46 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLCAP00010009852	Lectin, mannose-binding, 1. (514 aa)
	hadh	Uncharacterized protein. (309 aa)
	mcm4	DNA helicase; Belongs to the MCM family. (860 aa)
	mcm3	DNA helicase; Belongs to the MCM family. (815 aa)
	foxo3	Fork-head domain-containing protein. (668 aa)
	cdk2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	arhgef2	Uncharacterized protein. (970 aa)
	hspa5	Uncharacterized protein; Belongs to the heat shock protein 70 family. (659 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (345 aa)
	LOC108890964	Uncharacterized protein. (494 aa)
	LOC108882499	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (573 aa)
	ENSLCAP00010023490	Ubiquitin-conjugating enzyme E2A (RAD6 homolog). (147 aa)
	ENSLCAP00010023679	Ring finger protein 25. (264 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
	ENSLCAP00010024568	Integrin alpha 4; Belongs to the integrin alpha chain family. (975 aa)
	Psmb7	Proteasome subunit beta. (305 aa)
	LOC108902665	Uncharacterized protein. (228 aa)
	LOC108875315	Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family. (792 aa)
	Cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (331 aa)
	LOC108886921	PNPLA domain-containing protein. (513 aa)
	usp28	USP domain-containing protein; Belongs to the peptidase C19 family. (1204 aa)
	usp25	USP domain-containing protein; Belongs to the peptidase C19 family. (1168 aa)
	Erlec1	Endoplasmic reticulum lectin 1. (494 aa)
	LOC108873472	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (332 aa)
	lpin1	LNS2 domain-containing protein. (923 aa)
	cpt1a	Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family. (791 aa)
	ENSLCAP00010040528	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (161 aa)
	Col1a2	Collagen, type I, alpha 2. (1220 aa)
	cdk2-2	Cyclin-dependent kinase 2. (298 aa)
	ccnb1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (404 aa)
	Pold1	DNA polymerase. (1098 aa)
	UBE2A	Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	pdhb	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
	fyn	Tyrosine-protein kinase. (538 aa)
	wee1	Wee1-like protein kinase. (620 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	LOC108890068	Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. (640 aa)
	mcm6	DNA helicase; Belongs to the MCM family. (832 aa)
	Lamc1	Laminin, gamma 1. (1598 aa)
	Slc27a1	Solute carrier family 27 (fatty acid transporter), member 1a. (651 aa)
	rpl22l1	Uncharacterized protein. (151 aa)
	ENSLCAP00010055075	Lipin 1. (776 aa)
	pdia3	Protein disulfide-isomerase. (511 aa)
	usp19	Uncharacterized protein. (1574 aa)
	ccna2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (436 aa)
	gsk3b	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (425 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdk1	ENSLCAP00010023679	ENSLCAP00010028139	ENSLCAP00010023679	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Ring finger protein 25.	0.472
Cdk1	ENSLCAP00010055075	ENSLCAP00010028139	ENSLCAP00010055075	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Lipin 1.	0.437
Cdk1	LOC108882499	ENSLCAP00010028139	ENSLCAP00010059323	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.831
Cdk1	LOC108890068	ENSLCAP00010028139	ENSLCAP00010008325	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.	0.406
Cdk1	Lamc1	ENSLCAP00010028139	ENSLCAP00010008996	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Laminin, gamma 1.	0.447
Cdk1	Pold1	ENSLCAP00010028139	ENSLCAP00010000489	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	DNA polymerase.	0.663
Cdk1	arhgef2	ENSLCAP00010028139	ENSLCAP00010016389	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.477
Cdk1	ccna2	ENSLCAP00010028139	ENSLCAP00010056469	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.992
Cdk1	ccnb1	ENSLCAP00010028139	ENSLCAP00010049414	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.996
Cdk1	lpin1	ENSLCAP00010028139	ENSLCAP00010038206	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	LNS2 domain-containing protein.	0.437
Cdk1	mcm3	ENSLCAP00010028139	ENSLCAP00010011628	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	DNA helicase; Belongs to the MCM family.	0.722
Cdk1	mcm4	ENSLCAP00010028139	ENSLCAP00010011193	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	DNA helicase; Belongs to the MCM family.	0.720
Cdk1	mcm6	ENSLCAP00010028139	ENSLCAP00010008674	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	DNA helicase; Belongs to the MCM family.	0.707
Cdk1	pcna	ENSLCAP00010028139	ENSLCAP00010007860	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.606
Cdk1	pdia3	ENSLCAP00010028139	ENSLCAP00010055239	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Protein disulfide-isomerase.	0.466
Cdk1	wee1	ENSLCAP00010028139	ENSLCAP00010005543	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Wee1-like protein kinase.	0.974
Col1a2	LOC108902665	ENSLCAP00010040588	ENSLCAP00010026142	Collagen, type I, alpha 2.	Uncharacterized protein.	0.496
Col1a2	pdhb	ENSLCAP00010040588	ENSLCAP00010001295	Collagen, type I, alpha 2.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.523
Col1a2	rpl22l1	ENSLCAP00010040588	ENSLCAP00010054508	Collagen, type I, alpha 2.	Uncharacterized protein.	0.521
ENSLCAP00010009852	Erlec1	ENSLCAP00010009852	ENSLCAP00010033691	Lectin, mannose-binding, 1.	Endoplasmic reticulum lectin 1.	0.508