STRINGSTRING
trub1 trub1 ENSLCAP00010051031 ENSLCAP00010051031 LOC108873640-3 LOC108873640-3 ENSLCAP00010050501 ENSLCAP00010050501 ENSLCAP00010050488 ENSLCAP00010050488 LOC108877208 LOC108877208 ENSLCAP00010050470 ENSLCAP00010050470 LOC108902035 LOC108902035 rfc3 rfc3 LOC108886681 LOC108886681 pif1 pif1 dkc1 dkc1 ccna1 ccna1 H2AZ1 H2AZ1 Gar1 Gar1 ENSLCAP00010046546 ENSLCAP00010046546 LOC108877697 LOC108877697 ENSLCAP00010045292 ENSLCAP00010045292 LOC108881908 LOC108881908 chtf8 chtf8 ENSLCAP00010044578 ENSLCAP00010044578 ENSLCAP00010044467 ENSLCAP00010044467 cdk2-2 cdk2-2 ten1 ten1 ENSLCAP00010042999 ENSLCAP00010042999 ENSLCAP00010042987 ENSLCAP00010042987 ENSLCAP00010042963 ENSLCAP00010042963 smarca5 smarca5 LOC108877712 LOC108877712 prim1 prim1 ENSLCAP00010041630 ENSLCAP00010041630 LOC108873639 LOC108873639 LOC108900816 LOC108900816 ruvbl1 ruvbl1 cenpw cenpw LOC108892908 LOC108892908 Ruvbl2 Ruvbl2 cenpi cenpi wrap53 wrap53 Rfc5 Rfc5 LOC108900468 LOC108900468 ENSLCAP00010032564 ENSLCAP00010032564 ENSLCAP00010029557 ENSLCAP00010029557 ENSLCAP00010029552 ENSLCAP00010029552 ENSLCAP00010029546 ENSLCAP00010029546 ENSLCAP00010029538 ENSLCAP00010029538 ENSLCAP00010029533 ENSLCAP00010029533 ENSLCAP00010029519 ENSLCAP00010029519 ENSLCAP00010029487 ENSLCAP00010029487 ENSLCAP00010029462 ENSLCAP00010029462 ENSLCAP00010029451 ENSLCAP00010029451 PPP6C PPP6C LOC108873640-2 LOC108873640-2 ENSLCAP00010026604 ENSLCAP00010026604 LOC108901759-2 LOC108901759-2 ENSLCAP00010026444 ENSLCAP00010026444 ENSLCAP00010026416 ENSLCAP00010026416 ENSLCAP00010026411 ENSLCAP00010026411 LOC108901759 LOC108901759 LOC108873640 LOC108873640 ENSLCAP00010026293 ENSLCAP00010026293 ankrd28 ankrd28 rpa2 rpa2 LOC108893335 LOC108893335 ENSLCAP00010022932 ENSLCAP00010022932 Cenpq Cenpq ENSLCAP00010021619 ENSLCAP00010021619 LOC108890174 LOC108890174 exd2 exd2 Rfc2 Rfc2 ENSLCAP00010020841 ENSLCAP00010020841 ENSLCAP00010020695 ENSLCAP00010020695 fen1 fen1 ENSLCAP00010019751 ENSLCAP00010019751 RCBTB1 RCBTB1 LOC108901361 LOC108901361 ENSLCAP00010018791 ENSLCAP00010018791 ENSLCAP00010018773 ENSLCAP00010018773 ENSLCAP00010018730 ENSLCAP00010018730 ENSLCAP00010018208 ENSLCAP00010018208 LOC108901366 LOC108901366 ENSLCAP00010018196 ENSLCAP00010018196 ENSLCAP00010017650 ENSLCAP00010017650 stn1 stn1 ENSLCAP00010000450 ENSLCAP00010000450 Pold1 Pold1 Pot1 Pot1 Rfc1 Rfc1 ENSLCAP00010002355 ENSLCAP00010002355 ENSLCAP00010002534 ENSLCAP00010002534 LOC108875967 LOC108875967 lig1 lig1 ENSLCAP00010006675 ENSLCAP00010006675 pold3 pold3 pcna pcna pola2 pola2 cenpn cenpn cenpk cenpk LOC108876221 LOC108876221 tert tert LOC108886744 LOC108886744 pold2 pold2 LOC108892335 LOC108892335 ENSLCAP00010054492 ENSLCAP00010054492 Terf2 Terf2 ENSLCAP00010055044 ENSLCAP00010055044 mis18a mis18a pold4 pold4 cenpm cenpm ENSLCAP00010055640 ENSLCAP00010055640 rfc4 rfc4 ENSLCAP00010055689 ENSLCAP00010055689 ENSLCAP00010055815 ENSLCAP00010055815 chtf18 chtf18 Dna2 Dna2 ccna2 ccna2 ENSLCAP00010057290 ENSLCAP00010057290 ENSLCAP00010058105 ENSLCAP00010058105 PPP6C-2 PPP6C-2 Prim2 Prim2 meiob meiob cenph cenph ENSLCAP00010008183 ENSLCAP00010008183 ENSLCAP00010009077 ENSLCAP00010009077 ENSLCAP00010009091 ENSLCAP00010009091 cenpp cenpp dscc1 dscc1 nop10 nop10 ENSLCAP00010010263 ENSLCAP00010010263 nhp2 nhp2 blm blm ENSLCAP00010011831 ENSLCAP00010011831 rpa3 rpa3 ENSLCAP00010012158 ENSLCAP00010012158 cdk2 cdk2 ENSLCAP00010053610 ENSLCAP00010053610 LOC108900385 LOC108900385 RPA1 RPA1 LOC108878404 LOC108878404
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
trub1Uncharacterized protein. (278 aa)
ENSLCAP00010051031Alpha thalassemia/mental retardation syndrome X-linked, like. (1695 aa)
LOC108873640-3Histone H4. (103 aa)
ENSLCAP00010050501annotation not available (67 aa)
ENSLCAP00010050488Zgc:110269. (339 aa)
LOC108877208Histone H2A; Belongs to the histone H2A family. (127 aa)
ENSLCAP00010050470Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (209 aa)
