18 items (Lates calcarifer) - STRING interaction network

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	ube2i	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (173 aa)
	lig1	DNA ligase. (1015 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	Rad1	RAD1 homolog (S. pombe). (329 aa)
	cdk2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	prmt5	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (658 aa)
	hus1	Checkpoint protein; Belongs to the HUS1 family. (285 aa)
	sae1	ThiF domain-containing protein. (348 aa)
	fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
	YY1	Uncharacterized protein. (474 aa)
	Cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (331 aa)
	sumo2	Small ubiquitin-related modifier. (110 aa)
	ENSLCAP00010037276	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (634 aa)
	sumo1	Small ubiquitin-related modifier. (101 aa)
	cdk2-2	Cyclin-dependent kinase 2. (298 aa)
	ccna1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (416 aa)
	ccna2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (436 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdk1	ccna1	ENSLCAP00010028139	ENSLCAP00010047573	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.995
Cdk1	ccna2	ENSLCAP00010028139	ENSLCAP00010056469	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.992
Cdk1	lig1	ENSLCAP00010028139	ENSLCAP00010005263	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	DNA ligase.	0.430
Cdk1	pcna	ENSLCAP00010028139	ENSLCAP00010007860	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.606
Cdk1	prmt5	ENSLCAP00010028139	ENSLCAP00010015555	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.665
ENSLCAP00010037276	Rad1	ENSLCAP00010037276	ENSLCAP00010011028	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	RAD1 homolog (S. pombe).	0.400
ENSLCAP00010037276	fen1	ENSLCAP00010037276	ENSLCAP00010020106	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.432
ENSLCAP00010037276	lig1	ENSLCAP00010037276	ENSLCAP00010005263	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	DNA ligase.	0.402
ENSLCAP00010037276	sae1	ENSLCAP00010037276	ENSLCAP00010019884	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	ThiF domain-containing protein.	0.999
ENSLCAP00010037276	sumo1	ENSLCAP00010037276	ENSLCAP00010041422	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Small ubiquitin-related modifier.	0.996
ENSLCAP00010037276	sumo2	ENSLCAP00010037276	ENSLCAP00010029594	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Small ubiquitin-related modifier.	0.957
ENSLCAP00010037276	ube2i	ENSLCAP00010037276	ENSLCAP00010056757	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.986
Rad1	ENSLCAP00010037276	ENSLCAP00010011028	ENSLCAP00010037276	RAD1 homolog (S. pombe).	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.400
Rad1	fen1	ENSLCAP00010011028	ENSLCAP00010020106	RAD1 homolog (S. pombe).	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.921
Rad1	hus1	ENSLCAP00010011028	ENSLCAP00010016048	RAD1 homolog (S. pombe).	Checkpoint protein; Belongs to the HUS1 family.	0.999
Rad1	lig1	ENSLCAP00010011028	ENSLCAP00010005263	RAD1 homolog (S. pombe).	DNA ligase.	0.517
Rad1	sae1	ENSLCAP00010011028	ENSLCAP00010019884	RAD1 homolog (S. pombe).	ThiF domain-containing protein.	0.400
Rad1	sumo1	ENSLCAP00010011028	ENSLCAP00010041422	RAD1 homolog (S. pombe).	Small ubiquitin-related modifier.	0.480
YY1	sumo1	ENSLCAP00010026739	ENSLCAP00010041422	Uncharacterized protein.	Small ubiquitin-related modifier.	0.481
ccna1	Cdk1	ENSLCAP00010047573	ENSLCAP00010028139	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.995