121 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cdc20b	WD_REPEATS_REGION domain-containing protein. (387 aa)
	PSMD3	PCI domain-containing protein. (534 aa)
	LOC108883827	WD_REPEATS_REGION domain-containing protein. (487 aa)
	psmd5	Uncharacterized protein. (504 aa)
	psmc4	AAA domain-containing protein; Belongs to the AAA ATPase family. (417 aa)
	ENSLCAP00010004085	Proteasome subunit beta 6. (497 aa)
	anapc10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)
	psmd2	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
	Psme1	Proteasome activator subunit 1. (265 aa)
	rps27a	Ubiquitin-like domain-containing protein. (156 aa)
	psma1	Proteasome subunit alpha type. (262 aa)
	LOC108874380	Uncharacterized protein. (256 aa)
	ENSLCAP00010006513	Uncharacterized protein. (348 aa)
	LOC108883014	Proteasome subunit alpha type. (261 aa)
	LOC108891223	HORMA domain-containing protein. (202 aa)
	LOC108884115	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (427 aa)
	psmc1	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	psmd13	PCI domain-containing protein. (399 aa)
	LOC108895836	Proteasome endopeptidase complex. (295 aa)
	Psmd10	Proteasome 26S subunit, non-ATPase 10. (228 aa)
	psmd8	PCI domain-containing protein. (290 aa)
	bicra	GLTSCR1 domain-containing protein. (1918 aa)
	cdc26	Uncharacterized protein. (95 aa)
	ENSLCAP00010013668	PROTEASOME_ALPHA_1 domain-containing protein. (104 aa)
	cdk2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	cdc23	Uncharacterized protein. (600 aa)
	LOC108883947	Uncharacterized protein. (355 aa)
	LOC108883948	Proteasome subunit beta. (271 aa)
	psmd14	MPN domain-containing protein. (310 aa)
	LOC108873252	PCI domain-containing protein. (520 aa)
	ube2s	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (236 aa)
	LOC108881898	Proteasome subunit beta. (216 aa)
	LOC108888425	Uncharacterized protein. (217 aa)
	LOC108888423	Proteasome subunit beta. (275 aa)
	LOC108888424	Proteasome subunit beta. (275 aa)
	psmd6	PCI domain-containing protein. (397 aa)
	psmb3	Proteasome subunit beta. (205 aa)
	anapc11	RING-type domain-containing protein. (84 aa)
	psma8	Proteasome subunit alpha type. (251 aa)
	psmf1	Uncharacterized protein. (277 aa)
	cdc16	TPR_REGION domain-containing protein. (620 aa)
	Anapc2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (872 aa)
	LOC108900731	F-box domain-containing protein. (421 aa)
	psmd1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
	ENSLCAP00010024363	BUB1 mitotic checkpoint serine/threonine kinase Bb. (407 aa)
	PSME3	Proteasome activator subunit 3. (272 aa)
	MAD2L1	Mitotic spindle assembly checkpoint protein MAD2A-like. (202 aa)
	psma5	Proteasome subunit alpha type. (241 aa)
	Psmc6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (421 aa)
	Psmb7	Proteasome subunit beta. (305 aa)
	ENSLCAP00010027853	Proteasome 26S subunit, non-ATPase 7. (337 aa)
	Cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (331 aa)
	cdc20	WD_REPEATS_REGION domain-containing protein. (502 aa)
	skp1	Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
	ENSLCAP00010029805	Proteasome 26S subunit, non-ATPase 11b. (439 aa)
	Gltscr1l	BRD4 interacting chromatin remodeling complex associated protein like. (663 aa)
	LOC108876789	Ubiquitin-like domain-containing protein. (128 aa)
	LOC108879927	Uncharacterized protein. (184 aa)
	ENSLCAP00010031434	Proteasome subunit beta11b. (302 aa)
	LOC108889618	VWFA domain-containing protein. (375 aa)
	kxd1	KxDL domain-containing protein. (184 aa)
	anapc4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (804 aa)
	LOC108883136	Proteasome subunit alpha type. (246 aa)
	psmc5	AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa)
	psmc2	AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
	psme4	Uncharacterized protein. (1847 aa)
	FZR1	WD_REPEATS_REGION domain-containing protein. (496 aa)
	psma2	Proteasome subunit alpha type. (234 aa)
	LOC108898553	Uncharacterized protein. (256 aa)
	PSMD11	Proteasome 26S subunit, non-ATPase 11. (461 aa)
	fam89a	Uncharacterized protein. (178 aa)
	Ubb	Ubiquitin B. (517 aa)
	PSMA4	Proteasome subunit alpha type. (261 aa)
	fbxo5	Uncharacterized protein. (462 aa)
	ENSLCAP00010042538	Anaphase promoting complex subunit 1. (1892 aa)
	cdc27	Uncharacterized protein. (808 aa)
	ENSLCAP00010043392	Rpn3_C domain-containing protein. (104 aa)
	anapc16	Uncharacterized protein. (108 aa)
	LOC108883136-2	Proteasome subunit alpha type-6-like. (246 aa)
	LOC108894001	Uncharacterized protein. (189 aa)
	FBXO43	F-box protein 43. (583 aa)
	ENSLCAP00010044371	Uncharacterized protein. (509 aa)
	cdk2-2	Cyclin-dependent kinase 2. (298 aa)
	LOC108881898-2	Proteasome subunit beta type-9. (216 aa)
	LOC108881905	Uncharacterized protein. (217 aa)
	LOC108881904	Proteasome subunit beta. (275 aa)
	LOC108881903	Proteasome subunit beta. (275 aa)
	nek2	Protein kinase domain-containing protein. (445 aa)
	anapc5	Uncharacterized protein. (773 aa)