LOC108902035ANK_REP_REGION domain-containing protein. (168 aa)
rfc3AAA domain-containing protein. (356 aa)
LOC108886681Mis18 domain-containing protein. (178 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (632 aa)
dkc1PUA domain-containing protein. (507 aa)
ccna1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (416 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (193 aa)
Gar1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (222 aa)
ENSLCAP00010046546Ankyrin repeat domain 44. (1050 aa)
LOC108877697Histone domain-containing protein. (148 aa)
ENSLCAP00010045292Nucleophosmin 1a. (281 aa)
LOC108881908Daxx domain-containing protein. (723 aa)
chtf8Uncharacterized protein. (198 aa)
ENSLCAP00010044578Uncharacterized protein. (476 aa)
ENSLCAP00010044467BRCT domain-containing protein. (486 aa)
cdk2-2Cyclin-dependent kinase 2. (298 aa)
ten1Uncharacterized protein. (124 aa)
ENSLCAP00010042999Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (145 aa)
ENSLCAP00010042987Histone H2B; Belongs to the histone H2B family. (111 aa)
ENSLCAP00010042963Histone H2B; Belongs to the histone H2B family. (175 aa)
smarca5Uncharacterized protein. (1056 aa)
LOC108877712ANK_REP_REGION domain-containing protein. (1101 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (424 aa)
ENSLCAP00010041630Histone H2A; Belongs to the histone H2A family. (131 aa)
LOC108873639Histone H2B; Belongs to the histone H2B family. (122 aa)
LOC108900816Histone H2A; Belongs to the histone H2A family. (138 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
cenpwUncharacterized protein. (75 aa)
LOC108892908BTB domain-containing protein. (570 aa)
Ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (418 aa)
cenpiUncharacterized protein. (725 aa)
wrap53WD_REPEATS_REGION domain-containing protein. (557 aa)
Rfc5AAA domain-containing protein. (350 aa)
LOC108900468Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1108 aa)
ENSLCAP00010032564Alpha thalassemia/mental retardation syndrome X-linked homolog (human). (1999 aa)
ENSLCAP00010029557Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (118 aa)
ENSLCAP00010029552Uncharacterized protein; Belongs to the histone H2B family. (122 aa)
ENSLCAP00010029546Histone domain-containing protein; Belongs to the histone H2B family. (54 aa)
ENSLCAP00010029538CENP-T_C domain-containing protein. (82 aa)
ENSLCAP00010029533annotation not available (67 aa)
ENSLCAP00010029519Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (91 aa)
ENSLCAP00010029487Histone H2B; Belongs to the histone H2B family. (113 aa)
ENSLCAP00010029462Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
ENSLCAP00010029451Histone H2A; Belongs to the histone H2A family. (132 aa)
PPP6CSerine/threonine-protein phosphatase. (301 aa)
LOC108873640-2Histone H4. (103 aa)
ENSLCAP00010026604annotation not available (140 aa)
LOC108901759-2Histone H2B 1/2-like. (124 aa)
ENSLCAP00010026444Histone H2A; Belongs to the histone H2A family. (136 aa)
ENSLCAP00010026416annotation not available (67 aa)
ENSLCAP00010026411Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
LOC108901759Histone H2B; Belongs to the histone H2B family. (124 aa)
LOC108873640Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSLCAP00010026293Histone H2A; Belongs to the histone H2A family. (140 aa)
ankrd28ANK_REP_REGION domain-containing protein. (1083 aa)
rpa2RPA_C domain-containing protein. (290 aa)
LOC108893335Histone H2A; Belongs to the histone H2A family. (128 aa)
ENSLCAP00010022932Uncharacterized protein. (909 aa)
CenpqUncharacterized protein. (318 aa)
ENSLCAP00010021619Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
LOC108890174Histone H2B; Belongs to the histone H2B family. (143 aa)
exd23'-5' exonuclease domain-containing protein. (639 aa)
Rfc2Replication factor C (activator 1) 2. (444 aa)
ENSLCAP00010020841Remodeling and spacing factor 1b, tandem duplicate 1. (1709 aa)
