node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0547c | Rv1414 | Rv0547c | Rv1414 | Possible oxidoreductase; Rv0547c, (MTCY25D10.26c), len: 294 aa. Possible oxidoreductase, similar to various oxidoreductases e.g. fatty acyl-CoA reductase from Acinetobacter calcoaceticus (295 aa); NP_280196.1|NC_002607 3-oxoacyl-[acyl-carrier-protein] reductase from Halobacterium sp. NRC-1 (255 aa); NP_349214.1|NC_003030 Short-chain alcohol dehydrogenase family protein from Clostridium acetobutylicum (255 aa); etc. Also similar to several proteins from Mycobacterium tuberculosis e.g. Y04M_MYCTU|Q10783 putative oxidoreductase (341 aa), FASTA scores: opt: 644, E(): 0, (46.1% identity in [...] | Rv1414, (MTCY21B4.31), len: 133 aa. Conserved hypothetical protein, similar to C-terminal part of AB010956|AB010956_1 novel metal-activated pyridoxal enzyme from Arthrobacter sp. (379 aa), FASTA scores: opt: 163,E(): 0.00063, (32.1% identity in 112 aa overlap). Rv1413 is similar to N-terminal part of same enzyme suggesting possible frameshift. Sequence has been checked and no errors found, it is identical in Mycobacterium bovis strain AF2122/97 and in Mycobacterium tuberculosis CDC1551. | 0.870 |
Rv0547c | Rv2308 | Rv0547c | Rv2308 | Possible oxidoreductase; Rv0547c, (MTCY25D10.26c), len: 294 aa. Possible oxidoreductase, similar to various oxidoreductases e.g. fatty acyl-CoA reductase from Acinetobacter calcoaceticus (295 aa); NP_280196.1|NC_002607 3-oxoacyl-[acyl-carrier-protein] reductase from Halobacterium sp. NRC-1 (255 aa); NP_349214.1|NC_003030 Short-chain alcohol dehydrogenase family protein from Clostridium acetobutylicum (255 aa); etc. Also similar to several proteins from Mycobacterium tuberculosis e.g. Y04M_MYCTU|Q10783 putative oxidoreductase (341 aa), FASTA scores: opt: 644, E(): 0, (46.1% identity in [...] | Rv2308, (MTCY339.01c), len: 238 aa. Conserved hypothetical protein, sharing similarity with O53464|Rv2018|MTV018.05 from Mycobacterium tuberculosis (239 aa), FASTA scores: opt: 142, E(): 0.034, (24.8% identity in 250 aa overlap). As contains possible helix-turn-helix motif at aa 16-37 (Sequence: YVYAEVDKLIGLPAGTAKRWIN) (Score 1169, +3.17 SD), may be a transcriptional regulator. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | 0.870 |
Rv0547c | lucA | Rv0547c | Rv3723 | Possible oxidoreductase; Rv0547c, (MTCY25D10.26c), len: 294 aa. Possible oxidoreductase, similar to various oxidoreductases e.g. fatty acyl-CoA reductase from Acinetobacter calcoaceticus (295 aa); NP_280196.1|NC_002607 3-oxoacyl-[acyl-carrier-protein] reductase from Halobacterium sp. NRC-1 (255 aa); NP_349214.1|NC_003030 Short-chain alcohol dehydrogenase family protein from Clostridium acetobutylicum (255 aa); etc. Also similar to several proteins from Mycobacterium tuberculosis e.g. Y04M_MYCTU|Q10783 putative oxidoreductase (341 aa), FASTA scores: opt: 644, E(): 0, (46.1% identity in [...] | Probable conserved transmembrane protein; Required for the import of both fatty acids and cholesterol during growth in macrophages and in axenic culture. Facilitates the uptake of these lipids by stabilizing protein subunits of the Mce1 and Mce4 multi-subunit transporters, which transport fatty acids and cholesterol, respectively. Required for full virulence in vivo. | 0.861 |
