18 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAMAC	Uncharacterized protein. (191 aa)
	kpnb1	Importin N-terminal domain-containing protein. (932 aa)
	cdk5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (292 aa)
	e2f1	E2F_TDP domain-containing protein. (454 aa)
	cdk2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	ccne1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (433 aa)
	SPX	Spexin hormone. (120 aa)
	LOC108900731	F-box domain-containing protein. (421 aa)
	Cdk9	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (374 aa)
	Cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (331 aa)
	bop1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (759 aa)
	tomm70	TPR_REGION domain-containing protein. (578 aa)
	Ddx18	RNA helicase. (697 aa)
	rngtt	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (602 aa)
	ENSLCAP00010042296	Spexin hormone. (120 aa)
	cdk2-2	Cyclin-dependent kinase 2. (298 aa)
	ccnb1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (404 aa)
	cdk7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (343 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdk1	LOC108900731	ENSLCAP00010028139	ENSLCAP00010024210	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	F-box domain-containing protein.	0.784
Cdk1	ccnb1	ENSLCAP00010028139	ENSLCAP00010049414	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.996
Cdk1	ccne1	ENSLCAP00010028139	ENSLCAP00010020590	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.815
Cdk1	cdk5	ENSLCAP00010028139	ENSLCAP00010010142	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.419
Cdk1	cdk7	ENSLCAP00010028139	ENSLCAP00010060477	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.955
Cdk1	e2f1	ENSLCAP00010028139	ENSLCAP00010013681	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	E2F_TDP domain-containing protein.	0.661
Cdk9	ENSLCAP00010042296	ENSLCAP00010025072	ENSLCAP00010042296	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	Spexin hormone.	0.480
Cdk9	SPX	ENSLCAP00010025072	ENSLCAP00010023068	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	Spexin hormone.	0.480
Cdk9	cdk7	ENSLCAP00010025072	ENSLCAP00010060477	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.792
Ddx18	LOC108900731	ENSLCAP00010032471	ENSLCAP00010024210	RNA helicase.	F-box domain-containing protein.	0.551
Ddx18	RAMAC	ENSLCAP00010032471	ENSLCAP00010010421	RNA helicase.	Uncharacterized protein.	0.400
Ddx18	bop1	ENSLCAP00010032471	ENSLCAP00010030010	RNA helicase.	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.994
Ddx18	kpnb1	ENSLCAP00010032471	ENSLCAP00010007394	RNA helicase.	Importin N-terminal domain-containing protein.	0.440
Ddx18	rngtt	ENSLCAP00010032471	ENSLCAP00010037881	RNA helicase.	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.	0.468
Ddx18	tomm70	ENSLCAP00010032471	ENSLCAP00010030943	RNA helicase.	TPR_REGION domain-containing protein.	0.554
ENSLCAP00010042296	Cdk9	ENSLCAP00010042296	ENSLCAP00010025072	Spexin hormone.	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	0.480
ENSLCAP00010042296	cdk5	ENSLCAP00010042296	ENSLCAP00010010142	Spexin hormone.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.476
ENSLCAP00010042296	cdk7	ENSLCAP00010042296	ENSLCAP00010060477	Spexin hormone.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.407
LOC108900731	Cdk1	ENSLCAP00010024210	ENSLCAP00010028139	F-box domain-containing protein.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.784
LOC108900731	Ddx18	ENSLCAP00010024210	ENSLCAP00010032471	F-box domain-containing protein.	RNA helicase.	0.551