STRINGSTRING
ccnd1 ccnd1 LOC108888178 LOC108888178 Cdc20b Cdc20b mad2l2 mad2l2 ENSLCAP00010001596 ENSLCAP00010001596 ENSLCAP00010002675 ENSLCAP00010002675 LOC108883827 LOC108883827 E2F3 E2F3 dbf4 dbf4 anapc10 anapc10 ENSLCAP00010004596 ENSLCAP00010004596 mdm2 mdm2 wee1 wee1 Orc5 Orc5 LOC108886219 LOC108886219 cdc45 cdc45 ENSLCAP00010007435 ENSLCAP00010007435 pcna pcna LOC108891223 LOC108891223 mcm6 mcm6 CCNB2 CCNB2 hdac1 hdac1 ENSLCAP00010009748 ENSLCAP00010009748 LOC108896340 LOC108896340 mcm4 mcm4 mcm3 mcm3 LOC108882441 LOC108882441 abl1 abl1 cdc26 cdc26 LOC108882464 LOC108882464 e2f1 e2f1 SMAD4 SMAD4 cdk2 cdk2 cdc23 cdc23 LOC108880253 LOC108880253 LOC108883053 LOC108883053 ENSLCAP00010015247 ENSLCAP00010015247 LOC108876160 LOC108876160 LOC108879980 LOC108879980 cdkn1b cdkn1b GADD45A GADD45A TGFB3 TGFB3 LOC108883334 LOC108883334 LOC108884668 LOC108884668 ccne1 ccne1 anapc11 anapc11 LOC108901859 LOC108901859 anapc13 anapc13 Smc3 Smc3 rbx1 rbx1 cdc16 cdc16 Anapc2 Anapc2 LOC108901307 LOC108901307 LOC108900731 LOC108900731 mcm2 mcm2 mad1l1 mad1l1 LOC108876085 LOC108876085 Cdc25b Cdc25b Cdk1 Cdk1 cdc20 cdc20 skp1 skp1 stag1 stag1 Orc4 Orc4 LOC108898131 LOC108898131 LOC108882190 LOC108882190 LOC108879927 LOC108879927 LOC108901136 LOC108901136 LOC108891918 LOC108891918 anapc4 anapc4 LOC108878489 LOC108878489 YWHAB YWHAB ttk ttk ENSLCAP00010034308 ENSLCAP00010034308 FZR1 FZR1 LOC108888694 LOC108888694 LOC108893914 LOC108893914 ccnd3 ccnd3 bub1 bub1 ENSLCAP00010039837 ENSLCAP00010039837 LOC108901190 LOC108901190 ENSLCAP00010040474 ENSLCAP00010040474 Cdk6 Cdk6 LOC108884383 LOC108884383 tgfb3 tgfb3 LOC108872574 LOC108872574 cdc27 cdc27 LOC108876274 LOC108876274 cdk4 cdk4 anapc5 anapc5 mcm5 mcm5 Orc3 Orc3 bub3 bub3 Smc1a Smc1a GADD45B-2 GADD45B-2 ccna1 ccna1 mcm7 mcm7 LOC108883699 LOC108883699 ENSLCAP00010048363 ENSLCAP00010048363 cdc7 cdc7 HDAC2 HDAC2 ywhaq ywhaq PLK1 PLK1 ccnb1 ccnb1 LOC108874403 LOC108874403 LOC108879779 LOC108879779 tfdp1 tfdp1 LOC108900426 LOC108900426 LOC108872758 LOC108872758 LOC108890605 LOC108890605 ccnb3 ccnb3 LOC108893774 LOC108893774 ENSLCAP00010053862 ENSLCAP00010053862 LOC108881353 LOC108881353 cdkn2d cdkn2d cul1 cul1 rb1 rb1 cdc14a cdc14a ccna2 ccna2 LOC108880872 LOC108880872 Cdkn2c Cdkn2c gsk3b gsk3b LOC108882499 LOC108882499 anapc7 anapc7 ccnh ccnh cdk7 cdk7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ccnd1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
LOC10888817814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
Cdc20bWD_REPEATS_REGION domain-containing protein. (387 aa)
mad2l2HORMA domain-containing protein. (210 aa)
ENSLCAP00010001596Mothers against decapentaplegic homolog. (531 aa)
ENSLCAP00010002675Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (556 aa)
LOC108883827WD_REPEATS_REGION domain-containing protein. (487 aa)
E2F3E2F_TDP domain-containing protein. (443 aa)
dbf4Uncharacterized protein. (628 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)
ENSLCAP00010004596E2F_TDP domain-containing protein. (90 aa)
mdm2Uncharacterized protein. (511 aa)
wee1Wee1-like protein kinase. (620 aa)
Orc5Origin recognition complex, subunit 5. (449 aa)
LOC108886219Uncharacterized protein; Belongs to the cyclin family. (294 aa)
cdc45Uncharacterized protein. (568 aa)
ENSLCAP00010007435Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (264 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
LOC108891223HORMA domain-containing protein. (202 aa)
mcm6DNA helicase; Belongs to the MCM family. (832 aa)
CCNB2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (397 aa)
hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
ENSLCAP00010009748Stromal antigen 2b. (1276 aa)
LOC108896340Mothers against decapentaplegic homolog. (616 aa)
mcm4DNA helicase; Belongs to the MCM family. (860 aa)
mcm3DNA helicase; Belongs to the MCM family. (815 aa)
LOC108882441Uncharacterized protein. (556 aa)
abl1Tyrosine-protein kinase. (1148 aa)
cdc26Uncharacterized protein. (95 aa)
LOC108882464Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (385 aa)
e2f1E2F_TDP domain-containing protein. (454 aa)
SMAD4Mothers against decapentaplegic homolog. (524 aa)
cdk2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
cdc23Uncharacterized protein. (600 aa)
LOC108880253Uncharacterized protein. (511 aa)
LOC108883053Uncharacterized protein. (215 aa)
ENSLCAP00010015247Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (417 aa)
LOC108876160Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
LOC108879980Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (380 aa)
cdkn1bUncharacterized protein. (185 aa)
GADD45ARibosomal_L7Ae domain-containing protein. (157 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
LOC108883334Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (940 aa)
LOC108884668Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (395 aa)