Rv1413 | Rv1414 | Rv1413 | Rv1414 | Rv1413, (MTCY21B4.30), len: 171 aa. Conserved hypothetical protein, similar to part of AB010956|AB010956_1 metal-activated pyridoxal enzyme from Arthrobacter sp. (379 aa), FASTA scores: opt: 187, E(): 0.00026, (29.0% identity in 162 aa overlap). | Rv1414, (MTCY21B4.31), len: 133 aa. Conserved hypothetical protein, similar to C-terminal part of AB010956|AB010956_1 novel metal-activated pyridoxal enzyme from Arthrobacter sp. (379 aa), FASTA scores: opt: 163,E(): 0.00063, (32.1% identity in 112 aa overlap). Rv1413 is similar to N-terminal part of same enzyme suggesting possible frameshift. Sequence has been checked and no errors found, it is identical in Mycobacterium bovis strain AF2122/97 and in Mycobacterium tuberculosis CDC1551. | 0.997 |
Rv1414 | Rv0547c | Rv1414 | Rv0547c | Rv1414, (MTCY21B4.31), len: 133 aa. Conserved hypothetical protein, similar to C-terminal part of AB010956|AB010956_1 novel metal-activated pyridoxal enzyme from Arthrobacter sp. (379 aa), FASTA scores: opt: 163,E(): 0.00063, (32.1% identity in 112 aa overlap). Rv1413 is similar to N-terminal part of same enzyme suggesting possible frameshift. Sequence has been checked and no errors found, it is identical in Mycobacterium bovis strain AF2122/97 and in Mycobacterium tuberculosis CDC1551. | Possible oxidoreductase; Rv0547c, (MTCY25D10.26c), len: 294 aa. Possible oxidoreductase, similar to various oxidoreductases e.g. fatty acyl-CoA reductase from Acinetobacter calcoaceticus (295 aa); NP_280196.1|NC_002607 3-oxoacyl-[acyl-carrier-protein] reductase from Halobacterium sp. NRC-1 (255 aa); NP_349214.1|NC_003030 Short-chain alcohol dehydrogenase family protein from Clostridium acetobutylicum (255 aa); etc. Also similar to several proteins from Mycobacterium tuberculosis e.g. Y04M_MYCTU|Q10783 putative oxidoreductase (341 aa), FASTA scores: opt: 644, E(): 0, (46.1% identity in [...] | 0.870 |
Rv1414 | Rv1413 | Rv1414 | Rv1413 | Rv1414, (MTCY21B4.31), len: 133 aa. Conserved hypothetical protein, similar to C-terminal part of AB010956|AB010956_1 novel metal-activated pyridoxal enzyme from Arthrobacter sp. (379 aa), FASTA scores: opt: 163,E(): 0.00063, (32.1% identity in 112 aa overlap). Rv1413 is similar to N-terminal part of same enzyme suggesting possible frameshift. Sequence has been checked and no errors found, it is identical in Mycobacterium bovis strain AF2122/97 and in Mycobacterium tuberculosis CDC1551. | Rv1413, (MTCY21B4.30), len: 171 aa. Conserved hypothetical protein, similar to part of AB010956|AB010956_1 metal-activated pyridoxal enzyme from Arthrobacter sp. (379 aa), FASTA scores: opt: 187, E(): 0.00026, (29.0% identity in 162 aa overlap). | 0.997 |
Rv1414 | Rv2308 | Rv1414 | Rv2308 | Rv1414, (MTCY21B4.31), len: 133 aa. Conserved hypothetical protein, similar to C-terminal part of AB010956|AB010956_1 novel metal-activated pyridoxal enzyme from Arthrobacter sp. (379 aa), FASTA scores: opt: 163,E(): 0.00063, (32.1% identity in 112 aa overlap). Rv1413 is similar to N-terminal part of same enzyme suggesting possible frameshift. Sequence has been checked and no errors found, it is identical in Mycobacterium bovis strain AF2122/97 and in Mycobacterium tuberculosis CDC1551. | Rv2308, (MTCY339.01c), len: 238 aa. Conserved hypothetical protein, sharing similarity with O53464|Rv2018|MTV018.05 from Mycobacterium tuberculosis (239 aa), FASTA scores: opt: 142, E(): 0.034, (24.8% identity in 250 aa overlap). As contains possible helix-turn-helix motif at aa 16-37 (Sequence: YVYAEVDKLIGLPAGTAKRWIN) (Score 1169, +3.17 SD), may be a transcriptional regulator. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | 0.888 |
