STRINGSTRING
rlmE rlmE KAJ05034.1 KAJ05034.1 KAJ05035.1 KAJ05035.1 KAJ04675.1 KAJ04675.1 KAJ04702.1 KAJ04702.1 rne rne KAJ04713.1 KAJ04713.1 rnd rnd KAJ04736.1 KAJ04736.1 rsmA rsmA KAJ04758.1 KAJ04758.1 tyrS tyrS ihfA ihfA argS argS KAJ04784.1 KAJ04784.1 KAJ04785.1 KAJ04785.1 KAJ04787.1 KAJ04787.1 cysS cysS KAJ04798.1 KAJ04798.1 ung ung lexA lexA gltX gltX KAJ04840.1 KAJ04840.1 KAJ04845.1 KAJ04845.1 radA radA KAJ04876.1 KAJ04876.1 KAJ04934.1 KAJ04934.1 KAJ04949.1 KAJ04949.1 KAJ04950.1 KAJ04950.1 KAJ04958.1 KAJ04958.1 rsmH rsmH glyS glyS KAJ05016.1 KAJ05016.1 glyQ glyQ KAJ04298.1 KAJ04298.1 KAJ04300.1 KAJ04300.1 KAJ04325.1 KAJ04325.1 rlmH rlmH KAJ04393.1 KAJ04393.1 nth nth KAJ04409.1 KAJ04409.1 KAJ04415.1 KAJ04415.1 KAJ04432.1 KAJ04432.1 KAJ04433.1 KAJ04433.1 KAJ04434.1 KAJ04434.1 dnaE2 dnaE2 KAJ04437.1 KAJ04437.1 pheS pheS pheT pheT KAJ04485.1 KAJ04485.1 KAJ04487.1 KAJ04487.1 recR recR dnaX dnaX trmD trmD rimM rimM smc smc fmt fmt rnhA rnhA KAJ04587.1 KAJ04587.1 rpoZ rpoZ rnc rnc recO recO parC parC KAJ04626.1 KAJ04626.1 aspS aspS trpS trpS rsmI rsmI KAJ04041.1 KAJ04041.1 KAJ04048.1 KAJ04048.1 KAJ04063.1 KAJ04063.1 gltX-2 gltX-2 lysK lysK KAJ04106.1 KAJ04106.1 uvrB uvrB KAJ04125.1 KAJ04125.1 KAJ04137.1 KAJ04137.1 KAJ04238.1 KAJ04238.1 KAJ03778.1 KAJ03778.1 xseB xseB KAJ03816.1 KAJ03816.1 KAJ03832.1 KAJ03832.1 KAJ03833.1 KAJ03833.1 KAJ03850.1 KAJ03850.1 dnaJ dnaJ KAJ03860.1 KAJ03860.1 nusA nusA KAJ03880.1 KAJ03880.1 KAJ03883.1 KAJ03883.1 mutS mutS rph rph rsmG rsmG mnmG mnmG mnmE mnmE rho rho dnaQ dnaQ KAJ03918.1 KAJ03918.1 KAJ03925.1 KAJ03925.1 KAJ03928.1 KAJ03928.1 tsaD tsaD KAJ03945.1 KAJ03945.1 gyrB gyrB recF recF KAJ03996.1 KAJ03996.1 dnaA dnaA mutM mutM rlmN rlmN rnr rnr KAJ03563.1 KAJ03563.1 KAJ03590.1 KAJ03590.1 KAJ03603.1 KAJ03603.1 polA polA KAJ03612.1 KAJ03612.1 KAJ03621.1 KAJ03621.1 rnhB rnhB KAJ03648.1 KAJ03648.1 KAJ03652.1 KAJ03652.1 KAJ03664.1 KAJ03664.1 KAJ03668.1 KAJ03668.1 leuS leuS KAJ03678.1 KAJ03678.1 KAJ03703.1 KAJ03703.1 pnp pnp truB truB rbfA rbfA KAJ03715.1 KAJ03715.1 mutL mutL KAJ03736.1 KAJ03736.1 dinB dinB alaS alaS recA recA KAJ03336.1 KAJ03336.1 gyrA gyrA trmJ trmJ psuG psuG mfd mfd KAJ03382.1 KAJ03382.1 KAJ03391.1 KAJ03391.1 trmFO trmFO KAJ03424.1 KAJ03424.1 ligA ligA mnmA mnmA miaA miaA KAJ03452.1 KAJ03452.1 xerC xerC KAJ03486.1 KAJ03486.1 KAJ03487.1 KAJ03487.1 KAJ03491.1 KAJ03491.1 uvrA uvrA KAJ03248.1 KAJ03248.1 KAJ03271.1 KAJ03271.1 KAJ03274.1 KAJ03274.1 tgt tgt KAJ03286.1 KAJ03286.1 KAJ03287.1 KAJ03287.1 KAJ03289.1 KAJ03289.1 KAJ03290.1 KAJ03290.1 KAJ02891.1 KAJ02891.1 KAJ02898.1 KAJ02898.1 KAJ02909.1 KAJ02909.1 ileS ileS truA truA KAJ02933.1 KAJ02933.1 ihfB ihfB trmB trmB ybeY ybeY miaB miaB KAJ02963.1 KAJ02963.1 tdk tdk KAJ03026.1 KAJ03026.1 KAJ03082.1 KAJ03082.1 KAJ02752.1 KAJ02752.1 hisS hisS KAJ02758.1 KAJ02758.1 KAJ02815.1 KAJ02815.1 KAJ02824.1 KAJ02824.1 rimO rimO KAJ02841.1 KAJ02841.1 dtd dtd KAJ02670.1 KAJ02670.1 tadA tadA KAJ02706.1 KAJ02706.1 KAJ02453.1 KAJ02453.1 KAJ02454.1 KAJ02454.1 rpoH rpoH KAJ02460.1 KAJ02460.1 KAJ02468.1 KAJ02468.1 rpoD rpoD dnaG dnaG KAJ02496.1 KAJ02496.1 metG metG valS valS KAJ02570.1 KAJ02570.1 KAJ02581.1 KAJ02581.1 KAJ02573.1 KAJ02573.1 KAJ02574.1 KAJ02574.1 KAJ02575.1 KAJ02575.1 KAJ02312.1 KAJ02312.1 KAJ02313.1 KAJ02313.1 KAJ02316.1 KAJ02316.1 proS proS KAJ02327.1 KAJ02327.1 parE parE thrS thrS rlmJ rlmJ KAJ02425.1 KAJ02425.1 KAJ02208.1 KAJ02208.1 KAJ02229.1 KAJ02229.1 KAJ02244.1 KAJ02244.1 uvrC uvrC KAJ02110.1 KAJ02110.1 KAJ02116.1 KAJ02116.1 xerC-2 xerC-2 priA priA ruvC ruvC ruvA ruvA ruvB ruvB tilS tilS KAJ02146.1 KAJ02146.1 topA topA KAJ02005.1 KAJ02005.1 KAJ02006.1 KAJ02006.1 KAJ02041.1 KAJ02041.1 KAJ02065.1 KAJ02065.1 KAJ02074.1 KAJ02074.1 KAJ01945.1 KAJ01945.1 dusA dusA KAJ01878.1 KAJ01878.1 serS serS KAJ01868.1 KAJ01868.1 KAJ01723.1 KAJ01723.1 rpoA rpoA KAJ01682.1 KAJ01682.1 KAJ01684.1 KAJ01684.1 ttcA ttcA rnpA rnpA KAJ01643.1 KAJ01643.1 KAJ01605.1 KAJ01605.1 xseA xseA KAJ01580.1 KAJ01580.1 nusG nusG rpoB rpoB rpoC rpoC KAJ01514.1 KAJ01514.1 KAJ01516.1 KAJ01516.1 KAJ01509.1 KAJ01509.1 KAJ01477.1 KAJ01477.1 KAJ01489.1 KAJ01489.1 KAJ01491.1 KAJ01491.1 KAJ01459.1 KAJ01459.1 KAJ01460.1 KAJ01460.1 KAJ01446.1 KAJ01446.1 KAJ01447.1 KAJ01447.1 KAJ01450.1 KAJ01450.1 KAJ01420.1 KAJ01420.1 KAJ01414.1 KAJ01414.1 KAJ01406.1 KAJ01406.1 KAJ01405.1 KAJ01405.1 KAJ01403.1 KAJ01403.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rlmE23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (244 aa)
KAJ05034.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (97 aa)
KAJ05035.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (79 aa)
KAJ04675.1Ala-tRNA(Pro) hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
KAJ04702.1Preprotein translocase subunit TatB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (75 aa)
rneRibonuclease; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (963 aa)
KAJ04713.1DNA repair photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
rndRibonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (385 aa)
KAJ04736.1DNA polymerase III subunit chi; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
rsmA16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (283 aa)
KAJ04758.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (416 aa)
ihfAIntegration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (100 aa)
argSarginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
KAJ04784.1Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
KAJ04785.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
