82 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108877739	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
	poldip2	ApaG domain-containing protein. (388 aa)
	KIF23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (982 aa)
	ENSLCAP00010000930	EGF-like domain-containing protein. (139 aa)
	LOC108872675	Uncharacterized protein. (145 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	ENSLCAP00010002675	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (556 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
	PDGFA	Platelet derived growth factor subunit A. (161 aa)
	ENSLCAP00010004274	Uncharacterized protein. (639 aa)
	ptn	Uncharacterized protein. (223 aa)
	ENSLCAP00010005763	HP domain-containing protein. (1936 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
	LOC108886096	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (201 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (226 aa)
	ENSLCAP00010008196	Supervillin a. (2116 aa)
	LOC108874127	EGF-like domain-containing protein. (186 aa)
	HDGF	Heparin binding growth factor. (223 aa)
	map10	Uncharacterized protein. (840 aa)
	LOC108880752	Uncharacterized protein. (201 aa)
	Cxcr5	Chemokine (C-X-C motif) receptor 5; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	LOC108882441	Uncharacterized protein. (556 aa)
	Prok1	Prokineticin 1. (144 aa)
	ENSLCAP00010014879	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2044 aa)
	LOC108876160	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	ENSLCAP00010019198	Uncharacterized protein. (388 aa)
	ENSLCAP00010020399	Transforming growth factor, alpha. (292 aa)
	ENSLCAP00010020503	GIPC PDZ domain containing family, member 3. (342 aa)
	ENSLCAP00010020668	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1183 aa)
	ENSLCAP00010021412	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (174 aa)
	ENSLCAP00010021801	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	htr2b	G_PROTEIN_RECEP_F1_2 domain-containing protein. (473 aa)
	ENSLCAP00010025014	Growth differentiation factor 3. (345 aa)
	drd3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (457 aa)
	CDC42	Uncharacterized protein. (227 aa)
	LOC108896919	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (169 aa)
	garem2	CABIT domain-containing protein. (724 aa)
	Cspp1	Centrosome and spindle pole associated protein 1a. (1032 aa)
	LOC108886589	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1028 aa)
	ENSLCAP00010030874	Uncharacterized protein. (69 aa)
	vegfc	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (422 aa)
	LOC108882928	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
	LOC108891536	Uncharacterized protein. (639 aa)
	ENSLCAP00010033140	Supervillin d. (1321 aa)
	CUL3	CULLIN_2 domain-containing protein; Belongs to the cullin family. (766 aa)
	ENSLCAP00010034308	Uncharacterized protein. (427 aa)
	LOC108887138	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (227 aa)
	ENSLCAP00010038402	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (147 aa)
	igf2	Insulin-like growth factor II. (215 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
	cenpv	GFA domain-containing protein. (178 aa)
	tgfb3	Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
	fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
	Vegfb	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (147 aa)
	ENSLCAP00010042867	Uncharacterized protein. (147 aa)
	LOC108872574	Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
	LOC108880235	Uncharacterized protein. (175 aa)
	LOC108892573	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (207 aa)
	LOC108886600	CULLIN_2 domain-containing protein; Belongs to the cullin family. (771 aa)
	pdgfd	Uncharacterized protein. (377 aa)
	pdgfc	Uncharacterized protein; Belongs to the PDGF/VEGF growth factor family. (342 aa)
