(47 nodes) Mixed, incl. Rho (Ras homology) subfamily of Ras-like small GTPases, and Rho Binding network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8ENM9	Uncharacterized protein. (2737 aa)
	Rhoa.S	Uncharacterized protein. (216 aa)
	rhogl.1	Uncharacterized protein. (191 aa)
	Rhov.S	Uncharacterized protein. (92 aa)
	A0A1L8F6Z7	FH2 domain-containing protein. (1371 aa)
	Diaph2.L	Uncharacterized protein. (497 aa)
	A0A1L8F7H9	FH2 domain-containing protein. (108 aa)
	A0A1L8FAA5	Uncharacterized protein. (1077 aa)
	A0A1L8FB22	Uncharacterized protein. (240 aa)
	iqgap3	Uncharacterized protein. (1641 aa)
	Rock1.S	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1367 aa)
	A0A1L8FWY8	PH domain-containing protein. (985 aa)
	Trio.L	Uncharacterized protein. (1879 aa)
	Rock1.L	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1360 aa)
	A0A1L8G0W2	Uncharacterized protein. (1082 aa)
	rock2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1399 aa)
	Rock2.L	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1373 aa)
	Arhgap1.S	Uncharacterized protein. (473 aa)
	A0A1L8GHD2	Uncharacterized protein. (193 aa)
	Arhgap1.L	Uncharacterized protein. (435 aa)
	A0A1L8GLK0	PH domain-containing protein. (864 aa)
	A0A1L8GNY3	Uncharacterized protein. (207 aa)
	A0A1L8GTB8	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2543 aa)
	Diaph1.S	Uncharacterized protein. (1144 aa)
	diaph1	Uncharacterized protein. (1272 aa)
	Myosin-9a	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2578 aa)
	rhobtb2	Uncharacterized protein. (786 aa)
	A0A1L8H6N1	Uncharacterized protein. (193 aa)
	A0A1L8HBM5	FH2 domain-containing protein. (707 aa)
	abr	Uncharacterized protein. (1018 aa)
	rhoh	Uncharacterized protein. (191 aa)
	Cit.S	Uncharacterized protein. (1714 aa)
	Rhof.S	Uncharacterized protein. (245 aa)
	A0A1L8HRI8	Uncharacterized protein. (1601 aa)
	rhoh-2	Uncharacterized protein. (190 aa)
	Myo9b.L	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2143 aa)
	cit	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2068 aa)
	Rhof.L	Uncharacterized protein. (266 aa)
	A0A1L8I203	Uncharacterized protein. (1661 aa)
	rhob	MGC131029 protein. (196 aa)
	pfn1	Profilin; Belongs to the profilin family. (138 aa)
	arhgdib	LOC496152 protein. (200 aa)
	rhobtb1-2	MGC80424 protein. (691 aa)
	arhgdia	Arhgdia protein. (204 aa)
	arhgdig	MGC69119 protein. (199 aa)
	arhgdib-2	Arhgdib-prov protein. (200 aa)
	myl12b	Cytoplasmic myosin II regulatory light chain. (172 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ENM9	A0A1L8FB22	A0A1L8ENM9	A0A1L8FB22	Uncharacterized protein.	Uncharacterized protein.	0.655
A0A1L8ENM9	A0A1L8GHD2	A0A1L8ENM9	A0A1L8GHD2	Uncharacterized protein.	Uncharacterized protein.	0.657
A0A1L8ENM9	A0A1L8GNY3	A0A1L8ENM9	A0A1L8GNY3	Uncharacterized protein.	Uncharacterized protein.	0.710
A0A1L8ENM9	A0A1L8H6N1	A0A1L8ENM9	A0A1L8H6N1	Uncharacterized protein.	Uncharacterized protein.	0.657
A0A1L8ENM9	Rhoa.S	A0A1L8ENM9	A0A1L8EZK4	Uncharacterized protein.	Uncharacterized protein.	0.657
A0A1L8ENM9	Rhof.L	A0A1L8ENM9	A0A1L8I1B0	Uncharacterized protein.	Uncharacterized protein.	0.691
A0A1L8ENM9	Rhof.S	A0A1L8ENM9	A0A1L8HQP4	Uncharacterized protein.	Uncharacterized protein.	0.691
A0A1L8ENM9	Rhov.S	A0A1L8ENM9	A0A1L8F4A8	Uncharacterized protein.	Uncharacterized protein.	0.708
A0A1L8ENM9	myl12b	A0A1L8ENM9	Q91625	Uncharacterized protein.	Cytoplasmic myosin II regulatory light chain.	0.476
A0A1L8ENM9	rhob	A0A1L8ENM9	Q2TAR5	Uncharacterized protein.	MGC131029 protein.	0.657
A0A1L8ENM9	rhobtb1-2	A0A1L8ENM9	Q6GPF1	Uncharacterized protein.	MGC80424 protein.	0.702
A0A1L8ENM9	rhobtb2	A0A1L8ENM9	A0A1L8H237	Uncharacterized protein.	Uncharacterized protein.	0.709
A0A1L8ENM9	rhogl.1	A0A1L8ENM9	A0A1L8F2C9	Uncharacterized protein.	Uncharacterized protein.	0.655
A0A1L8ENM9	rhoh	A0A1L8ENM9	A0A1L8HL18	Uncharacterized protein.	Uncharacterized protein.	0.652
A0A1L8ENM9	rhoh-2	A0A1L8ENM9	A0A1L8HTK9	Uncharacterized protein.	Uncharacterized protein.	0.652
A0A1L8F6Z7	A0A1L8F7H9	A0A1L8F6Z7	A0A1L8F7H9	FH2 domain-containing protein.	FH2 domain-containing protein.	0.466
A0A1L8F6Z7	A0A1L8FB22	A0A1L8F6Z7	A0A1L8FB22	FH2 domain-containing protein.	Uncharacterized protein.	0.424
A0A1L8F6Z7	A0A1L8FWY8	A0A1L8F6Z7	A0A1L8FWY8	FH2 domain-containing protein.	PH domain-containing protein.	0.523
A0A1L8F6Z7	A0A1L8GHD2	A0A1L8F6Z7	A0A1L8GHD2	FH2 domain-containing protein.	Uncharacterized protein.	0.527
A0A1L8F6Z7	A0A1L8GLK0	A0A1L8F6Z7	A0A1L8GLK0	FH2 domain-containing protein.	PH domain-containing protein.	0.523