	bub3	WD_REPEATS_REGION domain-containing protein. (326 aa)
	anapc15	Uncharacterized protein. (122 aa)
	LOC108877696	Proteasome subunit beta. (278 aa)
	LOC108883656	Ubiquitin-like domain-containing protein. (128 aa)
	psmb2	Proteasome subunit beta. (199 aa)
	ENSLCAP00010046672	Ubiquitin-like domain-containing protein. (116 aa)
	psmb4	Proteasome subunit beta; Belongs to the peptidase T1B family. (262 aa)
	LOC108876789-2	Ubiquitin-like domain-containing protein. (155 aa)
	ccna1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (416 aa)
	Psma6	Proteasome subunit alpha type. (204 aa)
	ENSLCAP00010048462	Aurora kinase B; Belongs to the protein kinase superfamily. (335 aa)
	LOC108888868	VWFA domain-containing protein. (372 aa)
	ccnb1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (404 aa)
	ENSLCAP00010049581	Uncharacterized protein. (1795 aa)
	ube2c	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
	ENSLCAP00010053862	Uncharacterized protein. (205 aa)
	Psmd12	Proteasome 26S subunit, non-ATPase 12. (456 aa)
	LOC108881353	WD_REPEATS_REGION domain-containing protein. (495 aa)
	cul1	CULLIN_2 domain-containing protein; Belongs to the cullin family. (776 aa)
	rb1	Uncharacterized protein. (913 aa)
	ENSLCAP00010055640	annotation not available (277 aa)
	ENSLCAP00010055815	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (285 aa)
	tm7sf3	DUF4203 domain-containing protein. (565 aa)
	ccna2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (436 aa)
	Psmc3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (436 aa)
	Psmb1	Proteasome subunit beta. (243 aa)
	psme2	Uncharacterized protein. (341 aa)
	LOC108889222	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
	psma3	Proteasome subunit alpha type. (255 aa)
	anapc7	Uncharacterized protein. (574 aa)
	ENSLCAP00010060028	Proteasome activator subunit 3. (272 aa)
	psmd9	PDZ domain-containing protein. (212 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Anapc2	Cdc20b	ENSLCAP00010023649	ENSLCAP00010000857	Anaphase promoting complex subunit 2; Belongs to the cullin family.	WD_REPEATS_REGION domain-containing protein.	0.984
Anapc2	Cdk1	ENSLCAP00010023649	ENSLCAP00010028139	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.807
Anapc2	ENSLCAP00010024363	ENSLCAP00010023649	ENSLCAP00010024363	Anaphase promoting complex subunit 2; Belongs to the cullin family.	BUB1 mitotic checkpoint serine/threonine kinase Bb.	0.959
Anapc2	ENSLCAP00010029805	ENSLCAP00010023649	ENSLCAP00010029805	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Proteasome 26S subunit, non-ATPase 11b.	0.588
Anapc2	ENSLCAP00010031434	ENSLCAP00010023649	ENSLCAP00010031434	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Proteasome subunit beta11b.	0.436
Anapc2	ENSLCAP00010042538	ENSLCAP00010023649	ENSLCAP00010042538	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Anaphase promoting complex subunit 1.	0.999
Anapc2	ENSLCAP00010046672	ENSLCAP00010023649	ENSLCAP00010046672	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.831
Anapc2	ENSLCAP00010053862	ENSLCAP00010023649	ENSLCAP00010053862	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Uncharacterized protein.	0.868
Anapc2	ENSLCAP00010055640	ENSLCAP00010023649	ENSLCAP00010055640	Anaphase promoting complex subunit 2; Belongs to the cullin family.	annotation not available	0.471
Anapc2	ENSLCAP00010055815	ENSLCAP00010023649	ENSLCAP00010055815	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.471
Anapc2	FZR1	ENSLCAP00010023649	ENSLCAP00010035104	Anaphase promoting complex subunit 2; Belongs to the cullin family.	WD_REPEATS_REGION domain-containing protein.	0.986
Anapc2	Gltscr1l	ENSLCAP00010023649	ENSLCAP00010030117	Anaphase promoting complex subunit 2; Belongs to the cullin family.	BRD4 interacting chromatin remodeling complex associated protein like.	0.949
Anapc2	LOC108876789	ENSLCAP00010023649	ENSLCAP00010031146	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.814
Anapc2	LOC108876789-2	ENSLCAP00010023649	ENSLCAP00010046809	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.814
Anapc2	LOC108879927	ENSLCAP00010023649	ENSLCAP00010031373	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Uncharacterized protein.	0.868
Anapc2	LOC108881353	ENSLCAP00010023649	ENSLCAP00010054207	Anaphase promoting complex subunit 2; Belongs to the cullin family.	WD_REPEATS_REGION domain-containing protein.	0.986
Anapc2	LOC108881903	ENSLCAP00010023649	ENSLCAP00010044848	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Proteasome subunit beta.	0.444
Anapc2	LOC108883656	ENSLCAP00010023649	ENSLCAP00010046378	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.814
Anapc2	LOC108883827	ENSLCAP00010023649	ENSLCAP00010002941	Anaphase promoting complex subunit 2; Belongs to the cullin family.	WD_REPEATS_REGION domain-containing protein.	0.986
Anapc2	LOC108883947	ENSLCAP00010023649	ENSLCAP00010015562	Anaphase promoting complex subunit 2; Belongs to the cullin family.	Uncharacterized protein.	0.436