117 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108898682	BZIP domain-containing protein. (328 aa)
	LOC108886018	Mothers against decapentaplegic homolog. (474 aa)
	LOC108887101	Uncharacterized protein; Belongs to the cyclin family. (723 aa)
	bambi	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
	mkx	Homeobox domain-containing protein. (363 aa)
	PARD3	Par-3 family cell polarity regulator. (1233 aa)
	ltbp1	Uncharacterized protein. (1554 aa)
	LOC108872996	Uncharacterized protein. (1260 aa)
	ENSLCAP00010057494	Uncharacterized protein. (1102 aa)
	LOC108886789	Uncharacterized protein. (284 aa)
	LOC108893685	Uncharacterized protein. (864 aa)
	LOC108885224	Homeobox domain-containing protein. (413 aa)
	SMURF2	E3 ubiquitin-protein ligase. (776 aa)
	ENSLCAP00010054904	Iroquois homeobox 7. (400 aa)
	ENSLCAP00010054716	Cingulin a. (1072 aa)
	LOC108878032	STIP1 homology and U box-containing protein 1-like. (290 aa)
	Zfyve9	Zinc finger, FYVE domain containing 9a. (1207 aa)
	Atp1b4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (376 aa)
	LOC108884588	Uncharacterized protein. (422 aa)
	ENSLCAP00010053720	Uncharacterized protein. (954 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	Arhgef18	Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1062 aa)
	ENSLCAP00010051264	Fibrillin 2b. (2720 aa)
	LOC108900362	Uncharacterized protein. (464 aa)
	LOC108900369	Homeobox domain-containing protein. (413 aa)
	ENSLCAP00010050805	Nuclear receptor corepressor 2. (2269 aa)
	tfdp1	Transcription factor. (413 aa)
	MEIS3	Homeobox domain-containing protein. (455 aa)
	LOC108872765	Integrin beta; Belongs to the integrin beta chain family. (809 aa)
	ENSLCAP00010048823	CYCLIN domain-containing protein; Belongs to the cyclin family. (597 aa)
	ENSLCAP00010048514	Cingulin b. (1045 aa)
	LOC108876789-2	Ubiquitin-like domain-containing protein. (155 aa)
	ENSLCAP00010046672	Ubiquitin-like domain-containing protein. (116 aa)
	LOC108883656	Ubiquitin-like domain-containing protein. (128 aa)
	LOC108882381	Homeobox domain-containing protein. (422 aa)
	smad3	Mothers against decapentaplegic homolog. (449 aa)
	ENSLCAP00010026208	Meis homeobox 2a. (401 aa)
	Cdk9	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (374 aa)
	Usp9x	Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2533 aa)
	STUB1	Uncharacterized protein. (290 aa)
	ENSLCAP00010022893	Retinoblastoma-like 1 (p107). (1081 aa)
	ENSLCAP00010022495	E2F transcription factor 4. (321 aa)
	smurf1	E3 ubiquitin-protein ligase. (729 aa)
	CCNK	Uncharacterized protein; Belongs to the cyclin family. (534 aa)
	snw1	SKIP_SNW domain-containing protein. (531 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	ENSLCAP00010019078	Cyclin T1. (544 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	itgb6	Integrin beta; Belongs to the integrin beta chain family. (806 aa)
	cbl	Uncharacterized protein. (958 aa)
	LOC108876160	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	ENSLCAP00010014495	Ubiquitin-like domain-containing protein. (92 aa)
	SMAD4	Mothers against decapentaplegic homolog. (524 aa)
	LTBP3	Uncharacterized protein. (1246 aa)
	smad7	Mothers against decapentaplegic homolog. (376 aa)
	LOC108896340	Mothers against decapentaplegic homolog. (616 aa)
	LOC108899258	c-SKI_SMAD_bind domain-containing protein. (694 aa)
	LOC108880948	Uncharacterized protein. (1418 aa)
	ENSLCAP00010010391	Neural precursor cell expressed, developmentally down-regulated 4-like. (1215 aa)
	ENSLCAP00010008517	Integrin beta; Belongs to the integrin beta chain family. (783 aa)
	LOC108898083	Peptidylprolyl isomerase. (79 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
	FBN1	Uncharacterized protein. (2811 aa)
	ENSLCAP00010000123	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (533 aa)
	ENSLCAP00010000430	E3 ubiquitin-protein ligase. (734 aa)
	ENSLCAP00010000673	Ubiquitin-like domain-containing protein. (96 aa)
	ENSLCAP00010001523	V-ski avian sarcoma viral oncogene homolog a. (720 aa)
	LOC108884929	Peptidylprolyl isomerase. (180 aa)
	ENSLCAP00010001596	Mothers against decapentaplegic homolog. (531 aa)
	LOC108881026	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
	Prkcz	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (573 aa)
	LOC108887878	Mothers against decapentaplegic homolog. (452 aa)
	ENSLCAP00010002138	F11 receptor, tandem duplicate 1. (292 aa)
	Trim33	Tripartite motif containing 33. (1241 aa)
	CDK19	Protein kinase domain-containing protein. (511 aa)
	LOC108883859	Homeobox domain-containing protein. (418 aa)
	rps27a	Ubiquitin-like domain-containing protein. (156 aa)
	LOC108877754	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (814 aa)
	strap	WD_REPEATS_REGION domain-containing protein. (350 aa)
	ENSLCAP00010006036	Homeobox domain-containing protein. (657 aa)
	LOC108875663	BZIP domain-containing protein. (331 aa)
	LOC108896283	Homeobox domain-containing protein. (321 aa)
