(37 nodes) Neuron apoptotic process network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLCAP00010044762	Uncharacterized protein. (873 aa)
	ENSLCAP00010000256	FIIND domain-containing protein. (1226 aa)
	ENSLCAP00010001250	Nuclear factor of activated T cells 4. (464 aa)
	NCSTN	Nicastrin. (696 aa)
	LOC108880245	Uncharacterized protein. (268 aa)
	Nf1	Neurofibromin 1b. (2806 aa)
	Pigt	Phosphatidylinositol glycan anchor biosynthesis, class T. (660 aa)
	cdk5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (292 aa)
	LOC108884936	J domain-containing protein. (197 aa)
	ENSLCAP00010013205	Nerve growth factor receptor a (TNFR superfamily, member 16). (268 aa)
	bax	Uncharacterized protein. (192 aa)
	ENSLCAP00010014879	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2044 aa)
	sncb	Beta-synuclein; Belongs to the synuclein family. (135 aa)
	LOC108880505	Uncharacterized protein. (195 aa)
	tmtc4	TPR_REGION domain-containing protein. (741 aa)
	ENSLCAP00010023595	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a. (223 aa)
	siah1	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (341 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
	LOC108881726	Uncharacterized protein. (147 aa)
	LOC108876072	Uncharacterized protein. (269 aa)
	diablo	Uncharacterized protein. (237 aa)
	rapsn	Uncharacterized protein. (423 aa)
	ENSLCAP00010031592	Uncharacterized protein. (1221 aa)
	lig4	DNA ligase. (918 aa)
	cln8	TLC domain-containing protein. (285 aa)
	ppargc1a	RRM domain-containing protein. (951 aa)
	LOC108890509	J domain-containing protein. (221 aa)
	tnfrsf21	Uncharacterized protein. (694 aa)
	ENSLCAP00010044755	Si:ch73-252p3.1. (1199 aa)
	aifm1	Uncharacterized protein. (745 aa)
	LOC108886742	J domain-containing protein. (214 aa)
	LOC108886974	Glyceraldehyde-3-phosphate dehydrogenase. (347 aa)
	rb1	Uncharacterized protein. (913 aa)
	LOC108887427	J domain-containing protein. (201 aa)
	adnp	Uncharacterized protein. (1070 aa)
	ENSLCAP00010059447	Uncharacterized protein. (1783 aa)
	casp9	Uncharacterized protein; Belongs to the peptidase C14A family. (457 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLCAP00010000256	casp9	ENSLCAP00010000256	ENSLCAP00010059818	FIIND domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.409
ENSLCAP00010013205	NCSTN	ENSLCAP00010013205	ENSLCAP00010001927	Nerve growth factor receptor a (TNFR superfamily, member 16).	Nicastrin.	0.462
ENSLCAP00010044755	casp9	ENSLCAP00010044755	ENSLCAP00010059818	Si:ch73-252p3.1.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.409
ENSLCAP00010044762	casp9	ENSLCAP00010044762	ENSLCAP00010059818	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.409
LOC108876072	LOC108880245	ENSLCAP00010027612	ENSLCAP00010002139	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC108876072	aifm1	ENSLCAP00010027612	ENSLCAP00010048385	Uncharacterized protein.	Uncharacterized protein.	0.414
LOC108876072	casp9	ENSLCAP00010027612	ENSLCAP00010059818	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.666
LOC108876072	diablo	ENSLCAP00010027612	ENSLCAP00010027680	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC108880245	LOC108876072	ENSLCAP00010002139	ENSLCAP00010027612	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC108880245	aifm1	ENSLCAP00010002139	ENSLCAP00010048385	Uncharacterized protein.	Uncharacterized protein.	0.414
LOC108880245	casp9	ENSLCAP00010002139	ENSLCAP00010059818	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.666
LOC108880245	diablo	ENSLCAP00010002139	ENSLCAP00010027680	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC108880505	casp9	ENSLCAP00010018598	ENSLCAP00010059818	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.705
LOC108886974	gapdh	ENSLCAP00010053573	ENSLCAP00010023964	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.901
LOC108886974	siah1	ENSLCAP00010053573	ENSLCAP00010023883	Glyceraldehyde-3-phosphate dehydrogenase.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.488
NCSTN	ENSLCAP00010013205	ENSLCAP00010001927	ENSLCAP00010013205	Nicastrin.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.462
NCSTN	aifm1	ENSLCAP00010001927	ENSLCAP00010048385	Nicastrin.	Uncharacterized protein.	0.437
NCSTN	cdk5	ENSLCAP00010001927	ENSLCAP00010010142	Nicastrin.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.434
aifm1	LOC108876072	ENSLCAP00010048385	ENSLCAP00010027612	Uncharacterized protein.	Uncharacterized protein.	0.414
aifm1	LOC108880245	ENSLCAP00010048385	ENSLCAP00010002139	Uncharacterized protein.	Uncharacterized protein.	0.414