26 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bcl2	BH4_2 domain-containing protein. (229 aa)
	ccnd1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
	Pold1	DNA polymerase. (1098 aa)
	LOC108872926	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	mdm2	Uncharacterized protein. (511 aa)
	brca1	Uncharacterized protein. (1411 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	casp6	Uncharacterized protein; Belongs to the peptidase C14A family. (301 aa)
	ENSLCAP00010011831	DNA polymerase. (1466 aa)
	cdk2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	hus1	Checkpoint protein; Belongs to the HUS1 family. (285 aa)
	casp2	Uncharacterized protein; Belongs to the peptidase C14A family. (468 aa)
	casp9	Uncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
	CASP3	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. (259 aa)
	ccna2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (436 aa)
	ccna1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (416 aa)
	cdk2-2	Cyclin-dependent kinase 2. (298 aa)
	rad50	Zinc-hook domain-containing protein. (1313 aa)
	rad51c	RECA_2 domain-containing protein. (381 aa)
	ENSLCAP00010037861	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (279 aa)
	LOC108882983	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	LOC108877511	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	ENSLCAP00010032855	RAD17 checkpoint clamp loader component. (467 aa)
	Clic1	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (242 aa)
	ENSLCAP00010031718	DNA topoisomerase II binding protein 1. (1435 aa)
	Brca2	Breast cancer 2, early onset. (2872 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brca2	ENSLCAP00010011831	ENSLCAP00010030231	ENSLCAP00010011831	Breast cancer 2, early onset.	DNA polymerase.	0.623
Brca2	ENSLCAP00010031718	ENSLCAP00010030231	ENSLCAP00010031718	Breast cancer 2, early onset.	DNA topoisomerase II binding protein 1.	0.712
Brca2	ENSLCAP00010032855	ENSLCAP00010030231	ENSLCAP00010032855	Breast cancer 2, early onset.	RAD17 checkpoint clamp loader component.	0.738
Brca2	Pold1	ENSLCAP00010030231	ENSLCAP00010000489	Breast cancer 2, early onset.	DNA polymerase.	0.710
Brca2	brca1	ENSLCAP00010030231	ENSLCAP00010006276	Breast cancer 2, early onset.	Uncharacterized protein.	0.999
Brca2	ccna1	ENSLCAP00010030231	ENSLCAP00010047573	Breast cancer 2, early onset.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.411
Brca2	ccna2	ENSLCAP00010030231	ENSLCAP00010056469	Breast cancer 2, early onset.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.411
Brca2	cdk2	ENSLCAP00010030231	ENSLCAP00010014041	Breast cancer 2, early onset.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.480
Brca2	cdk2-2	ENSLCAP00010030231	ENSLCAP00010044385	Breast cancer 2, early onset.	Cyclin-dependent kinase 2.	0.480
Brca2	hus1	ENSLCAP00010030231	ENSLCAP00010016048	Breast cancer 2, early onset.	Checkpoint protein; Belongs to the HUS1 family.	0.655
Brca2	pcna	ENSLCAP00010030231	ENSLCAP00010007860	Breast cancer 2, early onset.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.520
Brca2	rad50	ENSLCAP00010030231	ENSLCAP00010043215	Breast cancer 2, early onset.	Zinc-hook domain-containing protein.	0.666
Brca2	rad51c	ENSLCAP00010030231	ENSLCAP00010038365	Breast cancer 2, early onset.	RECA_2 domain-containing protein.	0.997
CASP3	ENSLCAP00010037861	ENSLCAP00010058548	ENSLCAP00010037861	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.902
CASP3	LOC108872926	ENSLCAP00010058548	ENSLCAP00010004699	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.713
CASP3	LOC108877511	ENSLCAP00010058548	ENSLCAP00010035605	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.713
CASP3	LOC108882983	ENSLCAP00010058548	ENSLCAP00010035884	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.713
CASP3	bcl2	ENSLCAP00010058548	ENSLCAP00010023115	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	BH4_2 domain-containing protein.	0.546
CASP3	casp2	ENSLCAP00010058548	ENSLCAP00010021664	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.519
CASP3	casp9	ENSLCAP00010058548	ENSLCAP00010059818	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.973