STRINGSTRING
dinF dinF nrnA nrnA rbfA rbfA infB infB Rv2840c Rv2840c nusA nusA rimP rimP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dinFRv2836c, (MTCY16B7.06), len: 439 aa. Possible dinF,DNA-damage-inducible protein F, integral membrane protein,similar to others e.g. BAB38450|ECS5027|AAG59243 from Escherichia coli strain O157:H7 (459 aa), FASTA scores: opt: 501, E(): 2.7e-21, (29.55% identity in 443 aa overlap); P28303|DINF_ECOLI|B4044 from Escherichia coli strain K12 (459 aa), FASTA scores: opt: 491, E(): 1e-20,(29.35% identity in 443 aa overlap); Q98B90|MLR5680 from Rhizobium loti (Mesorhizobium loti) (471 aa), FASTA scores: opt: 466, E(): 2.7e-19, (30.7% identity in 433 aa overlap); etc. But also similar or highly s [...] (439 aa)
nrnAConserved protein; Bifunctional enzyme which has both oligoribonuclease and pAp- phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for 2-mers. Also degrades 24-mers. Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. (336 aa)
rbfAProbable ribosome-binding factor a RbfA (P15B protein); One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (183 aa)
infBProbable translation initiation factor if-2 InfB; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (900 aa)
Rv2840cRv2840c, (MTCY16B7.02), len: 99 aa. Conserved hypothetical protein, equivalent to Q9Z5J0|ML1557|MLCB596.13 hypothetical 11.6 KDA protein from Mycobacterium leprae (106 aa), FASTA scores: opt: 501, E(): 2.3e-29, (501% identity in 96 aa overlap). Also highly similar to other hypothetical proteins e.g. Q9KYR0|SC5H4.29 from Streptomyces coelicolor (101 aa), FASTA scores: opt: 256, E(): 1.4e-11, (50.6% identity in 81 aa overlap); Q9APM9 from Myxococcus xanthus (111 aa), FASTA scores: opt: 174, E(): 1.3e-05, (42.25% identity in 97 aa overlap); and similar to to others e.g. N-terminus of CAC4 [...] (99 aa)
nusAProbable N utilization substance protein A NusA; Participates in both transcription termination and antitermination; Belongs to the NusA family. (347 aa)
rimPConserved protein; Required for maturation of 30S ribosomal subunits. (183 aa)
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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