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accD6 accD6 accD5 accD5 accE5 accE5 accA3 accA3 accD4 accD4 accD3 accD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
accD6Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6; Rv2247, (MTCY427.28), len: 473 aa. AccD6,Acetyl/Propionyl CoA Carboxylase, beta subunit (see citations below), highly similar to e.g. PCCB_RHOSO|Q06101 propionyl-CoA carboxylase beta chain, FASTA score: (75.1% identity in 437 aa overlap). Similar to many other Acetyl/Propionyl CoA Carboxylases from Mycobacterium tuberculosis. Belongs to the AccD / PccB family. (473 aa)
accD5Rv3280, (MTCY71.20, pccB), len: 548 aa. Probable accD5, propionyl-CoA carboxylase beta chain 5, equivalent to P53002|PCCB_MYCLE|ACCD5|ML0731|B1308_C1_125 probable propionyl-CoA carboxylase beta chain 5 from Mycobacterium leprae (549 aa), FASTA scores: opt: 3241, E(): 4e-192,(88.7% identity in 549 aa overlap). Also similar to many e.g. O87201|DTSR2 DTSR2 protein involved in glutamate production from Corynebacterium glutamicum (Brevibacterium flavum) (537 aa), FASTA scores: opt: 2604, E(): 6.9e-153,(74.1% identity in 529 aa overlap) (see Kimura et al.,1996); P53003|PCCB_SACER from Saccha [...] (548 aa)
accE5Rv3281, (MTCY71.21), len: 177 aa. Probable accE5,bifunctional acetyl-/propionyl-coenzyme A carboxylase,epsilon chain, equivalent (but longer 14 aa and with a gap between aa 82-102) to AAK47723|MT3380 from Mycobacterium tuberculosis strain CDC1551 (142 aa), FASTA scores: opt: 830, E(): 3.1e-40, (86.5% identity in 163 aa overlap). C-terminus highly similar to Q49671|B1308_C3_211|ML0730 from Mycobacterium leprae (84 aa), FASTA scores: opt: 393,E(): 7.6e-16, (68.95% identity in 87 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). AccA3 [...] (177 aa)
accA3Rv3285, (MTCY71.25), len: 600 aa. Probable accA3,bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain (see citations below) equivalent to P46392|BCCA_MYCLE|BCCA|ML0726|B1308_C1_129 acetyl-/propionyl-coenzyme A carboxylase alpha chain from Mycobacterium leprae (598 aa), FASTA scores: opt: 3510,E(): 1.1e-196, (89.3% identity in 601 aa overlap). Also highly similar to other proteins e.g. P71122|ACCBC acyl coenzyme A carboxylase from Corynebacterium glutamicum (Brevibacterium flavum) (591 aa), FASTA scores: opt: 2776,E(): 5.6e-154, (71.95% identity in 592 aa overlap); [...] (600 aa)
accD4Rv3799c, (MTV026.04c), len: 522 aa. Probable accD4,propionyl-CoA carboxylase beta chain 4, equivalent to Q9CDB0|ACCD4|ML0102 putative acyl CoA carboxylase from Mycobacterium leprae (517 aa) FASTA scores: opt: 3154, E(): 8e-187, (91.2% identity in 511 aa overlap). Also similar to many e.g. Q9X4K7|PCCB from Streptomyces coelicolor (530 aa), FASTA scores: opt: 1714, E(): 4.4e-98, (50.0% identity in 510 aa overlap); P53003|PCCB_SACER from Saccharopolyspora erythraea (Streptomyces erythraeus) (546 aa), FASTA scores: opt: 1549, E(): 6.6e-88, (50.65% identity in 519 aa overlap); Q9WZH5|TM0716 [...] (522 aa)
accD3Putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; Belongs to the AccD/PCCB family. (495 aa)
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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