(43 nodes) Negative regulation of extrinsic apoptotic signaling pathway network (Lates calcarifer)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	ENSLCAP00010007633	Si:dkeyp-80c12.4. (542 aa)
	zmynd11	Uncharacterized protein. (678 aa)
	brca1	Uncharacterized protein. (1411 aa)
	LOC108874380	Uncharacterized protein. (256 aa)
	SCG2	Uncharacterized protein. (641 aa)
	LOC108873210	Uncharacterized protein. (181 aa)
	Unc5b	Unc-5 netrin receptor B. (943 aa)
	map2k5	Uncharacterized protein; Belongs to the protein kinase superfamily. (449 aa)
	LOC108887076	Uncharacterized protein. (180 aa)
	ENSLCAP00010060028	Proteasome activator subunit 3. (272 aa)
	gfral	Uncharacterized protein. (437 aa)
	gata1	Uncharacterized protein. (365 aa)
	LOC108895090	Tyrosine-protein kinase. (543 aa)
	rnf34	RING-type domain-containing protein. (378 aa)
	ENSLCAP00010053086	SERPIN domain-containing protein; Belongs to the serpin family. (383 aa)
	LOC108878374	Interleukin-1. (278 aa)
	ENSLCAP00010050511	Galectin. (401 aa)
	LOC108893617	Uncharacterized protein. (765 aa)
	cflar	Uncharacterized protein; Belongs to the peptidase C14A family. (516 aa)
	zc3hc1	Uncharacterized protein. (510 aa)
	LOC108886611	Uncharacterized protein. (389 aa)
	Htt	Huntingtin. (3100 aa)
	LOC108874151	DED domain-containing protein. (130 aa)
	rffl	RING-type domain-containing protein. (348 aa)
	Sfrp2	Secreted frizzled-related protein 2. (284 aa)
	ENSLCAP00010041366	GATA binding protein 1a. (416 aa)
	ENSLCAP00010041083	DED domain-containing protein. (103 aa)
	LOC108898553	Uncharacterized protein. (256 aa)
	ENSLCAP00010037180	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (698 aa)
	serpine1	SERPIN domain-containing protein; Belongs to the serpin family. (391 aa)
	LOC108883528	Uncharacterized protein. (609 aa)
	ENSLCAP00010032567	Tyrosine-protein kinase. (526 aa)
	gclc	Uncharacterized protein. (633 aa)
	LOC108881792	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (492 aa)
	ENSLCAP00010026940	Tumor necrosis factor, alpha-induced protein 3. (777 aa)
	ENSLCAP00010026871	Galectin. (277 aa)
	PSME3	Proteasome activator subunit 3. (272 aa)
	Itprip	Inositol 1,4,5-trisphosphate receptor interacting protein. (382 aa)
	fgb	Fibrinogen C-terminal domain-containing protein. (492 aa)
	ENSLCAP00010012956	Ring finger protein 34b. (330 aa)
	ENSLCAP00010011169	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (357 aa)
	rb1cc1	ATG11 domain-containing protein. (1651 aa)
	LOC108882770	Uncharacterized protein. (691 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLCAP00010026940	LOC108878374	ENSLCAP00010026940	ENSLCAP00010051161	Tumor necrosis factor, alpha-induced protein 3.	Interleukin-1.	0.534
ENSLCAP00010032567	LOC108895090	ENSLCAP00010032567	ENSLCAP00010055478	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
ENSLCAP00010032567	map2k5	ENSLCAP00010032567	ENSLCAP00010001877	Tyrosine-protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.424
ENSLCAP00010053086	fgb	ENSLCAP00010053086	ENSLCAP00010014269	SERPIN domain-containing protein; Belongs to the serpin family.	Fibrinogen C-terminal domain-containing protein.	0.447
Htt	LOC108882770	ENSLCAP00010045630	ENSLCAP00010008657	Huntingtin.	Uncharacterized protein.	0.485
Htt	LOC108893617	ENSLCAP00010045630	ENSLCAP00010050141	Huntingtin.	Uncharacterized protein.	0.485
LOC108874380	LOC108898553	ENSLCAP00010005896	ENSLCAP00010037704	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC108874380	PSME3	ENSLCAP00010005896	ENSLCAP00010024749	Uncharacterized protein.	Proteasome activator subunit 3.	0.901
LOC108878374	ENSLCAP00010026940	ENSLCAP00010051161	ENSLCAP00010026940	Interleukin-1.	Tumor necrosis factor, alpha-induced protein 3.	0.534
LOC108878374	cflar	ENSLCAP00010051161	ENSLCAP00010048611	Interleukin-1.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.418
LOC108882770	Htt	ENSLCAP00010008657	ENSLCAP00010045630	Uncharacterized protein.	Huntingtin.	0.485
LOC108882770	LOC108893617	ENSLCAP00010008657	ENSLCAP00010050141	Uncharacterized protein.	Uncharacterized protein.	0.902
LOC108882770	brca1	ENSLCAP00010008657	ENSLCAP00010006276	Uncharacterized protein.	Uncharacterized protein.	0.594
LOC108893617	Htt	ENSLCAP00010050141	ENSLCAP00010045630	Uncharacterized protein.	Huntingtin.	0.485
LOC108893617	LOC108882770	ENSLCAP00010050141	ENSLCAP00010008657	Uncharacterized protein.	Uncharacterized protein.	0.902
LOC108893617	brca1	ENSLCAP00010050141	ENSLCAP00010006276	Uncharacterized protein.	Uncharacterized protein.	0.510
LOC108895090	ENSLCAP00010032567	ENSLCAP00010055478	ENSLCAP00010032567	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC108895090	map2k5	ENSLCAP00010055478	ENSLCAP00010001877	Tyrosine-protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.424
LOC108898553	LOC108874380	ENSLCAP00010037704	ENSLCAP00010005896	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC108898553	PSME3	ENSLCAP00010037704	ENSLCAP00010024749	Uncharacterized protein.	Proteasome activator subunit 3.	0.901