KAJ04787.13-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa)
KAJ04798.1Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1219 aa)
unguracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (219 aa)
lexALexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (233 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (466 aa)
KAJ04840.1FkbM family methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
KAJ04845.1DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (494 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (455 aa)
KAJ04876.1Metallo-beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
KAJ04934.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
KAJ04949.1BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (85 aa)
KAJ04950.1Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
KAJ04958.1DNA recombination protein RecN; May be involved in recombinational repair of damaged DNA. (549 aa)
rsmH16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (329 aa)
glySglycyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (742 aa)
KAJ05016.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
glyQglycyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
KAJ04298.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (417 aa)
KAJ04300.1RNA polymerase sigma factor RpoE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (210 aa)
KAJ04325.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
rlmH50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa)
KAJ04393.1DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (214 aa)
KAJ04409.16-O-methylguanine DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
KAJ04415.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
KAJ04432.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (685 aa)
KAJ04433.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
KAJ04434.1Protein ImuB; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
dnaE2DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1103 aa)
KAJ04437.1tRNA 2-selenouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SelU family. (349 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (357 aa)
pheTphenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (799 aa)
KAJ04485.1Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RNase T2 family. (214 aa)
KAJ04487.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
recRRecombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (197 aa)
dnaXDNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (581 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (262 aa)
rimM16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (173 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1151 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (304 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (150 aa)
KAJ04587.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (117 aa)
rncRibonuclease; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (228 aa)
recODNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. (244 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (767 aa)
KAJ04626.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (616 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (338 aa)
rsmI16S rRNA methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (287 aa)
KAJ04041.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family. (125 aa)
KAJ04048.1RNA polymerase sigma 70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (292 aa)
KAJ04063.1Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)
gltX-2glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (445 aa)
lysKlysine--tRNA ligase; Class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (526 aa)
KAJ04106.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (738 aa)
KAJ04125.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
KAJ04137.1DNA helicase; Unwinds double stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
KAJ04238.1Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa)
KAJ03778.12-methylthioadenine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (80 aa)
KAJ03816.1Epoxyqueuosine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
KAJ03832.1PaaX family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
KAJ03833.13'-5' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
KAJ03850.1Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (384 aa)
KAJ03860.1NTP pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family. (132 aa)
nusATranscription elongation factor NusA; Participates in both transcription termination and antitermination. (542 aa)
KAJ03880.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (406 aa)
KAJ03883.1poly(A) polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (385 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (873 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (237 aa)
rsmG16S rRNA methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (202 aa)
mnmGtRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (623 aa)
mnmEtRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (429 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (423 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (228 aa)
KAJ03918.1DNA mismatch repair protein MutS; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
KAJ03925.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (985 aa)
KAJ03928.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
