(47 nodes) Presynaptic active zone network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLCAP00010008847	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
	ENSLCAP00010008693	Uncharacterized protein. (1603 aa)
	ENSLCAP00010007118	Uncharacterized protein. (3203 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (908 aa)
	ENSLCAP00010059809	Uncharacterized protein. (3619 aa)
	cplx3	Uncharacterized protein. (156 aa)
	ENSLCAP00010057066	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	ENSLCAP00010054314	Si:ch211-132f19.7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (844 aa)
	LOC108878442	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (293 aa)
	STX19	t-SNARE coiled-coil homology domain-containing protein. (302 aa)
	ENSLCAP00010047272	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (282 aa)
	ENSLCAP00010047160	Syntaxin 1B; Belongs to the syntaxin family. (315 aa)
	ENSLCAP00010043777	Regulating synaptic membrane exocytosis 1a. (1300 aa)
	ERC2	ELKS/RAB6-interacting/CAST family member 2. (1167 aa)
	UNC13C	Unc-13 homolog C. (2568 aa)
	ENSLCAP00010042238	Syntaxin 11a. (276 aa)
	ENSLCAP00010042231	t-SNARE coiled-coil homology domain-containing protein. (307 aa)
	rims4	C2 domain-containing protein. (271 aa)
	nptn	Uncharacterized protein. (395 aa)
	ENSLCAP00010037720	Uncharacterized protein. (1486 aa)
	ERC1	ELKS/RAB6-interacting/CAST family member 1. (1151 aa)
	UNC13A	Unc-13 homolog A. (1623 aa)
	Zzef1	Zinc finger, ZZ-type with EF hand domain 1. (2948 aa)
	ENSLCAP00010036503	Uncharacterized protein. (563 aa)
	ENSLCAP00010036032	Cadherin_C domain-containing protein; Cadherins are calcium-dependent cell adhesion proteins. (176 aa)
	rims3	C2 domain-containing protein. (324 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1583 aa)
	stx4	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (364 aa)
	erc1	FIP-RBD domain-containing protein. (1114 aa)
	ENSLCAP00010026991	ELKS/RAB6-interacting/CAST family member 2. (1158 aa)
	Bsn	Bassoon (presynaptic cytomatrix protein) b. (3203 aa)
	PCLO	Piccolo presynaptic cytomatrix protein. (2421 aa)
	ENSLCAP00010024181	Zf-piccolo domain-containing protein. (494 aa)
	LOC108878291	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (323 aa)
	ENSLCAP00010024171	Zf-piccolo domain-containing protein. (383 aa)
	LOC108895615	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1184 aa)
	RIMS1	Regulating synaptic membrane exocytosis 1. (1479 aa)
	LOC108888998	Uncharacterized protein. (645 aa)
	LOC108888399	Uncharacterized protein. (679 aa)
	LOC108876722	Uncharacterized protein. (281 aa)
	stx1a	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (339 aa)
	ENSLCAP00010013902	Fer-1-like family member 4. (1842 aa)
	ENSLCAP00010013719	Syntaxin 11b, tandem duplicate 2; Belongs to the syntaxin family. (280 aa)
	adcy8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1240 aa)
	nectin1	Uncharacterized protein. (524 aa)
	Pclo	Piccolo presynaptic cytomatrix protein a. (3037 aa)
	ENSLCAP00010009042	Uncharacterized protein. (782 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bsn	ENSLCAP00010024181	ENSLCAP00010026866	ENSLCAP00010024181	Bassoon (presynaptic cytomatrix protein) b.	Zf-piccolo domain-containing protein.	0.417
Bsn	PCLO	ENSLCAP00010026866	ENSLCAP00010024248	Bassoon (presynaptic cytomatrix protein) b.	Piccolo presynaptic cytomatrix protein.	0.506
Bsn	Pclo	ENSLCAP00010026866	ENSLCAP00010009062	Bassoon (presynaptic cytomatrix protein) b.	Piccolo presynaptic cytomatrix protein a.	0.553
CDH2	ENSLCAP00010008847	ENSLCAP00010022145	ENSLCAP00010008847	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
CDH2	ENSLCAP00010036503	ENSLCAP00010022145	ENSLCAP00010036503	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.901
ENSLCAP00010007118	ENSLCAP00010013719	ENSLCAP00010007118	ENSLCAP00010013719	Uncharacterized protein.	Syntaxin 11b, tandem duplicate 2; Belongs to the syntaxin family.	0.454
ENSLCAP00010007118	ENSLCAP00010042231	ENSLCAP00010007118	ENSLCAP00010042231	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.454
ENSLCAP00010007118	ENSLCAP00010042238	ENSLCAP00010007118	ENSLCAP00010042238	Uncharacterized protein.	Syntaxin 11a.	0.454
ENSLCAP00010007118	ENSLCAP00010043777	ENSLCAP00010007118	ENSLCAP00010043777	Uncharacterized protein.	Regulating synaptic membrane exocytosis 1a.	0.670
ENSLCAP00010007118	ENSLCAP00010047160	ENSLCAP00010007118	ENSLCAP00010047160	Uncharacterized protein.	Syntaxin 1B; Belongs to the syntaxin family.	0.545
ENSLCAP00010007118	ENSLCAP00010047272	ENSLCAP00010007118	ENSLCAP00010047272	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.545
ENSLCAP00010007118	LOC108878291	ENSLCAP00010007118	ENSLCAP00010024176	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.545
ENSLCAP00010007118	LOC108878442	ENSLCAP00010007118	ENSLCAP00010051764	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.545
ENSLCAP00010007118	RIMS1	ENSLCAP00010007118	ENSLCAP00010020297	Uncharacterized protein.	Regulating synaptic membrane exocytosis 1.	0.670
ENSLCAP00010007118	RIMS2	ENSLCAP00010007118	ENSLCAP00010032352	Uncharacterized protein.	Regulating synaptic membrane exocytosis 2.	0.997
ENSLCAP00010007118	STX19	ENSLCAP00010007118	ENSLCAP00010049661	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.436
ENSLCAP00010007118	rims3	ENSLCAP00010007118	ENSLCAP00010034880	Uncharacterized protein.	C2 domain-containing protein.	0.670
ENSLCAP00010007118	rims4	ENSLCAP00010007118	ENSLCAP00010041905	Uncharacterized protein.	C2 domain-containing protein.	0.631
ENSLCAP00010007118	stx1a	ENSLCAP00010007118	ENSLCAP00010015512	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.545
ENSLCAP00010007118	stx4	ENSLCAP00010007118	ENSLCAP00010031138	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.545