46 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108891507	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (414 aa)
	vcp	Uncharacterized protein. (872 aa)
	LOC108892171	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (578 aa)
	spata5l1	Uncharacterized protein. (776 aa)
	otud7b	Uncharacterized protein. (927 aa)
	SPATA5	Uncharacterized protein. (903 aa)
	ENSLCAP00010003080	OTU deubiquitinase 3. (334 aa)
	ENSLCAP00010004526	OTU domain-containing protein. (253 aa)
	rps27a	Ubiquitin-like domain-containing protein. (156 aa)
	LOC108887909	RING-type domain-containing protein. (362 aa)
	ENSLCAP00010009450	APC_N_CC domain-containing protein. (163 aa)
	ENSLCAP00010012913	Motor neuron and pancreas homeobox 2b. (243 aa)
	ENSLCAP00010012920	Uncharacterized protein. (67 aa)
	Apc	APC_N_CC domain-containing protein. (233 aa)
	vcpip1	OTU domain-containing protein. (1176 aa)
	ENSLCAP00010013378	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (623 aa)
	yod1	Uncharacterized protein. (301 aa)
	LOC108897292	Uncharacterized protein. (558 aa)
	LOC108879980	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (380 aa)
	ENSLCAP00010016623	TNFAIP3 interacting protein 1. (547 aa)
	ripk1	Uncharacterized protein. (684 aa)
	otub1	Ubiquitin thioesterase. (280 aa)
	rnf13	RING-type domain-containing protein. (384 aa)
	otud7a	Uncharacterized protein. (964 aa)
	LOC108885429	Uncharacterized protein; Belongs to the AAA ATPase family. (841 aa)
	LOC108897299	Uncharacterized protein. (762 aa)
	ENSLCAP00010026940	Tumor necrosis factor, alpha-induced protein 3. (777 aa)
	ENSLCAP00010027384	Adenomatosis polyposis coli 2. (2057 aa)
	Cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (331 aa)
	LOC108876789	Ubiquitin-like domain-containing protein. (128 aa)
	kxd1	KxDL domain-containing protein. (184 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (609 aa)
	nod1	Uncharacterized protein. (939 aa)
	Zranb1	Zinc finger, RAN-binding domain containing 1a. (708 aa)
	ENSLCAP00010046200	APC_N_CC domain-containing protein. (236 aa)
	LOC108883656	Ubiquitin-like domain-containing protein. (128 aa)
	ENSLCAP00010046672	Ubiquitin-like domain-containing protein. (116 aa)
	LOC108876789-2	Ubiquitin-like domain-containing protein. (155 aa)
	OTUB2	OTU domain-containing protein. (230 aa)
	ENSLCAP00010048326	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (639 aa)
	ENSLCAP00010050445	NEMO domain-containing protein. (371 aa)
	ripk2	Uncharacterized protein. (603 aa)
	Guf1	Tr-type G domain-containing protein. (55 aa)
	LOC108893504	RING-type domain-containing protein. (402 aa)
	Ubb	Ubiquitin B. (517 aa)
	Otud5	OTU deubiquitinase 5a. (564 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Apc	ENSLCAP00010026940	ENSLCAP00010013206	ENSLCAP00010026940	APC_N_CC domain-containing protein.	Tumor necrosis factor, alpha-induced protein 3.	0.425
Apc	ENSLCAP00010027384	ENSLCAP00010013206	ENSLCAP00010027384	APC_N_CC domain-containing protein.	Adenomatosis polyposis coli 2.	0.989
Apc	ENSLCAP00010046672	ENSLCAP00010013206	ENSLCAP00010046672	APC_N_CC domain-containing protein.	Ubiquitin-like domain-containing protein.	0.479
Apc	LOC108897299	ENSLCAP00010013206	ENSLCAP00010026143	APC_N_CC domain-containing protein.	Uncharacterized protein.	0.527
Apc	Ubb	ENSLCAP00010013206	ENSLCAP00010040766	APC_N_CC domain-containing protein.	Ubiquitin B.	0.479
Apc	Zranb1	ENSLCAP00010013206	ENSLCAP00010045986	APC_N_CC domain-containing protein.	Zinc finger, RAN-binding domain containing 1a.	0.527
Apc	otud7a	ENSLCAP00010013206	ENSLCAP00010022713	APC_N_CC domain-containing protein.	Uncharacterized protein.	0.425
Apc	otud7b	ENSLCAP00010013206	ENSLCAP00010002472	APC_N_CC domain-containing protein.	Uncharacterized protein.	0.425
Apc	vcpip1	ENSLCAP00010013206	ENSLCAP00010013236	APC_N_CC domain-containing protein.	OTU domain-containing protein.	0.425
Cdk1	ENSLCAP00010046672	ENSLCAP00010028139	ENSLCAP00010046672	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Ubiquitin-like domain-containing protein.	0.488
Cdk1	LOC108876789	ENSLCAP00010028139	ENSLCAP00010031146	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Ubiquitin-like domain-containing protein.	0.479
Cdk1	LOC108876789-2	ENSLCAP00010028139	ENSLCAP00010046809	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Ubiquitin-like domain-containing protein.	0.479
Cdk1	LOC108879980	ENSLCAP00010028139	ENSLCAP00010016052	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.681
Cdk1	LOC108883656	ENSLCAP00010028139	ENSLCAP00010046378	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Ubiquitin-like domain-containing protein.	0.479
Cdk1	Ubb	ENSLCAP00010028139	ENSLCAP00010040766	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Ubiquitin B.	0.488
Cdk1	rps27a	ENSLCAP00010028139	ENSLCAP00010005493	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Ubiquitin-like domain-containing protein.	0.602
Cdk1	vcpip1	ENSLCAP00010028139	ENSLCAP00010013236	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	OTU domain-containing protein.	0.494
ENSLCAP00010003080	ENSLCAP00010046672	ENSLCAP00010003080	ENSLCAP00010046672	OTU deubiquitinase 3.	Ubiquitin-like domain-containing protein.	0.638
ENSLCAP00010003080	LOC108891507	ENSLCAP00010003080	ENSLCAP00010057546	OTU deubiquitinase 3.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.665
ENSLCAP00010003080	LOC108897292	ENSLCAP00010003080	ENSLCAP00010015009	OTU deubiquitinase 3.	Uncharacterized protein.	0.665