STRINGSTRING
ppm1d ppm1d ENSLCAP00010051639 ENSLCAP00010051639 tet2 tet2 LOC108879980 LOC108879980 mdm4 mdm4 Has2 Has2 Msh6 Msh6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppm1dPPM-type phosphatase domain-containing protein. (598 aa)
ENSLCAP00010051639Uncharacterized protein. (521 aa)
tet2Tet_JBP domain-containing protein. (1853 aa)
LOC108879980Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (380 aa)
mdm4RanBP2-type domain-containing protein; Belongs to the MDM2/MDM4 family. (496 aa)
Has2Hyaluronan synthase 2. (554 aa)
Msh6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1241 aa)
Your Current Organism:
Lates calcarifer
NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch
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