(14 nodes) Mixed, incl. Sox developmental protein N terminal , and Embryonic nail plate morphogenesis network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	twist1	BHLH domain-containing protein. (166 aa)
	tfap2a	TF_AP-2 domain-containing protein. (470 aa)
	Tfap2a.L	TF_AP-2 domain-containing protein. (472 aa)
	snai2	Uncharacterized protein. (266 aa)
	Zic1.S	Uncharacterized protein. (443 aa)
	Pax3.S	Uncharacterized protein. (592 aa)
	Pax3.L	Uncharacterized protein. (590 aa)
	sox10	HMG box domain-containing protein. (438 aa)
	sox10-2	HMG box domain-containing protein. (446 aa)
	msx1	Homeobox domain-containing protein. (275 aa)
	msx1-2	LOC100125666 protein. (273 aa)
	zic5-2	Zic family member 5. (515 aa)
	sox9-a	Sex determining region Y-box 9. (477 aa)
	snai2-2	Zinc finger transcription factor slug beta. (266 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Pax3.L	Tfap2a.L	A0A1L8GAS7	A0A1L8FXY3	Uncharacterized protein.	TF_AP-2 domain-containing protein.	0.799
Pax3.L	Zic1.S	A0A1L8GAS7	A0A1L8G4L5	Uncharacterized protein.	Uncharacterized protein.	0.889
Pax3.L	msx1	A0A1L8GAS7	A0A1L8HKV3	Uncharacterized protein.	Homeobox domain-containing protein.	0.424
Pax3.L	msx1-2	A0A1L8GAS7	A5D8L7	Uncharacterized protein.	LOC100125666 protein.	0.429
Pax3.L	snai2	A0A1L8GAS7	A0A1L8FYY4	Uncharacterized protein.	Uncharacterized protein.	0.896
Pax3.L	snai2-2	A0A1L8GAS7	Q90VW5	Uncharacterized protein.	Zinc finger transcription factor slug beta.	0.896
Pax3.L	sox10	A0A1L8GAS7	A0A1L8GH44	Uncharacterized protein.	HMG box domain-containing protein.	0.909
Pax3.L	sox10-2	A0A1L8GAS7	A0A1L8GNW7	Uncharacterized protein.	HMG box domain-containing protein.	0.909
Pax3.L	sox9-a	A0A1L8GAS7	I3QHH4	Uncharacterized protein.	Sex determining region Y-box 9.	0.836
Pax3.L	tfap2a	A0A1L8GAS7	A0A1L8FS35	Uncharacterized protein.	TF_AP-2 domain-containing protein.	0.799
Pax3.L	twist1	A0A1L8GAS7	A0A1L8FR58	Uncharacterized protein.	BHLH domain-containing protein.	0.585
Pax3.L	zic5-2	A0A1L8GAS7	B7ZPU8	Uncharacterized protein.	Zic family member 5.	0.889
Pax3.S	Tfap2a.L	A0A1L8G4P8	A0A1L8FXY3	Uncharacterized protein.	TF_AP-2 domain-containing protein.	0.799
Pax3.S	Zic1.S	A0A1L8G4P8	A0A1L8G4L5	Uncharacterized protein.	Uncharacterized protein.	0.889
Pax3.S	msx1	A0A1L8G4P8	A0A1L8HKV3	Uncharacterized protein.	Homeobox domain-containing protein.	0.424
Pax3.S	msx1-2	A0A1L8G4P8	A5D8L7	Uncharacterized protein.	LOC100125666 protein.	0.425
Pax3.S	snai2	A0A1L8G4P8	A0A1L8FYY4	Uncharacterized protein.	Uncharacterized protein.	0.896
Pax3.S	snai2-2	A0A1L8G4P8	Q90VW5	Uncharacterized protein.	Zinc finger transcription factor slug beta.	0.896
Pax3.S	sox10	A0A1L8G4P8	A0A1L8GH44	Uncharacterized protein.	HMG box domain-containing protein.	0.909
Pax3.S	sox10-2	A0A1L8G4P8	A0A1L8GNW7	Uncharacterized protein.	HMG box domain-containing protein.	0.909