10 items (Lates calcarifer) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	top2a	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1570 aa)
	CASP3	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. (259 aa)
	cdk4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (306 aa)
	cdk2-2	Cyclin-dependent kinase 2. (298 aa)
	ENSLCAP00010037861	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (279 aa)
	ccnd1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
	wee1	Wee1-like protein kinase. (620 aa)
	ENSLCAP00010013378	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (623 aa)
	cdk2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP3	ENSLCAP00010037861	ENSLCAP00010058548	ENSLCAP00010037861	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.902
ENSLCAP00010013378	ccnd1	ENSLCAP00010013378	ENSLCAP00010000381	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.579
ENSLCAP00010037861	CASP3	ENSLCAP00010037861	ENSLCAP00010058548	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.	0.902
akt1	top2a	ENSLCAP00010028358	ENSLCAP00010023475	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.543
ccnd1	ENSLCAP00010013378	ENSLCAP00010000381	ENSLCAP00010013378	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.579
ccnd1	cdk2	ENSLCAP00010000381	ENSLCAP00010014041	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.790
ccnd1	cdk2-2	ENSLCAP00010000381	ENSLCAP00010044385	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin-dependent kinase 2.	0.790
ccnd1	cdk4	ENSLCAP00010000381	ENSLCAP00010044799	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.989
cdk2	ccnd1	ENSLCAP00010014041	ENSLCAP00010000381	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.790
cdk2	top2a	ENSLCAP00010014041	ENSLCAP00010023475	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.649
cdk2	wee1	ENSLCAP00010014041	ENSLCAP00010005543	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Wee1-like protein kinase.	0.827
cdk2-2	ccnd1	ENSLCAP00010044385	ENSLCAP00010000381	Cyclin-dependent kinase 2.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.790
cdk2-2	top2a	ENSLCAP00010044385	ENSLCAP00010023475	Cyclin-dependent kinase 2.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.649
cdk2-2	wee1	ENSLCAP00010044385	ENSLCAP00010005543	Cyclin-dependent kinase 2.	Wee1-like protein kinase.	0.827
cdk4	ccnd1	ENSLCAP00010044799	ENSLCAP00010000381	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.989
cdk4	top2a	ENSLCAP00010044799	ENSLCAP00010023475	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.479
cdk4	wee1	ENSLCAP00010044799	ENSLCAP00010005543	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Wee1-like protein kinase.	0.753
top2a	akt1	ENSLCAP00010023475	ENSLCAP00010028358	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.543
top2a	cdk2	ENSLCAP00010023475	ENSLCAP00010014041	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.649
top2a	cdk2-2	ENSLCAP00010023475	ENSLCAP00010044385	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Cyclin-dependent kinase 2.	0.649