	ENSLCAP00010048462	Aurora kinase B; Belongs to the protein kinase superfamily. (335 aa)
	itgb1bp1	PID domain-containing protein. (198 aa)
	Racgap1	Rac GTPase activating protein 1. (662 aa)
	LOC108877499	Uncharacterized protein. (191 aa)
	LOC108878374	Interleukin-1. (278 aa)
	LOC108887526	Uncharacterized protein. (191 aa)
	gipc2	PDZ domain-containing protein. (329 aa)
	ENSLCAP00010054962	Uncharacterized protein. (301 aa)
	cdc14a	Uncharacterized protein. (619 aa)
	prok2	Prokineticin domain-containing protein. (135 aa)
	ect2	Uncharacterized protein. (1130 aa)
	LOC108902679	PDZ domain-containing protein. (337 aa)
	Garem1	GRB2 associated, regulator of MAPK1. (860 aa)
	Igf1	Insulin-like growth factor 1. (186 aa)
	fgf17	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	LOC108882499	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (573 aa)
	ENSLCAP00010059447	Uncharacterized protein. (1783 aa)
	nkx3-1	Homeobox domain-containing protein. (195 aa)
	LOC108887165	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (587 aa)
	ENSLCAP00010060148	Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (229 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSLCAP00010000930	ENSLCAP00010026260	ENSLCAP00010000930	Uncharacterized protein.	EGF-like domain-containing protein.	0.540
CDC42	ENSLCAP00010004274	ENSLCAP00010026260	ENSLCAP00010004274	Uncharacterized protein.	Uncharacterized protein.	0.758
CDC42	ENSLCAP00010020399	ENSLCAP00010026260	ENSLCAP00010020399	Uncharacterized protein.	Transforming growth factor, alpha.	0.559
CDC42	ENSLCAP00010038402	ENSLCAP00010026260	ENSLCAP00010038402	Uncharacterized protein.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.415
CDC42	LOC108886096	ENSLCAP00010026260	ENSLCAP00010007210	Uncharacterized protein.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.415
CDC42	LOC108891536	ENSLCAP00010026260	ENSLCAP00010032969	Uncharacterized protein.	Uncharacterized protein.	0.758
CDC42	Racgap1	ENSLCAP00010026260	ENSLCAP00010049616	Uncharacterized protein.	Rac GTPase activating protein 1.	0.758
CDC42	ect2	ENSLCAP00010026260	ENSLCAP00010055883	Uncharacterized protein.	Uncharacterized protein.	0.717
CUL3	ENSLCAP00010048462	ENSLCAP00010033441	ENSLCAP00010048462	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.660
CUL3	LOC108886600	ENSLCAP00010033441	ENSLCAP00010045383	CULLIN_2 domain-containing protein; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.900
Cxcr5	LOC108878374	ENSLCAP00010011359	ENSLCAP00010051161	Chemokine (C-X-C motif) receptor 5; Belongs to the G-protein coupled receptor 1 family.	Interleukin-1.	0.429
ENSLCAP00010000930	CDC42	ENSLCAP00010000930	ENSLCAP00010026260	EGF-like domain-containing protein.	Uncharacterized protein.	0.540
ENSLCAP00010000930	ENSLCAP00010020399	ENSLCAP00010000930	ENSLCAP00010020399	EGF-like domain-containing protein.	Transforming growth factor, alpha.	0.766
ENSLCAP00010000930	LOC108874127	ENSLCAP00010000930	ENSLCAP00010008226	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.806
ENSLCAP00010000930	LOC108877499	ENSLCAP00010000930	ENSLCAP00010050203	EGF-like domain-containing protein.	Uncharacterized protein.	0.540
ENSLCAP00010000930	LOC108880752	ENSLCAP00010000930	ENSLCAP00010011091	EGF-like domain-containing protein.	Uncharacterized protein.	0.453
ENSLCAP00010000930	LOC108887526	ENSLCAP00010000930	ENSLCAP00010051906	EGF-like domain-containing protein.	Uncharacterized protein.	0.453
ENSLCAP00010002675	ENSLCAP00010034308	ENSLCAP00010002675	ENSLCAP00010034308	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	Uncharacterized protein.	0.585
ENSLCAP00010002675	ENSLCAP00010048462	ENSLCAP00010002675	ENSLCAP00010048462	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.564
ENSLCAP00010002675	LOC108882441	ENSLCAP00010002675	ENSLCAP00010011841	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	Uncharacterized protein.	0.585