582 aa)
	Xbp1	BZIP domain-containing protein. (264 aa)
	ZADH2	PKS_ER domain-containing protein. (404 aa)
	LOC108890483	CCAAT/enhancer-binding protein. (301 aa)
	ddit3	Uncharacterized protein. (312 aa)
	napepld	Lactamase_B domain-containing protein. (446 aa)
	ENSLCAP00010037929	Protein kinase domain-containing protein. (358 aa)
	sirt6	Deacetylase sirtuin-type domain-containing protein. (351 aa)
	GATA2	GATA binding protein 2. (458 aa)
	dusp10	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (472 aa)
	Sfrp2	Secreted frizzled-related protein 2. (284 aa)
	crebl2	BZIP domain-containing protein. (122 aa)
	LOC108893693	Uncharacterized protein. (888 aa)
	LOC108886611	Uncharacterized protein. (389 aa)
	ENSLCAP00010047467	Nuclear receptor subfamily 1, group d, member 1. (549 aa)
	ENSLCAP00010047716	Kruppel-like factor 5 like. (230 aa)
	LOC108885640	Uncharacterized protein. (458 aa)
	aamdc	Uncharacterized protein. (140 aa)
	ENSLCAP00010051369	Nuclear receptor subfamily 1, group D, member 4a. (575 aa)
	Medag	Uncharacterized protein. (177 aa)
	sav1	Uncharacterized protein. (424 aa)
	ENSLCAP00010053976	Uncharacterized protein. (294 aa)
	zfp36l2	Uncharacterized protein. (429 aa)
	LOC108897739	BSD domain-containing protein. (364 aa)
	metrnl	Uncharacterized protein. (286 aa)
	cmklr1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (344 aa)
	ENSLCAP00010025630	Sortilin. (753 aa)
	LOC108901777	Uncharacterized protein. (358 aa)
	LOC108898754	C3H1-type domain-containing protein. (626 aa)
	LOC108900154	Endo/exonuclease/phosphatase domain-containing protein. (394 aa)
	ENSLCAP00010022960	Uncharacterized protein. (101 aa)
	flcn	UDENN FLCN/SMCR8-type domain-containing protein. (563 aa)
	LOC108889007	Uncharacterized protein. (428 aa)
	LOC108888398	Uncharacterized protein. (430 aa)
	Ptgs2	Prostaglandin-endoperoxide synthase 2b. (612 aa)
	Sirt1	Deacetylase sirtuin-type domain-containing protein. (705 aa)
	ENSLCAP00010015686	Protein kinase domain-containing protein. (308 aa)
	LOC108876160	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	Wisp1	WNT1 inducible signaling pathway protein 1a. (340 aa)
	ENSLCAP00010015123	Formyl peptide receptor 1; Belongs to the G-protein coupled receptor 1 family. (401 aa)
	ENSLCAP00010014835	Matrix metallopeptidase 11a. (449 aa)
	ENSLCAP00010014590	CCDC144C domain-containing protein. (1218 aa)
	e2f1	E2F_TDP domain-containing protein. (454 aa)
	ENSLCAP00010013357	Delta-like 2 homolog (Drosophila). (343 aa)
	LOC108883996	C3H1-type domain-containing protein. (664 aa)
	ENSLCAP00010004541	Zinc finger protein 36, C3H type-like 1a. (422 aa)
	LOC108880494	Uncharacterized protein. (513 aa)
	LOC108879766	G_PROTEIN_RECEP_F1_2 domain-containing protein. (502 aa)
	Asxl2	ASXL transcriptional regulator 2. (923 aa)
	vstm2a	Ig-like domain-containing protein. (236 aa)
	Rreb1	Ras responsive element binding protein 1a. (1275 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLCAP00010015686	LOC108890483	ENSLCAP00010015686	ENSLCAP00010035287	Protein kinase domain-containing protein.	CCAAT/enhancer-binding protein.	0.473
ENSLCAP00010015686	ddit3	ENSLCAP00010015686	ENSLCAP00010036184	Protein kinase domain-containing protein.	Uncharacterized protein.	0.519
ENSLCAP00010022960	LOC108890483	ENSLCAP00010022960	ENSLCAP00010035287	Uncharacterized protein.	CCAAT/enhancer-binding protein.	0.565
ENSLCAP00010029194	GATA2	ENSLCAP00010029194	ENSLCAP00010038933	Coactivator-associated arginine methyltransferase 1, like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	GATA binding protein 2.	0.448
ENSLCAP00010029194	LOC108885640	ENSLCAP00010029194	ENSLCAP00010048227	Coactivator-associated arginine methyltransferase 1, like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.448
ENSLCAP00010032096	GATA2	ENSLCAP00010032096	ENSLCAP00010038933	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	GATA binding protein 2.	0.448
ENSLCAP00010032096	LOC108885640	ENSLCAP00010032096	ENSLCAP00010048227	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.448
ENSLCAP00010037929	LOC108890483	ENSLCAP00010037929	ENSLCAP00010035287	Protein kinase domain-containing protein.	CCAAT/enhancer-binding protein.	0.473
ENSLCAP00010037929	ddit3	ENSLCAP00010037929	ENSLCAP00010036184	Protein kinase domain-containing protein.	Uncharacterized protein.	0.519
ENSLCAP00010047716	LOC108890483	ENSLCAP00010047716	ENSLCAP00010035287	Kruppel-like factor 5 like.	CCAAT/enhancer-binding protein.	0.565
GATA2	ENSLCAP00010029194	ENSLCAP00010038933	ENSLCAP00010029194	GATA binding protein 2.	Coactivator-associated arginine methyltransferase 1, like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.448
GATA2	ENSLCAP00010032096	ENSLCAP00010038933	ENSLCAP00010032096	GATA binding protein 2.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.448
GATA2	zfpm2	ENSLCAP00010038933	ENSLCAP00010031988	GATA binding protein 2.	Uncharacterized protein.	0.566
LOC108876160	Ptgs2	ENSLCAP00010015620	ENSLCAP00010017777	Transforming growth factor beta; Belongs to the TGF-beta family.	Prostaglandin-endoperoxide synthase 2b.	0.407
LOC108880494	LOC108890483	ENSLCAP00010004324	ENSLCAP00010035287	Uncharacterized protein.	CCAAT/enhancer-binding protein.	0.565
LOC108885640	ENSLCAP00010029194	ENSLCAP00010048227	ENSLCAP00010029194	Uncharacterized protein.	Coactivator-associated arginine methyltransferase 1, like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.448
LOC108885640	ENSLCAP00010032096	ENSLCAP00010048227	ENSLCAP00010032096	Uncharacterized protein.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.448
LOC108885640	zfpm2	ENSLCAP00010048227	ENSLCAP00010031988	Uncharacterized protein.	Uncharacterized protein.	0.558
LOC108890483	ENSLCAP00010015686	ENSLCAP00010035287	ENSLCAP00010015686	CCAAT/enhancer-binding protein.	Protein kinase domain-containing protein.	0.473
LOC108890483	ENSLCAP00010022960	ENSLCAP00010035287	ENSLCAP00010022960	CCAAT/enhancer-binding protein.	Uncharacterized protein.	0.565