108 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gnb1	WD_REPEATS_REGION domain-containing protein. (340 aa)
	LOC108893375	WD_REPEATS_REGION domain-containing protein. (350 aa)
	LOC108900347	Uncharacterized protein; Belongs to the potassium channel family. (538 aa)
	LOC108883323	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	ENSLCAP00010002252	Sorting nexin 19a. (896 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2188 aa)
	LOC108872939	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
	LOC108874116	Uncharacterized protein. (354 aa)
	ENSLCAP00010005935	Guanine nucleotide binding protein (G protein), q polypeptide. (374 aa)
	ENSLCAP00010006438	CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (451 aa)
	LOC108886198	Uncharacterized protein. (368 aa)
	acsl3	AMP-binding domain-containing protein. (738 aa)
	Gng10	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (113 aa)
	gnb3	WD_REPEATS_REGION domain-containing protein. (340 aa)
	acsl4	AMP-binding domain-containing protein. (712 aa)
	ENSLCAP00010010953	Calcium channel, voltage-dependent, alpha 2/delta subunit 1a. (1065 aa)
	ENSLCAP00010011079	BTB domain-containing protein; Belongs to the potassium channel family. (449 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	LOC108875732	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	ENSLCAP00010011771	Calcium channel, voltage-dependent, alpha 2/delta subunit 2a. (977 aa)
	LOC108899241	WD_REPEATS_REGION domain-containing protein. (340 aa)
	LOC108901984	Uncharacterized protein. (536 aa)
	snx19	Uncharacterized protein. (981 aa)
	ADRA2C	Adrenoceptor alpha 2C. (447 aa)
	slc2a2	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (551 aa)
	LOC108878959	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	LOC108889971	Uncharacterized protein. (355 aa)
	LOC108893936	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	ENSLCAP00010017978	Calcium channel, voltage-dependent, R type, alpha 1E subunit b. (2227 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (643 aa)
	LOC108883401	Uncharacterized protein; Belongs to the protein kinase superfamily. (387 aa)
	gnb5	WD_REPEATS_REGION domain-containing protein. (408 aa)
	LOC108889872	BTB domain-containing protein; Belongs to the potassium channel family. (832 aa)
	LOC108888080	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa)
	ENSLCAP00010022375	Adrenoceptor alpha 2A. (384 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1152 aa)
	LOC108875137	VWFA domain-containing protein. (1077 aa)
	ENSLCAP00010025093	Calcium channel, voltage-dependent, alpha 2/delta subunit 2b. (1063 aa)
	ENSLCAP00010025745	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (367 aa)
	ENSLCAP00010026528	Ras-GEF domain-containing protein. (448 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1244 aa)
	ENSLCAP00010029625	BTB domain-containing protein; Belongs to the potassium channel family. (513 aa)
	ENSLCAP00010029659	ZP domain-containing protein. (413 aa)
	LOC108880306	ZP domain-containing protein. (371 aa)
	LOC108880480	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	LOC108874970	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	ENSLCAP00010031042	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1843 aa)
	LOC108874918	Uncharacterized protein. (402 aa)
	Gngt2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	LOC108883509	ZP domain-containing protein. (462 aa)
	LOC108898475	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	LOC108875401	Uncharacterized protein. (359 aa)
	ENSLCAP00010032878	Acyl-CoA synthetase long chain family member 3b. (716 aa)
	ENSLCAP00010032965	Adrenoceptor alpha 2C. (466 aa)
	ENSLCAP00010033852	Si:dkey-211g8.9. (295 aa)
	ENSLCAP00010033984	Uncharacterized protein. (89 aa)
	GNG13	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa)
	LOC108902169	ZP domain-containing protein. (389 aa)
	ENSLCAP00010035270	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1712 aa)
	Itpr2	Inositol 1,4,5-trisphosphate receptor, type 2. (2658 aa)
	LOC108875732-2	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like. (71 aa)
	ENSLCAP00010035941	Ion_trans domain-containing protein. (434 aa)
	ENSLCAP00010036780	Ca_chan_IQ domain-containing protein. (2330 aa)
	ENSLCAP00010037712	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1636 aa)
	Adcy5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1184 aa)
	LOC108893282	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1265 aa)
	Kcnj11	Potassium inwardly-rectifying channel, subfamily J, member 11. (406 aa)
	ENSLCAP00010039935	Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. (2177 aa)
	abcc8	Uncharacterized protein. (1598 aa)
	LOC108876515	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1182 aa)
	LOC108876767	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (81 aa)
