36 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rad52	Uncharacterized protein. (435 aa)
	rmi1	DUF1767 domain-containing protein. (700 aa)
	Sart3	Uncharacterized protein. (895 aa)
	rnf11	RING-type domain-containing protein. (154 aa)
	LOC108872827	Uncharacterized protein. (970 aa)
	LOC108872813	Uncharacterized protein. (961 aa)
	rad18	Uncharacterized protein. (505 aa)
	Dna2	DNA replication helicase/nuclease 2. (1408 aa)
	ENSLCAP00010053132	Ubiquitin carboxyl-terminal hydrolase. (763 aa)
	ENSLCAP00010051068	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (764 aa)
	zranb3	Uncharacterized protein. (1161 aa)
	Fancd2	FA complementation group D2. (1422 aa)
	timeless	Uncharacterized protein. (1251 aa)
	cdk2-2	Cyclin-dependent kinase 2. (298 aa)
	Shprh	SNF2 histone linker PHD RING helicase. (1632 aa)
	rnf8	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (523 aa)
	atrip	Uncharacterized protein. (873 aa)
	Fanci	FA complementation group I. (1288 aa)
	ENSLCAP00010034255	Exonuclease 1. (607 aa)
	ENSLCAP00010030587	Helicase-like transcription factor. (813 aa)
	Brca2	Breast cancer 2, early onset. (2872 aa)
	LOC108873154	Uncharacterized protein. (1047 aa)
	LOC108873124	Uncharacterized protein. (888 aa)
	braf	Uncharacterized protein. (856 aa)
	LOC108886534	Uncharacterized protein. (663 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	Wrnip1	Werner helicase interacting protein 1. (614 aa)
	LOC108895487	Uncharacterized protein. (945 aa)
	Pum1	Pumilio RNA-binding family member 1. (555 aa)
	cdk2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	primpol	Uncharacterized protein. (533 aa)
	brca1	Uncharacterized protein. (1411 aa)
	wee1	Wee1-like protein kinase. (620 aa)
	mdm2	Uncharacterized protein. (511 aa)
	Parp10	Si:ch1073-296d18.1. (1017 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brca2	Dna2	ENSLCAP00010030231	ENSLCAP00010056294	Breast cancer 2, early onset.	DNA replication helicase/nuclease 2.	0.902
Brca2	ENSLCAP00010030587	ENSLCAP00010030231	ENSLCAP00010030587	Breast cancer 2, early onset.	Helicase-like transcription factor.	0.620
Brca2	ENSLCAP00010034255	ENSLCAP00010030231	ENSLCAP00010034255	Breast cancer 2, early onset.	Exonuclease 1.	0.921
Brca2	ENSLCAP00010051068	ENSLCAP00010030231	ENSLCAP00010051068	Breast cancer 2, early onset.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.	0.745
Brca2	ENSLCAP00010053132	ENSLCAP00010030231	ENSLCAP00010053132	Breast cancer 2, early onset.	Ubiquitin carboxyl-terminal hydrolase.	0.420
Brca2	Fancd2	ENSLCAP00010030231	ENSLCAP00010046597	Breast cancer 2, early onset.	FA complementation group D2.	0.994
Brca2	Fanci	ENSLCAP00010030231	ENSLCAP00010036128	Breast cancer 2, early onset.	FA complementation group I.	0.769
Brca2	Shprh	ENSLCAP00010030231	ENSLCAP00010042394	Breast cancer 2, early onset.	SNF2 histone linker PHD RING helicase.	0.423
Brca2	Wrnip1	ENSLCAP00010030231	ENSLCAP00010020271	Breast cancer 2, early onset.	Werner helicase interacting protein 1.	0.486
Brca2	atrip	ENSLCAP00010030231	ENSLCAP00010037873	Breast cancer 2, early onset.	Uncharacterized protein.	0.613
Brca2	brca1	ENSLCAP00010030231	ENSLCAP00010006276	Breast cancer 2, early onset.	Uncharacterized protein.	0.999
Brca2	cdk2	ENSLCAP00010030231	ENSLCAP00010014041	Breast cancer 2, early onset.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.480
Brca2	cdk2-2	ENSLCAP00010030231	ENSLCAP00010044385	Breast cancer 2, early onset.	Cyclin-dependent kinase 2.	0.480
Brca2	parp1	ENSLCAP00010030231	ENSLCAP00010021233	Breast cancer 2, early onset.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.887
Brca2	pcna	ENSLCAP00010030231	ENSLCAP00010007860	Breast cancer 2, early onset.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.520
Brca2	primpol	ENSLCAP00010030231	ENSLCAP00010007106	Breast cancer 2, early onset.	Uncharacterized protein.	0.562
Brca2	rad18	ENSLCAP00010030231	ENSLCAP00010056799	Breast cancer 2, early onset.	Uncharacterized protein.	0.458
Brca2	rad52	ENSLCAP00010030231	ENSLCAP00010030790	Breast cancer 2, early onset.	Uncharacterized protein.	0.786
Brca2	rmi1	ENSLCAP00010030231	ENSLCAP00010060933	Breast cancer 2, early onset.	DUF1767 domain-containing protein.	0.724
Brca2	zranb3	ENSLCAP00010030231	ENSLCAP00010048726	Breast cancer 2, early onset.	Uncharacterized protein.	0.678