(14 nodes) BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members, and Apoptosis regulator, Bcl-2, BH1 motif, conserved site network (Xenopus laevis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	A0A1L8ELY1	BH4_2 domain-containing protein. (219 aa)
	A0A1L8ETC2	BH4_2 domain-containing protein. (212 aa)
	mcl1	Uncharacterized protein. (277 aa)
	bmf	Uncharacterized protein. (183 aa)
	Mcl1.L	Uncharacterized protein. (277 aa)
	Bax.L	Uncharacterized protein. (221 aa)
	Bcl2.S	BH4_2 domain-containing protein. (253 aa)
	A0A1L8FW52	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	A0A1L8FXP7	BH4_2 domain-containing protein. (300 aa)
	bcl2l11	Uncharacterized protein. (194 aa)
	bcl2l11-2	Uncharacterized protein. (194 aa)
	A0A1L8GJQ1	Uncharacterized protein. (151 aa)
	Bid.S	Uncharacterized protein. (238 aa)
	bcl2l2	MGC80617 protein. (188 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ELY1	A0A1L8FW52	A0A1L8ELY1	A0A1L8FW52	BH4_2 domain-containing protein.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.651
A0A1L8ELY1	A0A1L8FXP7	A0A1L8ELY1	A0A1L8FXP7	BH4_2 domain-containing protein.	BH4_2 domain-containing protein.	0.881
A0A1L8ELY1	A0A1L8GJQ1	A0A1L8ELY1	A0A1L8GJQ1	BH4_2 domain-containing protein.	Uncharacterized protein.	0.977
A0A1L8ELY1	Bax.L	A0A1L8ELY1	A0A1L8FH04	BH4_2 domain-containing protein.	Uncharacterized protein.	0.978
A0A1L8ELY1	Bcl2.S	A0A1L8ELY1	A0A1L8FSA4	BH4_2 domain-containing protein.	BH4_2 domain-containing protein.	0.885
A0A1L8ELY1	Bid.S	A0A1L8ELY1	A0A1L8GQT1	BH4_2 domain-containing protein.	Uncharacterized protein.	0.976
A0A1L8ELY1	Mcl1.L	A0A1L8ELY1	A0A1L8FBT2	BH4_2 domain-containing protein.	Uncharacterized protein.	0.430
A0A1L8ELY1	bcl2l11	A0A1L8ELY1	A0A1L8G1Y7	BH4_2 domain-containing protein.	Uncharacterized protein.	0.971
A0A1L8ELY1	bcl2l11-2	A0A1L8ELY1	A0A1L8G7D9	BH4_2 domain-containing protein.	Uncharacterized protein.	0.971
A0A1L8ELY1	bmf	A0A1L8ELY1	A0A1L8FAY6	BH4_2 domain-containing protein.	Uncharacterized protein.	0.703
A0A1L8ELY1	mcl1	A0A1L8ELY1	A0A1L8F4J2	BH4_2 domain-containing protein.	Uncharacterized protein.	0.430
A0A1L8ETC2	A0A1L8FW52	A0A1L8ETC2	A0A1L8FW52	BH4_2 domain-containing protein.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.651
A0A1L8ETC2	A0A1L8FXP7	A0A1L8ETC2	A0A1L8FXP7	BH4_2 domain-containing protein.	BH4_2 domain-containing protein.	0.975
A0A1L8ETC2	A0A1L8GJQ1	A0A1L8ETC2	A0A1L8GJQ1	BH4_2 domain-containing protein.	Uncharacterized protein.	0.997
A0A1L8ETC2	Bax.L	A0A1L8ETC2	A0A1L8FH04	BH4_2 domain-containing protein.	Uncharacterized protein.	0.997
A0A1L8ETC2	Bcl2.S	A0A1L8ETC2	A0A1L8FSA4	BH4_2 domain-containing protein.	BH4_2 domain-containing protein.	0.975
A0A1L8ETC2	Bid.S	A0A1L8ETC2	A0A1L8GQT1	BH4_2 domain-containing protein.	Uncharacterized protein.	0.976
A0A1L8ETC2	Mcl1.L	A0A1L8ETC2	A0A1L8FBT2	BH4_2 domain-containing protein.	Uncharacterized protein.	0.430
A0A1L8ETC2	bcl2l11	A0A1L8ETC2	A0A1L8G1Y7	BH4_2 domain-containing protein.	Uncharacterized protein.	0.997
A0A1L8ETC2	bcl2l11-2	A0A1L8ETC2	A0A1L8G7D9	BH4_2 domain-containing protein.	Uncharacterized protein.	0.997