node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CUP47143.1 | CUQ02419.1 | ERS852554_00850 | ERS852554_02647 | Acyl carrier protein phosphodiesterase. | Siderophore (surfactin) biosynthesis regulatory protein; Belongs to the P-Pant transferase superfamily. | 0.900 |
CUP47143.1 | coaBC | ERS852554_00850 | ERS852554_03541 | Acyl carrier protein phosphodiesterase. | Phosphopantothenoylcysteine decarboxylase%3B phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.900 |
CUP47143.1 | coaD | ERS852554_00850 | ERS852554_01580 | Acyl carrier protein phosphodiesterase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.904 |
CUP47143.1 | coaW | ERS852554_00850 | ERS852554_02135 | Acyl carrier protein phosphodiesterase. | Pantothenate kinase. | 0.900 |
CUP47143.1 | coaX | ERS852554_00850 | ERS852554_02161 | Acyl carrier protein phosphodiesterase. | Transcriptional acitvator%2C Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.900 |
CUQ02419.1 | CUP47143.1 | ERS852554_02647 | ERS852554_00850 | Siderophore (surfactin) biosynthesis regulatory protein; Belongs to the P-Pant transferase superfamily. | Acyl carrier protein phosphodiesterase. | 0.900 |
CUQ02419.1 | coaE | ERS852554_02647 | ERS852554_02253 | Siderophore (surfactin) biosynthesis regulatory protein; Belongs to the P-Pant transferase superfamily. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.906 |
CUQ08135.1 | panB | ERS852554_02844 | ERS852554_00147 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.927 |
CUQ08135.1 | panC | ERS852554_02844 | ERS852554_03400 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.927 |
coaBC | CUP47143.1 | ERS852554_03541 | ERS852554_00850 | Phosphopantothenoylcysteine decarboxylase%3B phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Acyl carrier protein phosphodiesterase. | 0.900 |
coaBC | coaD | ERS852554_03541 | ERS852554_01580 | Phosphopantothenoylcysteine decarboxylase%3B phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.934 |
coaBC | coaE | ERS852554_03541 | ERS852554_02253 | Phosphopantothenoylcysteine decarboxylase%3B phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.472 |
coaBC | coaW | ERS852554_03541 | ERS852554_02135 | Phosphopantothenoylcysteine decarboxylase%3B phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase. | 0.921 |
coaBC | coaX | ERS852554_03541 | ERS852554_02161 | Phosphopantothenoylcysteine decarboxylase%3B phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Transcriptional acitvator%2C Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.924 |
coaBC | panB | ERS852554_03541 | ERS852554_00147 | Phosphopantothenoylcysteine decarboxylase%3B phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.458 |
coaBC | panC | ERS852554_03541 | ERS852554_03400 | Phosphopantothenoylcysteine decarboxylase%3B phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.891 |
coaD | CUP47143.1 | ERS852554_01580 | ERS852554_00850 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Acyl carrier protein phosphodiesterase. | 0.904 |
coaD | coaBC | ERS852554_01580 | ERS852554_03541 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase%3B phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.934 |
coaD | coaE | ERS852554_01580 | ERS852554_02253 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.935 |
coaD | coaW | ERS852554_01580 | ERS852554_02135 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Pantothenate kinase. | 0.913 |