	ENSLCAP00010042228	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2112 aa)
	LOC108883636	Uncharacterized protein. (996 aa)
	adcy6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1210 aa)
	LOC108883268	SH3 domain-containing protein. (628 aa)
	LOC108889838	Uncharacterized protein. (355 aa)
	gng3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	LOC108881277	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5. (68 aa)
	kcns3	BTB domain-containing protein; Belongs to the potassium channel family. (492 aa)
	THAP1	THAP domain containing 1. (197 aa)
	ENSLCAP00010047037	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1737 aa)
	ENSLCAP00010048046	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2127 aa)
	ENSLCAP00010048362	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (104 aa)
	gnb4	WD_REPEATS_REGION domain-containing protein. (343 aa)
	Marcks	Myristoylated alanine-rich protein kinase C substrate a. (225 aa)
	ENSLCAP00010049689	Inositol 1,4,5-trisphosphate receptor, type 1a. (2745 aa)
	LOC108876959	WD_REPEATS_REGION domain-containing protein. (395 aa)
	Rapgefl1	Rap guanine nucleotide exchange factor (GEF)-like 1. (381 aa)
	cacnb2	SH3 domain-containing protein. (703 aa)
	LOC108886373	Uncharacterized protein. (868 aa)
	LOC108887531	WD_REPEATS_REGION domain-containing protein. (342 aa)
	ENSLCAP00010053135	THAP-type domain-containing protein. (579 aa)
	gng2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	ENSLCAP00010053512	Inositol 1,4,5-trisphosphate receptor, type 3. (2210 aa)
	rapgef4	Uncharacterized protein. (1025 aa)
	gcg	Uncharacterized protein. (123 aa)
	LOC108888462	G protein gamma domain-containing protein. (67 aa)
	LOC108902709	Uncharacterized protein; Belongs to the protein kinase superfamily. (377 aa)
	ENSLCAP00010056471	Inositol 1,4,5-trisphosphate receptor, type 1b. (2604 aa)
	kcnb1	BTB domain-containing protein; Belongs to the potassium channel family. (800 aa)
	ENSLCAP00010057681	Calcium channel, voltage-dependent, R type, alpha 1E subunit a. (2142 aa)
	LOC108881409	Uncharacterized protein. (369 aa)
	LOC108881412	Uncharacterized protein. (402 aa)
	ENSLCAP00010058693	Ion_trans domain-containing protein. (378 aa)
	LOC108878372	Uncharacterized protein. (354 aa)
	ENSLCAP00010060883	Uncharacterized protein. (382 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA2C	GNG13	ENSLCAP00010015649	ENSLCAP00010034564	Adrenoceptor alpha 2C.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.457
ADRA2C	GNG4	ENSLCAP00010015649	ENSLCAP00010011420	Adrenoceptor alpha 2C.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.556
ADRA2C	Gng10	ENSLCAP00010015649	ENSLCAP00010008222	Adrenoceptor alpha 2C.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.457
ADRA2C	Gngt2	ENSLCAP00010015649	ENSLCAP00010031685	Adrenoceptor alpha 2C.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.463
ADRA2C	LOC108876767	ENSLCAP00010015649	ENSLCAP00010040695	Adrenoceptor alpha 2C.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.436
ADRA2C	LOC108876959	ENSLCAP00010015649	ENSLCAP00010049893	Adrenoceptor alpha 2C.	WD_REPEATS_REGION domain-containing protein.	0.538
ADRA2C	LOC108893375	ENSLCAP00010015649	ENSLCAP00010001751	Adrenoceptor alpha 2C.	WD_REPEATS_REGION domain-containing protein.	0.471
ADRA2C	LOC108893936	ENSLCAP00010015649	ENSLCAP00010017912	Adrenoceptor alpha 2C.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.436
ADRA2C	LOC108899241	ENSLCAP00010015649	ENSLCAP00010012114	Adrenoceptor alpha 2C.	WD_REPEATS_REGION domain-containing protein.	0.457
ADRA2C	gnb1	ENSLCAP00010015649	ENSLCAP00010000510	Adrenoceptor alpha 2C.	WD_REPEATS_REGION domain-containing protein.	0.457
ADRA2C	gnb4	ENSLCAP00010015649	ENSLCAP00010049037	Adrenoceptor alpha 2C.	WD_REPEATS_REGION domain-containing protein.	0.457
ADRA2C	gnb5	ENSLCAP00010015649	ENSLCAP00010020122	Adrenoceptor alpha 2C.	WD_REPEATS_REGION domain-containing protein.	0.538
ADRA2C	gng2	ENSLCAP00010015649	ENSLCAP00010053167	Adrenoceptor alpha 2C.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.556
ADRA2C	gng3	ENSLCAP00010015649	ENSLCAP00010044278	Adrenoceptor alpha 2C.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.438
Adcy5	ENSLCAP00010048362	ENSLCAP00010037840	ENSLCAP00010048362	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.785
Adcy5	GNG13	ENSLCAP00010037840	ENSLCAP00010034564	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.827
Adcy5	GNG4	ENSLCAP00010037840	ENSLCAP00010011420	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.794
Adcy5	GNG5	ENSLCAP00010037840	ENSLCAP00010032592	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.780
Adcy5	Gng10	ENSLCAP00010037840	ENSLCAP00010008222	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.823
Adcy5	Gngt2	ENSLCAP00010037840	ENSLCAP00010031685	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.818