(37 nodes) Execution phase of apoptosis network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLCAP00010035743	XK-related protein. (626 aa)
	aifm3	Rieske domain-containing protein. (599 aa)
	Dffb	DNA fragmentation factor, beta polypeptide (caspase-activated DNase). (359 aa)
	casp9	Uncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
	ENSLCAP00010059112	Caspase 8, apoptosis-related cysteine peptidase, like 2; Belongs to the peptidase C14A family. (647 aa)
	ENSLCAP00010056814	XK-related protein. (539 aa)
	LOC108891868	XK-related protein. (568 aa)
	cflar	Uncharacterized protein; Belongs to the peptidase C14A family. (516 aa)
	endog	Endonuclease. (299 aa)
	ENSLCAP00010045749	Apoptosis-inducing factor, mitochondrion-associated, 5. (472 aa)
	madd	UDENN domain-containing protein. (1655 aa)
	ENSLCAP00010039651	XK-related protein. (589 aa)
	ENSLCAP00010037970	annotation not available (406 aa)
	Xkr8	XK-related protein. (417 aa)
	ENSLCAP00010035796	XK-related protein. (407 aa)
	ENSLCAP00010032511	Uncharacterized protein. (335 aa)
	ENSLCAP00010032497	Uncharacterized protein. (319 aa)
	ENSLCAP00010032485	Deoxyribonuclease II beta. (436 aa)
	xkr6	XK-related protein. (602 aa)
	Cdk5rap3	CDK5 regulatory subunit associated protein 3. (521 aa)
	xkr4	XK-related protein. (605 aa)
	ENSLCAP00010026224	Apoptosis-inducing factor, mitochondrion-associated, 4. (364 aa)
	blcap	Uncharacterized protein. (87 aa)
	casp2	Uncharacterized protein; Belongs to the peptidase C14A family. (468 aa)
	Sharpin	SHANK-associated RH domain interacting protein. (435 aa)
	ENSLCAP00010017685	CARD domain-containing protein. (123 aa)
	LOC108883933	SAP domain-containing protein. (1724 aa)
	casp6	Uncharacterized protein; Belongs to the peptidase C14A family. (301 aa)
	dffa	CIDE-N domain-containing protein. (321 aa)
	Dicer1	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1896 aa)
	ENSLCAP00010008403	Uncharacterized protein; Belongs to the peptidase C14A family. (480 aa)
	Catip	Uncharacterized protein; Belongs to the peptidase C14A family. (459 aa)
	ENSLCAP00010004451	Bromo domain-containing protein. (1021 aa)
	LOC108899584	Uncharacterized protein. (205 aa)
	dnase2	Uncharacterized protein. (378 aa)
	LOC108903047	SAP domain-containing protein. (1324 aa)
	dedd2	DED domain-containing protein. (412 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Catip	Dffb	ENSLCAP00010008252	ENSLCAP00010059848	Uncharacterized protein; Belongs to the peptidase C14A family.	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	0.430
Catip	LOC108899584	ENSLCAP00010008252	ENSLCAP00010003821	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.634
Catip	casp2	ENSLCAP00010008252	ENSLCAP00010021664	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.482
Catip	casp6	ENSLCAP00010008252	ENSLCAP00010010915	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.482
Catip	casp9	ENSLCAP00010008252	ENSLCAP00010059818	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.555
Catip	cflar	ENSLCAP00010008252	ENSLCAP00010048611	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.911
Dffb	Catip	ENSLCAP00010059848	ENSLCAP00010008252	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	Uncharacterized protein; Belongs to the peptidase C14A family.	0.430
Dffb	ENSLCAP00010008403	ENSLCAP00010059848	ENSLCAP00010008403	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	Uncharacterized protein; Belongs to the peptidase C14A family.	0.445
Dffb	ENSLCAP00010017685	ENSLCAP00010059848	ENSLCAP00010017685	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	CARD domain-containing protein.	0.413
Dffb	ENSLCAP00010059112	ENSLCAP00010059848	ENSLCAP00010059112	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	Caspase 8, apoptosis-related cysteine peptidase, like 2; Belongs to the peptidase C14A family.	0.445
Dffb	LOC108883933	ENSLCAP00010059848	ENSLCAP00010014342	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	SAP domain-containing protein.	0.426
Dffb	LOC108903047	ENSLCAP00010059848	ENSLCAP00010000329	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	SAP domain-containing protein.	0.426
Dffb	casp2	ENSLCAP00010059848	ENSLCAP00010021664	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	Uncharacterized protein; Belongs to the peptidase C14A family.	0.561
Dffb	casp6	ENSLCAP00010059848	ENSLCAP00010010915	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	Uncharacterized protein; Belongs to the peptidase C14A family.	0.670
Dffb	casp9	ENSLCAP00010059848	ENSLCAP00010059818	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	Uncharacterized protein; Belongs to the peptidase C14A family.	0.615
Dffb	cflar	ENSLCAP00010059848	ENSLCAP00010048611	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	Uncharacterized protein; Belongs to the peptidase C14A family.	0.629
Dffb	dffa	ENSLCAP00010059848	ENSLCAP00010009253	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	CIDE-N domain-containing protein.	0.987
ENSLCAP00010008403	Dffb	ENSLCAP00010008403	ENSLCAP00010059848	Uncharacterized protein; Belongs to the peptidase C14A family.	DNA fragmentation factor, beta polypeptide (caspase-activated DNase).	0.445
ENSLCAP00010008403	LOC108899584	ENSLCAP00010008403	ENSLCAP00010003821	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.665
ENSLCAP00010008403	casp2	ENSLCAP00010008403	ENSLCAP00010021664	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.567