(89 nodes) Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108883656	Ubiquitin-like domain-containing protein. (128 aa)
	LOC108890757	Uncharacterized protein. (980 aa)
	ENSLCAP00010008403	Uncharacterized protein; Belongs to the peptidase C14A family. (480 aa)
	sugt1	Uncharacterized protein. (324 aa)
	ENSLCAP00010007571	Mitogen-activated protein kinase. (391 aa)
	pstpip2	F-BAR domain-containing protein. (337 aa)
	rps27a	Ubiquitin-like domain-containing protein. (156 aa)
	tab2	Uncharacterized protein. (761 aa)
	LOC108882620	Mitogen-activated protein kinase. (363 aa)
	ENSLCAP00010003829	CARD domain-containing protein. (119 aa)
	LOC108899584	Uncharacterized protein. (205 aa)
	LOC108886424-2	Thioredoxin-like. (107 aa)
	LOC108886423-2	Thioredoxin-like. (107 aa)
	ENSLCAP00010001515	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. (444 aa)
	LOC108884881	BH4_2 domain-containing protein. (232 aa)
	panx1	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (418 aa)
	LOC108886423	Thioredoxin; Belongs to the thioredoxin family. (107 aa)
	LOC108886424	Thioredoxin; Belongs to the thioredoxin family. (107 aa)
	ENSLCAP00010000256	FIIND domain-containing protein. (1226 aa)
	LOC108879443	Arrestin_C domain-containing protein. (396 aa)
	ENSLCAP00010013020	Arrestin domain containing 2. (373 aa)
	LOC108890157	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	ENSLCAP00010013691	FIIND domain-containing protein. (268 aa)
	ENSLCAP00010013721	FIIND domain-containing protein. (255 aa)
	ENSLCAP00010014491	Mitogen-activated protein kinase. (361 aa)
	LOC108881637	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (581 aa)
	ENSLCAP00010015583	Uncharacterized protein; Belongs to the peptidase C14A family. (384 aa)
	ENSLCAP00010015606	Uncharacterized protein; Belongs to the peptidase C14A family. (395 aa)
	LOC108879443-2	Thioredoxin-interacting protein-like. (396 aa)
	LOC108882654	E3 ubiquitin-protein ligase. (887 aa)
	Tab1	TGF-beta activated kinase 1/MAP3K7 binding protein 1. (508 aa)
	LOC108886423-3	Thioredoxin-like. (107 aa)
	LOC108901401	Mitogen-activated protein kinase. (368 aa)
	LOC108901376	Mitogen-activated protein kinase. (364 aa)
	LOC108893387	Uncharacterized protein. (641 aa)
	casp2	Uncharacterized protein; Belongs to the peptidase C14A family. (468 aa)
	LOC108882672	Mitogen-activated protein kinase. (364 aa)
	bcl2	BH4_2 domain-containing protein. (229 aa)
	LOC108901902	TMEM189_B_dmain domain-containing protein. (283 aa)
	ENSLCAP00010023959	Mitogen-activated protein kinase kinase kinase 7. (606 aa)
	LOC108884718	Arrestin_C domain-containing protein. (409 aa)
	ENSLCAP00010028317	Uncharacterized protein. (269 aa)
	ENSLCAP00010030057	Uncharacterized protein. (255 aa)
	LOC108876789	Ubiquitin-like domain-containing protein. (128 aa)
	ENSLCAP00010033556	CCHC NOA-type domain-containing protein. (592 aa)
	ENSLCAP00010034456	BH4_2 domain-containing protein. (192 aa)
	LOC108902110	E3 ubiquitin-protein ligase. (866 aa)
	ENSLCAP00010034591	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
	Cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (920 aa)
	LOC108890485	TMEM189_B_dmain domain-containing protein. (275 aa)
	LOC108879443-3	Thioredoxin-interacting protein-like. (396 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (609 aa)
	hsp90ab1	HATPase_c domain-containing protein. (731 aa)
	Ubb	Ubiquitin B. (517 aa)
	nod1	Uncharacterized protein. (939 aa)
	LOC108885588	BH4_2 domain-containing protein. (221 aa)
	LOC108875352	Mitogen-activated protein kinase. (362 aa)
	LOC108885597	Uncharacterized protein. (712 aa)
	ENSLCAP00010042514	Protein kinase domain-containing protein. (427 aa)
	ENSLCAP00010042995	Arrestin_N domain-containing protein. (129 aa)
	Aamp	Angio-associated, migratory cell protein. (419 aa)
	ENSLCAP00010044755	Si:ch73-252p3.1. (1199 aa)
	ENSLCAP00010044762	Uncharacterized protein. (873 aa)
	pstpip1	Uncharacterized protein. (418 aa)
	LOC108878742	Arrestin_C domain-containing protein. (319 aa)
	ENSLCAP00010060068	Arrestin_C domain-containing protein. (366 aa)
	LOC108878789	Arrestin_C domain-containing protein. (378 aa)