Rv1414 | lucA | Rv1414 | Rv3723 | Rv1414, (MTCY21B4.31), len: 133 aa. Conserved hypothetical protein, similar to C-terminal part of AB010956|AB010956_1 novel metal-activated pyridoxal enzyme from Arthrobacter sp. (379 aa), FASTA scores: opt: 163,E(): 0.00063, (32.1% identity in 112 aa overlap). Rv1413 is similar to N-terminal part of same enzyme suggesting possible frameshift. Sequence has been checked and no errors found, it is identical in Mycobacterium bovis strain AF2122/97 and in Mycobacterium tuberculosis CDC1551. | Probable conserved transmembrane protein; Required for the import of both fatty acids and cholesterol during growth in macrophages and in axenic culture. Facilitates the uptake of these lipids by stabilizing protein subunits of the Mce1 and Mce4 multi-subunit transporters, which transport fatty acids and cholesterol, respectively. Required for full virulence in vivo. | 0.860 |
Rv2308 | Rv0547c | Rv2308 | Rv0547c | Rv2308, (MTCY339.01c), len: 238 aa. Conserved hypothetical protein, sharing similarity with O53464|Rv2018|MTV018.05 from Mycobacterium tuberculosis (239 aa), FASTA scores: opt: 142, E(): 0.034, (24.8% identity in 250 aa overlap). As contains possible helix-turn-helix motif at aa 16-37 (Sequence: YVYAEVDKLIGLPAGTAKRWIN) (Score 1169, +3.17 SD), may be a transcriptional regulator. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | Possible oxidoreductase; Rv0547c, (MTCY25D10.26c), len: 294 aa. Possible oxidoreductase, similar to various oxidoreductases e.g. fatty acyl-CoA reductase from Acinetobacter calcoaceticus (295 aa); NP_280196.1|NC_002607 3-oxoacyl-[acyl-carrier-protein] reductase from Halobacterium sp. NRC-1 (255 aa); NP_349214.1|NC_003030 Short-chain alcohol dehydrogenase family protein from Clostridium acetobutylicum (255 aa); etc. Also similar to several proteins from Mycobacterium tuberculosis e.g. Y04M_MYCTU|Q10783 putative oxidoreductase (341 aa), FASTA scores: opt: 644, E(): 0, (46.1% identity in [...] | 0.870 |
Rv2308 | Rv1414 | Rv2308 | Rv1414 | Rv2308, (MTCY339.01c), len: 238 aa. Conserved hypothetical protein, sharing similarity with O53464|Rv2018|MTV018.05 from Mycobacterium tuberculosis (239 aa), FASTA scores: opt: 142, E(): 0.034, (24.8% identity in 250 aa overlap). As contains possible helix-turn-helix motif at aa 16-37 (Sequence: YVYAEVDKLIGLPAGTAKRWIN) (Score 1169, +3.17 SD), may be a transcriptional regulator. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | Rv1414, (MTCY21B4.31), len: 133 aa. Conserved hypothetical protein, similar to C-terminal part of AB010956|AB010956_1 novel metal-activated pyridoxal enzyme from Arthrobacter sp. (379 aa), FASTA scores: opt: 163,E(): 0.00063, (32.1% identity in 112 aa overlap). Rv1413 is similar to N-terminal part of same enzyme suggesting possible frameshift. Sequence has been checked and no errors found, it is identical in Mycobacterium bovis strain AF2122/97 and in Mycobacterium tuberculosis CDC1551. | 0.888 |
