26 items (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108874357	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (463 aa)
	Htt	Huntingtin. (3100 aa)
	sumo1	Small ubiquitin-related modifier. (101 aa)
	ENSLCAP00010039872	SprT-like N-terminal domain. (520 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (609 aa)
	mcu	MCU domain-containing protein. (377 aa)
	ENSLCAP00010031904	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (459 aa)
	atxn1	AXH domain-containing protein. (826 aa)
	ENSLCAP00010027829	Polynucleotide kinase 3'-phosphatase. (578 aa)
	tecr	S5A_REDUCTASE domain-containing protein. (349 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (486 aa)
	LOC108890957	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (473 aa)
	bag3	Uncharacterized protein. (572 aa)
	ACLY	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1115 aa)
	tmco1	Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling. (188 aa)
	hsdl2	SCP2 domain-containing protein. (425 aa)
	ENSLCAP00010014502	Calnexin. (620 aa)
	slc27a4	Uncharacterized protein. (648 aa)
	casp7	Uncharacterized protein; Belongs to the peptidase C14A family. (316 aa)
	LOC108882770	Uncharacterized protein. (691 aa)
	ENSLCAP00010001502	ATP citrate lyase. (1069 aa)
	vcp	Uncharacterized protein. (872 aa)
	ewsr1	Uncharacterized protein. (603 aa)
	CASP3	Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. (259 aa)
	Hdac3	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (459 aa)
	LOC108893617	Uncharacterized protein. (765 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLCAP00010014502	ENSLCAP00010039872	ENSLCAP00010014502	ENSLCAP00010039872	Calnexin.	SprT-like N-terminal domain.	0.406
ENSLCAP00010014502	bag3	ENSLCAP00010014502	ENSLCAP00010016209	Calnexin.	Uncharacterized protein.	0.484
ENSLCAP00010014502	vcp	ENSLCAP00010014502	ENSLCAP00010060533	Calnexin.	Uncharacterized protein.	0.475
ENSLCAP00010027829	Htt	ENSLCAP00010027829	ENSLCAP00010045630	Polynucleotide kinase 3'-phosphatase.	Huntingtin.	0.445
ENSLCAP00010031904	Htt	ENSLCAP00010031904	ENSLCAP00010045630	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Huntingtin.	0.598
ENSLCAP00010031904	sumo1	ENSLCAP00010031904	ENSLCAP00010041422	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Small ubiquitin-related modifier.	0.456
ENSLCAP00010031904	vcp	ENSLCAP00010031904	ENSLCAP00010060533	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Uncharacterized protein.	0.463
ENSLCAP00010039872	ENSLCAP00010014502	ENSLCAP00010039872	ENSLCAP00010014502	SprT-like N-terminal domain.	Calnexin.	0.406
ENSLCAP00010039872	sumo1	ENSLCAP00010039872	ENSLCAP00010041422	SprT-like N-terminal domain.	Small ubiquitin-related modifier.	0.487
ENSLCAP00010039872	vcp	ENSLCAP00010039872	ENSLCAP00010060533	SprT-like N-terminal domain.	Uncharacterized protein.	0.858
Hdac3	sumo1	ENSLCAP00010054703	ENSLCAP00010041422	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Small ubiquitin-related modifier.	0.461
Htt	ENSLCAP00010027829	ENSLCAP00010045630	ENSLCAP00010027829	Huntingtin.	Polynucleotide kinase 3'-phosphatase.	0.445
Htt	ENSLCAP00010031904	ENSLCAP00010045630	ENSLCAP00010031904	Huntingtin.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.598
Htt	LOC108874357	ENSLCAP00010045630	ENSLCAP00010048920	Huntingtin.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.598
Htt	LOC108882770	ENSLCAP00010045630	ENSLCAP00010008657	Huntingtin.	Uncharacterized protein.	0.485
Htt	LOC108893617	ENSLCAP00010045630	ENSLCAP00010050141	Huntingtin.	Uncharacterized protein.	0.485
Htt	vcp	ENSLCAP00010045630	ENSLCAP00010060533	Huntingtin.	Uncharacterized protein.	0.673
LOC108874357	Htt	ENSLCAP00010048920	ENSLCAP00010045630	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Huntingtin.	0.598
LOC108874357	sumo1	ENSLCAP00010048920	ENSLCAP00010041422	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Small ubiquitin-related modifier.	0.456
LOC108874357	vcp	ENSLCAP00010048920	ENSLCAP00010060533	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Uncharacterized protein.	0.463