tsaDtRNA threonylcarbamoyladenosine biosynthesis protein Gcp; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (362 aa)
KAJ03945.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (804 aa)
recFRecombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (365 aa)
KAJ03996.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa)
dnaAChromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (453 aa)
mutM5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (283 aa)
rlmNRNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (394 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (751 aa)
KAJ03563.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0176 family. (297 aa)
KAJ03590.1ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (681 aa)
KAJ03603.1Hydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
polADNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (933 aa)
KAJ03612.1DNA-directed RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (160 aa)
KAJ03621.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (204 aa)
KAJ03648.1Modification methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (367 aa)
KAJ03652.1Adenine glycosylase; Adenine glycosylase active on G-A mispairs. (355 aa)
KAJ03664.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)
KAJ03668.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
leuSleucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (848 aa)
KAJ03678.1Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
KAJ03703.1Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (215 aa)
pnpPolynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (711 aa)
truBPseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (301 aa)
rbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (138 aa)
KAJ03715.116S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (424 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (613 aa)
KAJ03736.1Recombinase RmuC; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (378 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (882 aa)
recARecombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (354 aa)
KAJ03336.1SAM-dependent methlyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (386 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (919 aa)
trmJRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (250 aa)
psuGPseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (303 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1154 aa)
KAJ03382.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (187 aa)
KAJ03391.1tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (328 aa)
trmFOtRNA (uracil-5-)-methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (445 aa)
KAJ03424.1glutamyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (288 aa)
ligANAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (706 aa)
mnmAThiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (380 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (296 aa)
KAJ03452.1Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (174 aa)
xerCRecombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (324 aa)
KAJ03486.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
KAJ03487.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
KAJ03491.1prolyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
uvrAUvrABC system subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (958 aa)
KAJ03248.1BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (78 aa)
KAJ03271.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa)
KAJ03274.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (375 aa)
KAJ03286.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
KAJ03287.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (336 aa)
KAJ03289.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
KAJ03290.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
KAJ02891.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (425 aa)
KAJ02898.1Ribonuclease G; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
KAJ02909.1Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (151 aa)
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (974 aa)
truAPseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (255 aa)
KAJ02933.1uracil-DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
ihfBIntegration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (94 aa)
trmBtRNA (guanine-N7)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (233 aa)
ybeYrRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (171 aa)
miaB(dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (440 aa)
KAJ02963.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
KAJ03026.1tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
KAJ03082.1DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
KAJ02752.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1168 aa)
hisShistidyl-tRNA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (541 aa)
KAJ02758.1Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (755 aa)
KAJ02815.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)
KAJ02824.1Peptidase M22; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
rimORibosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (460 aa)
KAJ02841.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (400 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (148 aa)
KAJ02670.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (281 aa)
tadAdCMP deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (151 aa)
KAJ02706.1Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