ccne1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (433 aa)
anapc11RING-type domain-containing protein. (84 aa)
LOC108901859Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (366 aa)
anapc13Uncharacterized protein. (74 aa)
Smc3Structural maintenance of chromosomes protein. (1227 aa)
rbx1RING-type domain-containing protein. (108 aa)
cdc16TPR_REGION domain-containing protein. (620 aa)
Anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (872 aa)
LOC108901307SCD domain-containing protein. (1183 aa)
LOC108900731F-box domain-containing protein. (421 aa)
mcm2DNA helicase; Belongs to the MCM family. (916 aa)
mad1l1Uncharacterized protein. (722 aa)
LOC10887608514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
Cdc25bRhodanese domain-containing protein. (385 aa)
Cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (331 aa)
cdc20WD_REPEATS_REGION domain-containing protein. (502 aa)
skp1Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
stag1SCD domain-containing protein. (1262 aa)
Orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (462 aa)
LOC10889813114_3_3 domain-containing protein; Belongs to the 14-3-3 family. (252 aa)
LOC108882190Uncharacterized protein. (536 aa)
LOC108879927Uncharacterized protein. (184 aa)
LOC108901136Ribosomal_L7Ae domain-containing protein. (155 aa)
LOC10889191814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (258 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (804 aa)
LOC108878489Mothers against decapentaplegic homolog. (467 aa)
YWHAB14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (249 aa)
ttkProtein kinase domain-containing protein. (1004 aa)
ENSLCAP00010034308Uncharacterized protein. (427 aa)
FZR1WD_REPEATS_REGION domain-containing protein. (496 aa)
LOC108888694Uncharacterized protein. (635 aa)
LOC10889391414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
ccnd3Uncharacterized protein; Belongs to the cyclin family. (318 aa)
bub1Uncharacterized protein. (1297 aa)
ENSLCAP00010039837Uncharacterized protein. (160 aa)
LOC108901190Uncharacterized protein. (651 aa)
ENSLCAP00010040474Si:ch211-160f23.5. (422 aa)
Cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (313 aa)
LOC10888438314_3_3 domain-containing protein; Belongs to the 14-3-3 family. (252 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
LOC108872574Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
cdc27Uncharacterized protein. (808 aa)
LOC10887627414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (251 aa)
cdk4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (306 aa)
anapc5Uncharacterized protein. (773 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
Orc3Origin recognition complex, subunit 3. (712 aa)
bub3WD_REPEATS_REGION domain-containing protein. (326 aa)
Smc1aStructural maintenance of chromosomes protein. (1232 aa)
GADD45B-2Ribosomal_L7Ae domain-containing protein. (160 aa)
ccna1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (416 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (729 aa)
LOC108883699Ribosomal_L7Ae domain-containing protein. (163 aa)
ENSLCAP00010048363SCD domain-containing protein. (887 aa)
cdc7Protein kinase domain-containing protein. (610 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (507 aa)
ywhaq14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (257 aa)
PLK1Serine/threonine-protein kinase PLK. (569 aa)
ccnb1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (404 aa)
LOC108874403BHLH domain-containing protein. (381 aa)
LOC108879779Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (293 aa)
tfdp1Transcription factor. (413 aa)
LOC108900426E2F_TDP domain-containing protein. (329 aa)
LOC108872758Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (300 aa)
LOC108890605Uncharacterized protein. (185 aa)
ccnb3Uncharacterized protein; Belongs to the cyclin family. (431 aa)
LOC108893774SCD domain-containing protein. (1226 aa)
ENSLCAP00010053862Uncharacterized protein. (205 aa)
LOC108881353WD_REPEATS_REGION domain-containing protein. (495 aa)
cdkn2dANK_REP_REGION domain-containing protein. (164 aa)
cul1CULLIN_2 domain-containing protein; Belongs to the cullin family. (776 aa)
rb1Uncharacterized protein. (913 aa)
cdc14aUncharacterized protein. (619 aa)
ccna2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (436 aa)
LOC108880872Structural maintenance of chromosomes protein. (1250 aa)
Cdkn2cANK_REP_REGION domain-containing protein. (118 aa)
gsk3bProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (425 aa)
LOC108882499Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (573 aa)
anapc7Uncharacterized protein. (574 aa)
ccnhCYCLIN domain-containing protein; Belongs to the cyclin family. (324 aa)
cdk7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (343 aa)
Your Current Organism:
Lates calcarifer
NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch
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