ENSLCAP00010020695Retinoblastoma binding protein 4. (456 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
ENSLCAP00010019751Death-domain associated protein. (411 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (508 aa)
LOC108901361Histone H2A. (128 aa)
ENSLCAP00010018791Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (97 aa)
ENSLCAP00010018773Uncharacterized protein; Belongs to the histone H2A family. (244 aa)
ENSLCAP00010018730Uncharacterized protein; Belongs to the histone H2A family. (242 aa)
ENSLCAP00010018208Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (80 aa)
LOC108901366Histone H2B; Belongs to the histone H2B family. (124 aa)
ENSLCAP00010018196Histone H2A; Belongs to the histone H2A family. (138 aa)
ENSLCAP00010017650Retinoblastoma binding protein 4, like. (424 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (382 aa)
ENSLCAP00010000450TINF2_N domain-containing protein. (96 aa)
Pold1DNA polymerase. (1098 aa)
Pot1Protection of telomeres 1 homolog. (536 aa)
Rfc1Replication factor C subunit 1. (1148 aa)
ENSLCAP00010002355Histone H2A; Belongs to the histone H2A family. (134 aa)
ENSLCAP00010002534Nucleophosmin 1b. (314 aa)
LOC108875967Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
lig1DNA ligase. (1015 aa)
ENSLCAP00010006675Uncharacterized protein. (176 aa)
pold3Uncharacterized protein. (446 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
cenpnUncharacterized protein. (346 aa)
cenpkUncharacterized protein. (267 aa)
LOC108876221BTB domain-containing protein. (546 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1100 aa)
LOC108886744ANK_REP_REGION domain-containing protein. (168 aa)
pold2Uncharacterized protein. (471 aa)
LOC108892335Histone H2A; Belongs to the histone H2A family. (127 aa)
ENSLCAP00010054492Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (91 aa)
Terf2Uncharacterized protein. (185 aa)
ENSLCAP00010055044HTH myb-type domain-containing protein. (124 aa)
mis18aMis18 domain-containing protein. (223 aa)
pold4Uncharacterized protein. (108 aa)
cenpmUncharacterized protein. (184 aa)
ENSLCAP00010055640annotation not available (277 aa)
rfc4AAA domain-containing protein. (357 aa)
ENSLCAP00010055689SHQ1, H/ACA ribonucleoprotein assembly factor. (577 aa)
ENSLCAP00010055815Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (285 aa)
chtf18AAA domain-containing protein. (921 aa)
Dna2DNA replication helicase/nuclease 2. (1408 aa)
ccna2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (436 aa)
ENSLCAP00010057290Centromere protein X. (114 aa)
ENSLCAP00010058105Uncharacterized protein. (87 aa)
PPP6C-2Serine/threonine-protein phosphatase. (305 aa)
Prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (502 aa)
meiobUncharacterized protein. (460 aa)
cenphCENP-H domain-containing protein. (239 aa)
ENSLCAP00010008183RecQ helicase-like 4. (1236 aa)
ENSLCAP00010009077Histone H2A; Belongs to the histone H2A family. (108 aa)
ENSLCAP00010009091Histone H2B; Belongs to the histone H2B family. (67 aa)
cenppUncharacterized protein. (296 aa)
dscc1Uncharacterized protein. (390 aa)
nop10Uncharacterized protein. (64 aa)
ENSLCAP00010010263Histone H2B; Belongs to the histone H2B family. (117 aa)
nhp2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (159 aa)
blmUncharacterized protein. (1413 aa)
ENSLCAP00010011831DNA polymerase. (1466 aa)
rpa3Uncharacterized protein. (122 aa)
ENSLCAP00010012158Uncharacterized protein. (63 aa)
cdk2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
ENSLCAP00010053610Uncharacterized protein. (283 aa)
LOC108900385WD_REPEATS_REGION domain-containing protein. (434 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (678 aa)
LOC108878404Histone H2A; Belongs to the histone H2A family. (137 aa)
Your Current Organism:
Lates calcarifer
NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch
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