Rv2308 | lucA | Rv2308 | Rv3723 | Rv2308, (MTCY339.01c), len: 238 aa. Conserved hypothetical protein, sharing similarity with O53464|Rv2018|MTV018.05 from Mycobacterium tuberculosis (239 aa), FASTA scores: opt: 142, E(): 0.034, (24.8% identity in 250 aa overlap). As contains possible helix-turn-helix motif at aa 16-37 (Sequence: YVYAEVDKLIGLPAGTAKRWIN) (Score 1169, +3.17 SD), may be a transcriptional regulator. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | Probable conserved transmembrane protein; Required for the import of both fatty acids and cholesterol during growth in macrophages and in axenic culture. Facilitates the uptake of these lipids by stabilizing protein subunits of the Mce1 and Mce4 multi-subunit transporters, which transport fatty acids and cholesterol, respectively. Required for full virulence in vivo. | 0.860 |
lucA | Rv0547c | Rv3723 | Rv0547c | Probable conserved transmembrane protein; Required for the import of both fatty acids and cholesterol during growth in macrophages and in axenic culture. Facilitates the uptake of these lipids by stabilizing protein subunits of the Mce1 and Mce4 multi-subunit transporters, which transport fatty acids and cholesterol, respectively. Required for full virulence in vivo. | Possible oxidoreductase; Rv0547c, (MTCY25D10.26c), len: 294 aa. Possible oxidoreductase, similar to various oxidoreductases e.g. fatty acyl-CoA reductase from Acinetobacter calcoaceticus (295 aa); NP_280196.1|NC_002607 3-oxoacyl-[acyl-carrier-protein] reductase from Halobacterium sp. NRC-1 (255 aa); NP_349214.1|NC_003030 Short-chain alcohol dehydrogenase family protein from Clostridium acetobutylicum (255 aa); etc. Also similar to several proteins from Mycobacterium tuberculosis e.g. Y04M_MYCTU|Q10783 putative oxidoreductase (341 aa), FASTA scores: opt: 644, E(): 0, (46.1% identity in [...] | 0.861 |
lucA | Rv1414 | Rv3723 | Rv1414 | Probable conserved transmembrane protein; Required for the import of both fatty acids and cholesterol during growth in macrophages and in axenic culture. Facilitates the uptake of these lipids by stabilizing protein subunits of the Mce1 and Mce4 multi-subunit transporters, which transport fatty acids and cholesterol, respectively. Required for full virulence in vivo. | Rv1414, (MTCY21B4.31), len: 133 aa. Conserved hypothetical protein, similar to C-terminal part of AB010956|AB010956_1 novel metal-activated pyridoxal enzyme from Arthrobacter sp. (379 aa), FASTA scores: opt: 163,E(): 0.00063, (32.1% identity in 112 aa overlap). Rv1413 is similar to N-terminal part of same enzyme suggesting possible frameshift. Sequence has been checked and no errors found, it is identical in Mycobacterium bovis strain AF2122/97 and in Mycobacterium tuberculosis CDC1551. | 0.860 |
lucA | Rv2308 | Rv3723 | Rv2308 | Probable conserved transmembrane protein; Required for the import of both fatty acids and cholesterol during growth in macrophages and in axenic culture. Facilitates the uptake of these lipids by stabilizing protein subunits of the Mce1 and Mce4 multi-subunit transporters, which transport fatty acids and cholesterol, respectively. Required for full virulence in vivo. | Rv2308, (MTCY339.01c), len: 238 aa. Conserved hypothetical protein, sharing similarity with O53464|Rv2018|MTV018.05 from Mycobacterium tuberculosis (239 aa), FASTA scores: opt: 142, E(): 0.034, (24.8% identity in 250 aa overlap). As contains possible helix-turn-helix motif at aa 16-37 (Sequence: YVYAEVDKLIGLPAGTAKRWIN) (Score 1169, +3.17 SD), may be a transcriptional regulator. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | 0.860 |