(34 nodes) Guanine nucleotide exchange factor for Ras-like small GTPases network (Lates calcarifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rasgrp3	RAS guanyl releasing protein 3 (calcium and DAG-regulated). (692 aa)
	rapgef4	Uncharacterized protein. (1025 aa)
	rgl1	Uncharacterized protein. (809 aa)
	LOC108877024	Uncharacterized protein. (1257 aa)
	LOC108886373	Uncharacterized protein. (868 aa)
	Sos2	Son of sevenless homolog 2 (Drosophila). (1308 aa)
	Rapgefl1	Rap guanine nucleotide exchange factor (GEF)-like 1. (381 aa)
	ENSLCAP00010049166	Rap guanine nucleotide exchange factor (GEF) 2. (1603 aa)
	ENSLCAP00010049147	Uncharacterized protein. (550 aa)
	LOC108898698	Uncharacterized protein. (752 aa)
	ENSLCAP00010046243	BCAR3, NSP family adaptor protein. (680 aa)
	LOC108883636	Uncharacterized protein. (996 aa)
	RASGRP1	RAS guanyl releasing protein 1. (773 aa)
	RASGEF1B	Uncharacterized protein. (538 aa)
	ENSLCAP00010000305	Ral guanine nucleotide dissociation stimulator-like 3a. (461 aa)
	LOC108886034	Uncharacterized protein. (598 aa)
	LOC108899459	Uncharacterized protein. (742 aa)
	rapgef1	Uncharacterized protein. (1100 aa)
	LOC108879284	Uncharacterized protein. (892 aa)
	Rasgrf2	Ras protein specific guanine nucleotide releasing factor 2. (1247 aa)
	RASGEF1C	RasGEF domain family member 1C. (490 aa)
	LOC108875322	Uncharacterized protein. (1256 aa)
	ENSLCAP00010012600	RAS guanyl releasing protein 4. (504 aa)
	LOC108901984	Uncharacterized protein. (536 aa)
	ralgds	Uncharacterized protein. (857 aa)
	ENSLCAP00010015053	SH2 domain containing 3Cb. (584 aa)
	ralgps2	Uncharacterized protein. (586 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (643 aa)
	RASGRP2	Uncharacterized protein. (598 aa)
	ENSLCAP00010025047	Ras protein-specific guanine nucleotide-releasing factor 2a. (1166 aa)
	Sos1	Son of sevenless homolog 1 (Drosophila). (1316 aa)
	ENSLCAP00010026528	Ras-GEF domain-containing protein. (448 aa)
	Ralgps1	Ras-GEF domain-containing protein. (285 aa)
	rapgef6	Uncharacterized protein. (1716 aa)

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLCAP00010025047	ENSLCAP00010049166	ENSLCAP00010025047	ENSLCAP00010049166	Ras protein-specific guanine nucleotide-releasing factor 2a.	Rap guanine nucleotide exchange factor (GEF) 2.	0.402
ENSLCAP00010025047	LOC108875322	ENSLCAP00010025047	ENSLCAP00010012066	Ras protein-specific guanine nucleotide-releasing factor 2a.	Uncharacterized protein.	0.474
ENSLCAP00010025047	LOC108877024	ENSLCAP00010025047	ENSLCAP00010052471	Ras protein-specific guanine nucleotide-releasing factor 2a.	Uncharacterized protein.	0.474
ENSLCAP00010026528	Rapgefl1	ENSLCAP00010026528	ENSLCAP00010050094	Ras-GEF domain-containing protein.	Rap guanine nucleotide exchange factor (GEF)-like 1.	0.479
ENSLCAP00010049166	ENSLCAP00010025047	ENSLCAP00010049166	ENSLCAP00010025047	Rap guanine nucleotide exchange factor (GEF) 2.	Ras protein-specific guanine nucleotide-releasing factor 2a.	0.402
ENSLCAP00010049166	LOC108875322	ENSLCAP00010049166	ENSLCAP00010012066	Rap guanine nucleotide exchange factor (GEF) 2.	Uncharacterized protein.	0.402
ENSLCAP00010049166	LOC108877024	ENSLCAP00010049166	ENSLCAP00010052471	Rap guanine nucleotide exchange factor (GEF) 2.	Uncharacterized protein.	0.402
ENSLCAP00010049166	LOC108886034	ENSLCAP00010049166	ENSLCAP00010000448	Rap guanine nucleotide exchange factor (GEF) 2.	Uncharacterized protein.	0.520
ENSLCAP00010049166	RASGEF1B	ENSLCAP00010049166	ENSLCAP00010036378	Rap guanine nucleotide exchange factor (GEF) 2.	Uncharacterized protein.	0.520
ENSLCAP00010049166	Ralgps1	ENSLCAP00010049166	ENSLCAP00010028710	Rap guanine nucleotide exchange factor (GEF) 2.	Ras-GEF domain-containing protein.	0.429
ENSLCAP00010049166	Rasgrf2	ENSLCAP00010049166	ENSLCAP00010008722	Rap guanine nucleotide exchange factor (GEF) 2.	Ras protein specific guanine nucleotide releasing factor 2.	0.402
ENSLCAP00010049166	Sos1	ENSLCAP00010049166	ENSLCAP00010025565	Rap guanine nucleotide exchange factor (GEF) 2.	Son of sevenless homolog 1 (Drosophila).	0.402
ENSLCAP00010049166	Sos2	ENSLCAP00010049166	ENSLCAP00010050735	Rap guanine nucleotide exchange factor (GEF) 2.	Son of sevenless homolog 2 (Drosophila).	0.402
ENSLCAP00010049166	ralgps2	ENSLCAP00010049166	ENSLCAP00010018001	Rap guanine nucleotide exchange factor (GEF) 2.	Uncharacterized protein.	0.405
ENSLCAP00010049166	rapgef6	ENSLCAP00010049166	ENSLCAP00010029274	Rap guanine nucleotide exchange factor (GEF) 2.	Uncharacterized protein.	0.668
LOC108875322	ENSLCAP00010025047	ENSLCAP00010012066	ENSLCAP00010025047	Uncharacterized protein.	Ras protein-specific guanine nucleotide-releasing factor 2a.	0.474
LOC108875322	ENSLCAP00010049166	ENSLCAP00010012066	ENSLCAP00010049166	Uncharacterized protein.	Rap guanine nucleotide exchange factor (GEF) 2.	0.402
LOC108875322	LOC108877024	ENSLCAP00010012066	ENSLCAP00010052471	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC108875322	Rasgrf2	ENSLCAP00010012066	ENSLCAP00010008722	Uncharacterized protein.	Ras protein specific guanine nucleotide releasing factor 2.	0.945
LOC108877024	ENSLCAP00010025047	ENSLCAP00010052471	ENSLCAP00010025047	Uncharacterized protein.	Ras protein-specific guanine nucleotide-releasing factor 2a.	0.474