(25 nodes) Positive regulation of intrinsic apoptotic signaling pathway network (Lates calcarifer)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	ENSLCAP00010056777	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
	ENSLCAP00010000037	Uncharacterized protein. (267 aa)
	msx1	Homeobox domain-containing protein. (284 aa)
	ENSLCAP00010008651	SH2 domain-containing protein. (131 aa)
	LOC108890753	Protein kinase domain-containing protein. (531 aa)
	ENSLCAP00010013279	Protein inhibitor of activated STAT, 4a. (491 aa)
	bax	Uncharacterized protein. (192 aa)
	nck2	Cytoplasmic protein. (397 aa)
	Sirt1	Deacetylase sirtuin-type domain-containing protein. (705 aa)
	flcn	UDENN FLCN/SMCR8-type domain-containing protein. (563 aa)
	NCK1	Uncharacterized protein. (400 aa)
	ENSLCAP00010024823	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
	gsdme	Uncharacterized protein. (476 aa)
	ENSLCAP00010028058	Muscle segment homeobox 3. (166 aa)
	skil	c-SKI_SMAD_bind domain-containing protein. (772 aa)
	LOC108877149	Uncharacterized protein. (436 aa)
	ddit3	Uncharacterized protein. (312 aa)
	nkx3-1	Homeobox domain-containing protein. (195 aa)
	bad	Uncharacterized protein. (229 aa)
	ENSLCAP00010039727	Uncharacterized protein. (264 aa)
	LOC108890262	Cytoplasmic protein. (397 aa)
	ENSLCAP00010047538	F-box domain-containing protein. (743 aa)
	fbh1	F-box domain-containing protein. (1078 aa)
	ENSLCAP00010049644	NCK adaptor protein 2a. (267 aa)
	styxl1	Uncharacterized protein. (297 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLCAP00010024823	LOC108890753	ENSLCAP00010024823	ENSLCAP00010009740	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.904
LOC108890262	NCK1	ENSLCAP00010044874	ENSLCAP00010021502	Cytoplasmic protein.	Uncharacterized protein.	0.902
LOC108890262	nck2	ENSLCAP00010044874	ENSLCAP00010015422	Cytoplasmic protein.	Cytoplasmic protein.	0.900
LOC108890753	ENSLCAP00010024823	ENSLCAP00010009740	ENSLCAP00010024823	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.904
NCK1	LOC108890262	ENSLCAP00010021502	ENSLCAP00010044874	Uncharacterized protein.	Cytoplasmic protein.	0.902
NCK1	nck2	ENSLCAP00010021502	ENSLCAP00010015422	Uncharacterized protein.	Cytoplasmic protein.	0.902
bad	bax	ENSLCAP00010039579	ENSLCAP00010014364	Uncharacterized protein.	Uncharacterized protein.	0.745
bax	bad	ENSLCAP00010014364	ENSLCAP00010039579	Uncharacterized protein.	Uncharacterized protein.	0.745
nck2	LOC108890262	ENSLCAP00010015422	ENSLCAP00010044874	Cytoplasmic protein.	Cytoplasmic protein.	0.900
nck2	NCK1	ENSLCAP00010015422	ENSLCAP00010021502	Cytoplasmic protein.	Uncharacterized protein.	0.902