	LOC108878056	Arrestin_C domain-containing protein. (449 aa)
	ENSLCAP00010060024	Arrestin_C domain-containing protein. (292 aa)
	ENSLCAP00010059884	Arrestin_C domain-containing protein. (306 aa)
	ENSLCAP00010059883	Arrestin_C domain-containing protein. (345 aa)
	casp9	Uncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
	arrdc3	Arrestin_C domain-containing protein. (412 aa)
	arrdc1	Uncharacterized protein. (453 aa)
	MAP2K6	Protein kinase domain-containing protein. (336 aa)
	LOC108886423-4	Thioredoxin-like. (107 aa)
	ENSLCAP00010055806	Uncharacterized protein. (802 aa)
	LOC108876848	Protein kinase domain-containing protein. (359 aa)
	LOC108877030	Uncharacterized protein. (420 aa)
	ripk2	Uncharacterized protein. (603 aa)
	Nme9	NME/NM23 family member 8; Belongs to the NDK family. (662 aa)
	ENSLCAP00010050445	NEMO domain-containing protein. (371 aa)
	tab3	Uncharacterized protein. (616 aa)
	LOC108882374	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (442 aa)
	LOC108894432	Arrestin_C domain-containing protein. (440 aa)
	LOC108895688	Arrestin_C domain-containing protein. (418 aa)
	LOC108876789-2	Ubiquitin-like domain-containing protein. (155 aa)
	ENSLCAP00010046779	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family. (520 aa)
	ENSLCAP00010046672	Ubiquitin-like domain-containing protein. (116 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aamp	nod1	ENSLCAP00010044604	ENSLCAP00010041009	Angio-associated, migratory cell protein.	Uncharacterized protein.	0.611
Cyld	ENSLCAP00010001515	ENSLCAP00010034631	ENSLCAP00010001515	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily.	0.470
Cyld	ENSLCAP00010023959	ENSLCAP00010034631	ENSLCAP00010023959	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Mitogen-activated protein kinase kinase kinase 7.	0.470
Cyld	ENSLCAP00010030057	ENSLCAP00010034631	ENSLCAP00010030057	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.527
Cyld	ENSLCAP00010033556	ENSLCAP00010034631	ENSLCAP00010033556	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	CCHC NOA-type domain-containing protein.	0.627
Cyld	ENSLCAP00010042514	ENSLCAP00010034631	ENSLCAP00010042514	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Protein kinase domain-containing protein.	0.437
Cyld	ENSLCAP00010046672	ENSLCAP00010034631	ENSLCAP00010046672	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Ubiquitin-like domain-containing protein.	0.776
Cyld	ENSLCAP00010050445	ENSLCAP00010034631	ENSLCAP00010050445	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	NEMO domain-containing protein.	0.866
Cyld	ENSLCAP00010055806	ENSLCAP00010034631	ENSLCAP00010055806	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.437
Cyld	LOC108876789	ENSLCAP00010034631	ENSLCAP00010031146	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Ubiquitin-like domain-containing protein.	0.729
Cyld	LOC108876789-2	ENSLCAP00010034631	ENSLCAP00010046809	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Ubiquitin-like domain-containing protein.	0.729
Cyld	LOC108883656	ENSLCAP00010034631	ENSLCAP00010046378	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Ubiquitin-like domain-containing protein.	0.729
Cyld	LOC108893387	ENSLCAP00010034631	ENSLCAP00010021098	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.527
Cyld	Ubb	ENSLCAP00010034631	ENSLCAP00010040766	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Ubiquitin B.	0.776
Cyld	ripk2	ENSLCAP00010034631	ENSLCAP00010051481	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.497
Cyld	rps27a	ENSLCAP00010034631	ENSLCAP00010005493	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Ubiquitin-like domain-containing protein.	0.884
Cyld	tab3	ENSLCAP00010034631	ENSLCAP00010049860	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.468
Cyld	traf6	ENSLCAP00010034631	ENSLCAP00010039774	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.838
ENSLCAP00010000256	ENSLCAP00010003829	ENSLCAP00010000256	ENSLCAP00010003829	FIIND domain-containing protein.	CARD domain-containing protein.	0.426
ENSLCAP00010000256	ENSLCAP00010015583	ENSLCAP00010000256	ENSLCAP00010015583	FIIND domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.430