42 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLCAP00010032855	RAD17 checkpoint clamp loader component. (467 aa)
	ENSLCAP00010031718	DNA topoisomerase II binding protein 1. (1435 aa)
	rad52	Uncharacterized protein. (435 aa)
	ENSLCAP00010030587	Helicase-like transcription factor. (813 aa)
	Brca2	Breast cancer 2, early onset. (2872 aa)
	Cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (331 aa)
	Slx4	Uncharacterized protein. (262 aa)
	hus1	Checkpoint protein; Belongs to the HUS1 family. (285 aa)
	cdk2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	mus81	ERCC4 domain-containing protein. (622 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	primpol	Uncharacterized protein. (533 aa)
	cdc45	Uncharacterized protein. (568 aa)
	brca1	Uncharacterized protein. (1411 aa)
	Rmi2	RecQ mediated genome instability 2. (91 aa)
	wee1	Wee1-like protein kinase. (620 aa)
	foxm1	Fork-head domain-containing protein. (678 aa)
	dbf4	Uncharacterized protein. (628 aa)
	recql5	Uncharacterized protein. (1020 aa)
	Pold1	DNA polymerase. (1098 aa)
	EME2	ERCC4 domain-containing protein. (443 aa)
	rmi1	DUF1767 domain-containing protein. (700 aa)
	LOC108882499	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (573 aa)
	ccna2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (436 aa)
	Dna2	DNA replication helicase/nuclease 2. (1408 aa)
	eme1	ERCC4 domain-containing protein. (571 aa)
	ENSLCAP00010051068	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (764 aa)
	ccnb1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (404 aa)
	PLK1	Serine/threonine-protein kinase PLK. (569 aa)
	cdc7	Protein kinase domain-containing protein. (610 aa)
	zranb3	Uncharacterized protein. (1161 aa)
	pif1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (632 aa)
	ccna1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (416 aa)
	LOC108895202	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (271 aa)
	Fancd2	FA complementation group D2. (1422 aa)
	fancm	Uncharacterized protein. (2146 aa)
	cdk2-2	Cyclin-dependent kinase 2. (298 aa)
	ercc1	Uncharacterized protein. (360 aa)
	traip	RING-type domain-containing protein. (447 aa)
	atrip	Uncharacterized protein. (873 aa)
	hras	Uncharacterized protein. (189 aa)
	Fanci	FA complementation group I. (1288 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brca2	Cdk1	ENSLCAP00010030231	ENSLCAP00010028139	Breast cancer 2, early onset.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.480
Brca2	Dna2	ENSLCAP00010030231	ENSLCAP00010056294	Breast cancer 2, early onset.	DNA replication helicase/nuclease 2.	0.902
Brca2	EME2	ENSLCAP00010030231	ENSLCAP00010000382	Breast cancer 2, early onset.	ERCC4 domain-containing protein.	0.401
Brca2	ENSLCAP00010030587	ENSLCAP00010030231	ENSLCAP00010030587	Breast cancer 2, early onset.	Helicase-like transcription factor.	0.620
Brca2	ENSLCAP00010031718	ENSLCAP00010030231	ENSLCAP00010031718	Breast cancer 2, early onset.	DNA topoisomerase II binding protein 1.	0.712
Brca2	ENSLCAP00010032855	ENSLCAP00010030231	ENSLCAP00010032855	Breast cancer 2, early onset.	RAD17 checkpoint clamp loader component.	0.738
Brca2	ENSLCAP00010051068	ENSLCAP00010030231	ENSLCAP00010051068	Breast cancer 2, early onset.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.	0.745
Brca2	Fancd2	ENSLCAP00010030231	ENSLCAP00010046597	Breast cancer 2, early onset.	FA complementation group D2.	0.994
Brca2	Fanci	ENSLCAP00010030231	ENSLCAP00010036128	Breast cancer 2, early onset.	FA complementation group I.	0.769
Brca2	LOC108895202	ENSLCAP00010030231	ENSLCAP00010047447	Breast cancer 2, early onset.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.654
Brca2	PLK1	ENSLCAP00010030231	ENSLCAP00010049256	Breast cancer 2, early onset.	Serine/threonine-protein kinase PLK.	0.677
Brca2	Pold1	ENSLCAP00010030231	ENSLCAP00010000489	Breast cancer 2, early onset.	DNA polymerase.	0.710
Brca2	Rmi2	ENSLCAP00010030231	ENSLCAP00010005819	Breast cancer 2, early onset.	RecQ mediated genome instability 2.	0.685
Brca2	Slx4	ENSLCAP00010030231	ENSLCAP00010023861	Breast cancer 2, early onset.	Uncharacterized protein.	0.796
Brca2	atrip	ENSLCAP00010030231	ENSLCAP00010037873	Breast cancer 2, early onset.	Uncharacterized protein.	0.613
Brca2	brca1	ENSLCAP00010030231	ENSLCAP00010006276	Breast cancer 2, early onset.	Uncharacterized protein.	0.999
Brca2	ccna1	ENSLCAP00010030231	ENSLCAP00010047573	Breast cancer 2, early onset.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.411
Brca2	ccna2	ENSLCAP00010030231	ENSLCAP00010056469	Breast cancer 2, early onset.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.411
Brca2	cdc45	ENSLCAP00010030231	ENSLCAP00010007031	Breast cancer 2, early onset.	Uncharacterized protein.	0.542
Brca2	cdk2	ENSLCAP00010030231	ENSLCAP00010014041	Breast cancer 2, early onset.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.480