(66 nodes) Mixed, incl. Oligosaccharyltransferase complex, and Protein export network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ccdc47.S	Uncharacterized protein. (489 aa)
	Rpn2.S	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (631 aa)
	A0A1L8EP95	Protein kinase domain-containing protein. (355 aa)
	Nomo3.S	Uncharacterized protein. (1231 aa)
	ccdc47	Uncharacterized protein. (488 aa)
	A0A1L8EW42	Protein kinase domain-containing protein. (384 aa)
	nomo3	Uncharacterized protein. (1207 aa)
	A0A1L8F1U4	Uncharacterized protein. (166 aa)
	A0A1L8F2H4	Uncharacterized protein. (400 aa)
	ssr4	Uncharacterized protein. (170 aa)
	Magt1.L	Uncharacterized protein. (329 aa)
	spint2	Uncharacterized protein. (394 aa)
	stt3a	Uncharacterized protein. (705 aa)
	tmem147	Uncharacterized protein. (225 aa)
	Ddost.S	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (448 aa)
	Stt3a.L	Uncharacterized protein. (705 aa)
	tmem147-2	Uncharacterized protein. (251 aa)
	ddost	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (461 aa)
	A0A1L8FQL5	Protein kinase domain-containing protein. (442 aa)
	stt3b	Uncharacterized protein. (820 aa)
	stt3b-2	Uncharacterized protein. (823 aa)
	sec61g	Uncharacterized protein. (68 aa)
	tram2	Translocating chain-associated membrane protein; Belongs to the TRAM family. (371 aa)
	Sec63.L	J domain-containing protein. (737 aa)
	Tram2.L	Translocating chain-associated membrane protein; Belongs to the TRAM family. (371 aa)
	dnajc24	Uncharacterized protein. (145 aa)
	immp1l	Mitochondrial inner membrane protease subunit. (165 aa)
	immp1l-2	Mitochondrial inner membrane protease subunit. (165 aa)
	tmem258	Uncharacterized protein. (79 aa)
	sec61a1	Plug_translocon domain-containing protein. (476 aa)
	Rpn1.L	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (595 aa)
	Spcs2.S	Uncharacterized protein. (194 aa)
	A0A1L8HK26	Uncharacterized protein. (76 aa)
	A0A1L8HL97	Uncharacterized protein. (259 aa)
	spcs3	Signal peptidase complex subunit 3. (180 aa)
	ostc	Oligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (149 aa)
	mlec	Malectin domain-containing protein. (276 aa)
	A0A1L8HRX3	Signal peptidase complex catalytic subunit SEC11. (411 aa)
	ier3ip1	Uncharacterized protein. (82 aa)
	tusc3	Uncharacterized protein. (346 aa)
	ncln	Peptidase_M28 domain-containing protein. (543 aa)
	dad1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (181 aa)
	ier3ip1-2	Uncharacterized protein. (82 aa)
	A0A1L8I2Z1	Signal peptidase complex catalytic subunit SEC11. (177 aa)
	A0A1L8I3H5	Peptidase_M28 domain-containing protein. (539 aa)
	Sec62.S	Uncharacterized protein. (404 aa)
	A0A310U257	Uncharacterized protein. (189 aa)
	Dad1.S	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
	Ostc.L	Oligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (149 aa)
	A0A310U931	Uncharacterized protein. (79 aa)
	krtcap2	LOC100049762 protein. (136 aa)
	tmco1	Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling. (188 aa)
	MGC82823	Signal peptidase complex catalytic subunit SEC11. (179 aa)
	MGC82698	MGC82698 protein. (400 aa)
	ssr1	Ssr1 protein. (291 aa)
	sec63	MGC80164 protein. (755 aa)
	MGC81373	MGC81373 protein. (127 aa)
	spcs3-2	Signal peptidase complex subunit 3. (180 aa)
	wdr83os	MGC81480 protein. (106 aa)
	ssr1-2	MGC64448 protein. (286 aa)
	rpn1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (595 aa)
	sec61a1-2	Sec61a1 protein. (476 aa)
	ssr3	MGC53595 protein. (185 aa)
	sec61b	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
	ost4	p11F3. (37 aa)
	ssr3-2	Translocon-associtaed protein gamma. (185 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EP95	MGC82698	A0A1L8EP95	Q6AZP2	Protein kinase domain-containing protein.	MGC82698 protein.	0.820
A0A1L8EP95	Sec62.S	A0A1L8EP95	A0A310U1L8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.820
A0A1L8EP95	Sec63.L	A0A1L8EP95	A0A1L8G8W1	Protein kinase domain-containing protein.	J domain-containing protein.	0.768
A0A1L8EP95	sec61a1	A0A1L8EP95	A0A1L8GPS0	Protein kinase domain-containing protein.	Plug_translocon domain-containing protein.	0.812
A0A1L8EP95	sec61a1-2	A0A1L8EP95	Q7ZX87	Protein kinase domain-containing protein.	Sec61a1 protein.	0.812
A0A1L8EP95	sec61b	A0A1L8EP95	Q8AVT7	Protein kinase domain-containing protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.821
A0A1L8EP95	sec61g	A0A1L8EP95	A0A1L8FWK5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.946
A0A1L8EP95	sec63	A0A1L8EP95	Q6GQC5	Protein kinase domain-containing protein.	MGC80164 protein.	0.768
A0A1L8EW42	MGC82698	A0A1L8EW42	Q6AZP2	Protein kinase domain-containing protein.	MGC82698 protein.	0.820
A0A1L8EW42	Sec62.S	A0A1L8EW42	A0A310U1L8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.820
A0A1L8EW42	Sec63.L	A0A1L8EW42	A0A1L8G8W1	Protein kinase domain-containing protein.	J domain-containing protein.	0.768
A0A1L8EW42	sec61a1	A0A1L8EW42	A0A1L8GPS0	Protein kinase domain-containing protein.	Plug_translocon domain-containing protein.	0.812
A0A1L8EW42	sec61a1-2	A0A1L8EW42	Q7ZX87	Protein kinase domain-containing protein.	Sec61a1 protein.	0.812
A0A1L8EW42	sec61b	A0A1L8EW42	Q8AVT7	Protein kinase domain-containing protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.821
A0A1L8EW42	sec61g	A0A1L8EW42	A0A1L8FWK5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.946
A0A1L8EW42	sec63	A0A1L8EW42	Q6GQC5	Protein kinase domain-containing protein.	MGC80164 protein.	0.768
A0A1L8F1U4	A0A1L8HK26	A0A1L8F1U4	A0A1L8HK26	Uncharacterized protein.	Uncharacterized protein.	0.508
A0A1L8F1U4	A0A310U931	A0A1L8F1U4	A0A310U931	Uncharacterized protein.	Uncharacterized protein.	0.670
A0A1L8F1U4	Dad1.S	A0A1L8F1U4	A0A310U366	Uncharacterized protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.722
A0A1L8F1U4	Ddost.S	A0A1L8F1U4	A0A1L8FHR0	Uncharacterized protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	0.829