16 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	wee1	Wee1-like protein kinase. (620 aa)
	RRM2-2	Uncharacterized protein. (412 aa)
	LOC108894047	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa)
	cdc7	Protein kinase domain-containing protein. (610 aa)
	dck	dNK domain-containing protein. (271 aa)
	cdk2-2	Cyclin-dependent kinase 2. (298 aa)
	ercc1	Uncharacterized protein. (360 aa)
	RRM2	Uncharacterized protein. (355 aa)
	Cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (331 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
	cdk2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	arid1a	ARID domain-containing protein. (2320 aa)
	dut	dUTPase domain-containing protein. (166 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	xrcc1	Uncharacterized protein. (627 aa)
	mcm4	DNA helicase; Belongs to the MCM family. (860 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdk1	cdc7	ENSLCAP00010028139	ENSLCAP00010048952	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.705
Cdk1	mcm4	ENSLCAP00010028139	ENSLCAP00010011193	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	DNA helicase; Belongs to the MCM family.	0.720
Cdk1	pcna	ENSLCAP00010028139	ENSLCAP00010007860	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.606
Cdk1	wee1	ENSLCAP00010028139	ENSLCAP00010005543	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Wee1-like protein kinase.	0.974
LOC108894047	RRM2	ENSLCAP00010055091	ENSLCAP00010039074	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Uncharacterized protein.	0.948
LOC108894047	RRM2-2	ENSLCAP00010055091	ENSLCAP00010056027	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Uncharacterized protein.	0.994
LOC108894047	dck	ENSLCAP00010055091	ENSLCAP00010046529	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	dNK domain-containing protein.	0.538
LOC108894047	dut	ENSLCAP00010055091	ENSLCAP00010006923	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	dUTPase domain-containing protein.	0.778
LOC108894047	mcm4	ENSLCAP00010055091	ENSLCAP00010011193	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	DNA helicase; Belongs to the MCM family.	0.897
LOC108894047	pcna	ENSLCAP00010055091	ENSLCAP00010007860	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.890
RRM2	LOC108894047	ENSLCAP00010039074	ENSLCAP00010055091	Uncharacterized protein.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.948
RRM2	cdk2	ENSLCAP00010039074	ENSLCAP00010014041	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.410
RRM2	cdk2-2	ENSLCAP00010039074	ENSLCAP00010044385	Uncharacterized protein.	Cyclin-dependent kinase 2.	0.410
RRM2	dut	ENSLCAP00010039074	ENSLCAP00010006923	Uncharacterized protein.	dUTPase domain-containing protein.	0.498
RRM2	mcm4	ENSLCAP00010039074	ENSLCAP00010011193	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.684
RRM2	pcna	ENSLCAP00010039074	ENSLCAP00010007860	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.680
RRM2-2	LOC108894047	ENSLCAP00010056027	ENSLCAP00010055091	Uncharacterized protein.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.994
RRM2-2	dut	ENSLCAP00010056027	ENSLCAP00010006923	Uncharacterized protein.	dUTPase domain-containing protein.	0.498
RRM2-2	mcm4	ENSLCAP00010056027	ENSLCAP00010011193	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.684
RRM2-2	pcna	ENSLCAP00010056027	ENSLCAP00010007860	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.680