84 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8EKP1	Receptor protein-tyrosine kinase. (1290 aa)
	ptpn1	Tyrosine-protein phosphatase non-receptor type. (430 aa)
	Sla2.S	Uncharacterized protein. (266 aa)
	grb2	Uncharacterized protein. (229 aa)
	A0A1L8EPK3	Receptor protein-tyrosine kinase. (1256 aa)
	grap	Uncharacterized protein. (219 aa)
	hck	Tyrosine-protein kinase. (496 aa)
	erbb2	Receptor protein-tyrosine kinase. (1299 aa)
	grb2-2	Uncharacterized protein. (229 aa)
	A0A1L8EWP4	Receptor protein-tyrosine kinase. (1083 aa)
	grap-2	Uncharacterized protein. (219 aa)
	sos2	Uncharacterized protein. (1335 aa)
	Irs4.S	Uncharacterized protein. (1088 aa)
	insrr	Tyrosine-protein kinase receptor. (1359 aa)
	shc1	Uncharacterized protein. (605 aa)
	irs4	Uncharacterized protein. (1077 aa)
	sos2-2	Uncharacterized protein. (1332 aa)
	Insrr.L	Tyrosine-protein kinase receptor. (1358 aa)
	Shc1.L	Uncharacterized protein. (601 aa)
	ptpn6	Uncharacterized protein. (687 aa)
	A0A1L8FG16	Uncharacterized protein. (559 aa)
	A0A1L8FGY8	Uncharacterized protein. (493 aa)
	A0A1L8FN82	Uncharacterized protein. (507 aa)
	A0A1L8FNC2	Uncharacterized protein. (198 aa)
	A0A1L8FND1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
	grb10	Uncharacterized protein. (535 aa)
	grb10-2	Uncharacterized protein. (591 aa)
	sos1	Uncharacterized protein. (1325 aa)
	A0A1L8G3Z7	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	A0A1L8G4J8	Uncharacterized protein. (1123 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	sos1-2	Uncharacterized protein. (1325 aa)
	fyn	Tyrosine-protein kinase. (537 aa)
	A0A1L8GA65	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1009 aa)
	Irs1.S	Uncharacterized protein. (1227 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	A0A1L8GBL7	Uncharacterized protein. (589 aa)
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	Frs2.S	IRS-type PTB domain-containing protein. (509 aa)
	spry4	Uncharacterized protein. (297 aa)
	frs2	IRS-type PTB domain-containing protein. (518 aa)
	shc4	Uncharacterized protein. (568 aa)
	igf1r	Tyrosine-protein kinase receptor. (1358 aa)
	A0A1L8H482	Uncharacterized protein. (814 aa)
	sh2b2	Uncharacterized protein. (661 aa)
	sh3d21	Uncharacterized protein. (556 aa)
	Cblb.S	Uncharacterized protein. (979 aa)
	A0A1L8H929	Uncharacterized protein. (1008 aa)
	erbb3	Protein kinase domain-containing protein. (1331 aa)
	gab2	PH domain-containing protein. (673 aa)
	sh2b2-2	Uncharacterized protein. (665 aa)
	Cblb.L	Uncharacterized protein. (978 aa)
	A0A1L8HH28	Uncharacterized protein. (1011 aa)
	erbb3-2	Protein kinase domain-containing protein. (1347 aa)
	gab2-2	PH domain-containing protein. (677 aa)
	A0A1L8HNI8	Uncharacterized protein. (721 aa)
	shc2	Uncharacterized protein. (624 aa)
	A0A1L8HPF0	Uncharacterized protein. (629 aa)
	A0A1L8HTZ2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
	A0A1L8HW99	Uncharacterized protein. (576 aa)
	A0A1L8HWT4	Uncharacterized protein. (717 aa)
	shc2-2	Uncharacterized protein. (624 aa)
	A0A1L8HZ53	Uncharacterized protein. (628 aa)
	A0A1L8I158	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
	Gab1.L	PH domain-containing protein. (682 aa)
	Cbl.S	Uncharacterized protein. (945 aa)
	ins-2	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	PIK3R1	Phosphoinositide-3-kinase. (722 aa)
	fyn-2	Tyrosine-protein kinase. (537 aa)
	LOC398006	Tyrosine-protein kinase receptor. (1362 aa)
	LOC398022	Tyrosine-protein kinase receptor. (1363 aa)
	ptpn6-2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (587 aa)
	rabif	MGC115104 protein. (118 aa)
	pik3r3	MGC84470 protein. (461 aa)
	gab1	MGC81548 protein. (691 aa)
	pik3r2	Pik3r2-prov protein. (457 aa)
	ptpn1-2	Tyrosine-protein phosphatase non-receptor type. (428 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	pik3r1	MGC80357 protein. (722 aa)
	frs3	Frs3 protein. (517 aa)
	vav2-2	MGC68892 protein. (832 aa)
	yes1	Tyrosine-protein kinase. (537 aa)
	hras	Small G-protein H-Ras. (189 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKP1	A0A1L8EPK3	A0A1L8EKP1	A0A1L8EPK3	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.803
A0A1L8EKP1	A0A1L8FG16	A0A1L8EKP1	A0A1L8FG16	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.561
A0A1L8EKP1	A0A1L8FGY8	A0A1L8EKP1	A0A1L8FGY8	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.720
A0A1L8EKP1	A0A1L8FN82	A0A1L8EKP1	A0A1L8FN82	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.720
A0A1L8EKP1	A0A1L8FND1	A0A1L8EKP1	A0A1L8FND1	Receptor protein-tyrosine kinase.	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.723
A0A1L8EKP1	A0A1L8G3Z7	A0A1L8EKP1	A0A1L8G3Z7	Receptor protein-tyrosine kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.838
A0A1L8EKP1	A0A1L8GA65	A0A1L8EKP1	A0A1L8GA65	Receptor protein-tyrosine kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.557
A0A1L8EKP1	A0A1L8GBL7	A0A1L8EKP1	A0A1L8GBL7	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.441
A0A1L8EKP1	A0A1L8HNI8	A0A1L8EKP1	A0A1L8HNI8	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.821
A0A1L8EKP1	A0A1L8HPF0	A0A1L8EKP1	A0A1L8HPF0	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.894
A0A1L8EKP1	A0A1L8HW99	A0A1L8EKP1	A0A1L8HW99	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.706
A0A1L8EKP1	A0A1L8HWT4	A0A1L8EKP1	A0A1L8HWT4	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.821
A0A1L8EKP1	A0A1L8HZ53	A0A1L8EKP1	A0A1L8HZ53	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.894
A0A1L8EKP1	A0A1L8I158	A0A1L8EKP1	A0A1L8I158	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.561
A0A1L8EKP1	Cbl.S	A0A1L8EKP1	A0A310TNL8	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.720
A0A1L8EKP1	Cblb.L	A0A1L8EKP1	A0A1L8HGE9	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.720
A0A1L8EKP1	Cblb.S	A0A1L8EKP1	A0A1L8H8G5	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.720
A0A1L8EKP1	Gab1.L	A0A1L8EKP1	A0A310TNH6	Receptor protein-tyrosine kinase.	PH domain-containing protein.	0.655
A0A1L8EKP1	PIK3R1	A0A1L8EKP1	B7ZRD8	Receptor protein-tyrosine kinase.	Phosphoinositide-3-kinase.	0.821
A0A1L8EKP1	Ptpn11.S	A0A1L8EKP1	Q92124	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.561