	itgb5	Integrin beta; Belongs to the integrin beta chain family. (809 aa)
	cdk8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (500 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
	meis1	Uncharacterized protein. (421 aa)
	rnf111	RING-type domain-containing protein. (1030 aa)
	LOC108876789	Ubiquitin-like domain-containing protein. (128 aa)
	LOC108882197	Peptidylprolyl isomerase. (109 aa)
	fkbp1b	Peptidylprolyl isomerase. (108 aa)
	kxd1	KxDL domain-containing protein. (184 aa)
	LOC108882301	Meis_PKNOX_N domain-containing protein. (432 aa)
	LOC108878489	Mothers against decapentaplegic homolog. (467 aa)
	skil	c-SKI_SMAD_bind domain-containing protein. (772 aa)
	ccnq	CYCLIN domain-containing protein; Belongs to the cyclin family. (257 aa)
	men1	Uncharacterized protein. (625 aa)
	irx3	Homeobox domain-containing protein. (454 aa)
	irx5	Homeobox domain-containing protein. (452 aa)
	irx6	Homeobox domain-containing protein. (508 aa)
	sp1	Uncharacterized protein. (714 aa)
	furin	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (838 aa)
	ccnc	Uncharacterized protein; Belongs to the cyclin family. (283 aa)
	ENSLCAP00010038554	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
	meis2	Homeobox domain-containing protein. (490 aa)
	LOC108889059	Homeobox domain-containing protein. (498 aa)
	irx2	Homeobox domain-containing protein. (532 aa)
	LOC108885827	Homeobox domain-containing protein. (483 aa)
	Ubb	Ubiquitin B. (517 aa)
	ncor1	Uncharacterized protein. (2384 aa)
	ENSLCAP00010041862	Uncharacterized protein. (1241 aa)
	LOC108881978	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (647 aa)
	LOC108884387	Uncharacterized protein. (327 aa)
	LOC108876301	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (591 aa)
	tgfb3	Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
	ENSLCAP00010042788	Integrin beta; Belongs to the integrin beta chain family. (752 aa)
	ldlrad4	Uncharacterized protein. (323 aa)
	LOC108872574	Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arhgef18	ENSLCAP00010048514	ENSLCAP00010051352	ENSLCAP00010048514	Rho/rac guanine nucleotide exchange factor (GEF) 18b.	Cingulin b.	0.454
Arhgef18	ENSLCAP00010054716	ENSLCAP00010051352	ENSLCAP00010054716	Rho/rac guanine nucleotide exchange factor (GEF) 18b.	Cingulin a.	0.536
Arhgef18	LOC108880948	ENSLCAP00010051352	ENSLCAP00010010533	Rho/rac guanine nucleotide exchange factor (GEF) 18b.	Uncharacterized protein.	0.417
Arhgef18	PARD3	ENSLCAP00010051352	ENSLCAP00010059555	Rho/rac guanine nucleotide exchange factor (GEF) 18b.	Par-3 family cell polarity regulator.	0.417
Atp1b4	snw1	ENSLCAP00010053938	ENSLCAP00010021658	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SKIP_SNW domain-containing protein.	0.780
CCNK	CDK19	ENSLCAP00010021836	ENSLCAP00010004203	Uncharacterized protein; Belongs to the cyclin family.	Protein kinase domain-containing protein.	0.772
CCNK	Cdk9	ENSLCAP00010021836	ENSLCAP00010025072	Uncharacterized protein; Belongs to the cyclin family.	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	0.964
CCNK	ENSLCAP00010001596	ENSLCAP00010021836	ENSLCAP00010001596	Uncharacterized protein; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.516
CCNK	ENSLCAP00010019078	ENSLCAP00010021836	ENSLCAP00010019078	Uncharacterized protein; Belongs to the cyclin family.	Cyclin T1.	0.674
CCNK	ENSLCAP00010048823	ENSLCAP00010021836	ENSLCAP00010048823	Uncharacterized protein; Belongs to the cyclin family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.674
CCNK	LOC108887101	ENSLCAP00010021836	ENSLCAP00010060350	Uncharacterized protein; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the cyclin family.	0.674
CCNK	LOC108896340	ENSLCAP00010021836	ENSLCAP00010011045	Uncharacterized protein; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.518
CCNK	SMAD4	ENSLCAP00010021836	ENSLCAP00010013760	Uncharacterized protein; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.516
CCNK	ccnc	ENSLCAP00010021836	ENSLCAP00010038519	Uncharacterized protein; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the cyclin family.	0.859
CCNK	cdk8	ENSLCAP00010021836	ENSLCAP00010026887	Uncharacterized protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.772
CCNK	sp1	ENSLCAP00010021836	ENSLCAP00010036320	Uncharacterized protein; Belongs to the cyclin family.	Uncharacterized protein.	0.624
CDK19	CCNK	ENSLCAP00010004203	ENSLCAP00010021836	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the cyclin family.	0.772
CDK19	Cdk9	ENSLCAP00010004203	ENSLCAP00010025072	Protein kinase domain-containing protein.	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	0.652
CDK19	ENSLCAP00010001596	ENSLCAP00010004203	ENSLCAP00010001596	Protein kinase domain-containing protein.	Mothers against decapentaplegic homolog.	0.465
CDK19	ENSLCAP00010019078	ENSLCAP00010004203	ENSLCAP00010019078	Protein kinase domain-containing protein.	Cyclin T1.	0.571