KAJ02453.1mRNA 3'-end processing factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
KAJ02454.1ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
rpoHRNA polymerase sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (298 aa)
KAJ02460.1Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (343 aa)
KAJ02468.1Antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (160 aa)
rpoDRNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (662 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (655 aa)
KAJ02496.1Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (196 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (570 aa)
valSvaline--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (972 aa)
KAJ02570.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (339 aa)
KAJ02581.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (195 aa)
KAJ02573.1Type II restriction-modification system restriction subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (602 aa)
KAJ02574.1DNA glycosylase; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. (150 aa)
KAJ02575.1Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
KAJ02312.1Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
KAJ02313.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
KAJ02316.1Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
proSproline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. (446 aa)
KAJ02327.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (652 aa)
thrSthreonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (648 aa)
rlmJProtein involved in catabolism of external DNA; Specifically methylates the adenine in position 2030 of 23S rRNA. (258 aa)
KAJ02425.1Recombinase RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (579 aa)
KAJ02208.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (71 aa)
KAJ02229.1Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (313 aa)
KAJ02244.116S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (242 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (621 aa)
KAJ02110.1Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa)
KAJ02116.1ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (804 aa)
xerC-2Recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (305 aa)
priAPrimosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (731 aa)
ruvCHolliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (168 aa)
ruvAATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (223 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (339 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (418 aa)
KAJ02146.1Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (878 aa)
KAJ02005.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
KAJ02006.1RNA polymerase sigma70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (227 aa)
KAJ02041.1Flagellum biosynthesis protein FlbT; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
KAJ02065.1Replication protein RepB; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
KAJ02074.1Recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
KAJ01945.13'-5' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
dusAtRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (345 aa)
KAJ01878.1Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (161 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa)
KAJ01868.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (258 aa)
KAJ01723.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (338 aa)
KAJ01682.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
KAJ01684.1Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (349 aa)
ttcAtRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (283 aa)
rnpARibonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (142 aa)
KAJ01643.1Plasmid replication initiator; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
KAJ01605.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (515 aa)
KAJ01580.1Dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
nusGAntitermination protein NusG; Participates in transcription elongation, termination and antitermination. (177 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1379 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1415 aa)
KAJ01514.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
KAJ01516.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (403 aa)
KAJ01509.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (315 aa)
KAJ01477.1DNA invertase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
KAJ01489.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
KAJ01491.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
KAJ01459.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
KAJ01460.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
KAJ01446.1Recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
KAJ01447.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
KAJ01450.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
KAJ01420.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
KAJ01414.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
KAJ01406.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
KAJ01405.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
KAJ01403.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
Your Current Organism:
Sulfitobacter mediterraneus
NCBI taxonomy Id: 83219
Other names: ATCC 700856, DSM 12244, JCM 21792, S. mediterraneus, strain CH-B427
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