29 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	cdk2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	Rev1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1013 aa)
	fance	FA_FANCE domain-containing protein. (509 aa)
	ENSLCAP00010021231	FA complementation group F. (280 aa)
	ENSLCAP00010027048	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (314 aa)
	Cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (331 aa)
	Brca2	Breast cancer 2, early onset. (2872 aa)
	ENSLCAP00010034255	Exonuclease 1. (607 aa)
	Fanci	FA complementation group I. (1288 aa)
	atrip	Uncharacterized protein. (873 aa)
	Msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (908 aa)
	ENSLCAP00010043844	FA complementation group L. (375 aa)
	rad50	Zinc-hook domain-containing protein. (1313 aa)
	fancg	Uncharacterized protein. (627 aa)
	Dna2	DNA replication helicase/nuclease 2. (1408 aa)
	LOC108895090	Tyrosine-protein kinase. (543 aa)
	Fancd2	FA complementation group D2. (1422 aa)
	cdk4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (306 aa)
	fancm	Uncharacterized protein. (2146 aa)
	cdk2-2	Cyclin-dependent kinase 2. (298 aa)
	CDC37	Cell division cycle 37 homolog (S. cerevisiae). (377 aa)
	ENSLCAP00010002355	Histone H2A; Belongs to the histone H2A family. (134 aa)
	xrcc1	Uncharacterized protein. (627 aa)
	brca1	Uncharacterized protein. (1411 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	fancc	Uncharacterized protein. (589 aa)
	Mdc1	Uncharacterized protein. (2161 aa)
	Fancb	Uncharacterized protein. (319 aa)
	ENSLCAP00010013378	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (623 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brca2	Cdk1	ENSLCAP00010030231	ENSLCAP00010028139	Breast cancer 2, early onset.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.480
Brca2	Dna2	ENSLCAP00010030231	ENSLCAP00010056294	Breast cancer 2, early onset.	DNA replication helicase/nuclease 2.	0.902
Brca2	ENSLCAP00010021231	ENSLCAP00010030231	ENSLCAP00010021231	Breast cancer 2, early onset.	FA complementation group F.	0.654
Brca2	ENSLCAP00010027048	ENSLCAP00010030231	ENSLCAP00010027048	Breast cancer 2, early onset.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.999
Brca2	ENSLCAP00010034255	ENSLCAP00010030231	ENSLCAP00010034255	Breast cancer 2, early onset.	Exonuclease 1.	0.921
Brca2	ENSLCAP00010043844	ENSLCAP00010030231	ENSLCAP00010043844	Breast cancer 2, early onset.	FA complementation group L.	0.664
Brca2	Fancb	ENSLCAP00010030231	ENSLCAP00010012843	Breast cancer 2, early onset.	Uncharacterized protein.	0.617
Brca2	Fancd2	ENSLCAP00010030231	ENSLCAP00010046597	Breast cancer 2, early onset.	FA complementation group D2.	0.994
Brca2	Fanci	ENSLCAP00010030231	ENSLCAP00010036128	Breast cancer 2, early onset.	FA complementation group I.	0.769
Brca2	Mdc1	ENSLCAP00010030231	ENSLCAP00010009212	Breast cancer 2, early onset.	Uncharacterized protein.	0.627
Brca2	Msh2	ENSLCAP00010030231	ENSLCAP00010038465	Breast cancer 2, early onset.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.744
Brca2	Rev1	ENSLCAP00010030231	ENSLCAP00010014861	Breast cancer 2, early onset.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.557
Brca2	atrip	ENSLCAP00010030231	ENSLCAP00010037873	Breast cancer 2, early onset.	Uncharacterized protein.	0.613
Brca2	brca1	ENSLCAP00010030231	ENSLCAP00010006276	Breast cancer 2, early onset.	Uncharacterized protein.	0.999
Brca2	cdk2	ENSLCAP00010030231	ENSLCAP00010014041	Breast cancer 2, early onset.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.480
Brca2	cdk2-2	ENSLCAP00010030231	ENSLCAP00010044385	Breast cancer 2, early onset.	Cyclin-dependent kinase 2.	0.480
Brca2	cdk4	ENSLCAP00010030231	ENSLCAP00010044799	Breast cancer 2, early onset.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.480
Brca2	fancc	ENSLCAP00010030231	ENSLCAP00010008646	Breast cancer 2, early onset.	Uncharacterized protein.	0.653
Brca2	fancg	ENSLCAP00010030231	ENSLCAP00010060539	Breast cancer 2, early onset.	Uncharacterized protein.	0.846
Brca2	fancm	ENSLCAP00010030231	ENSLCAP00010044771	Breast cancer 2, early onset.	Uncharacterized protein.	0.840