(7 nodes) Mixed, incl. Neural crest cell fate specification, and Transcription factor, Brachyury network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sia1.L	Siamois homeodomain 1.L. (246 aa)
	Gsc.S	Homeobox domain-containing protein. (243 aa)
	gsc	Homeobox domain-containing protein. (294 aa)
	tbxt	Uncharacterized protein. (432 aa)
	foxa4	Fork-head domain-containing protein. (399 aa)
	not	Homeobox domain-containing protein. (233 aa)
	tbxt-2	MGC81453 protein. (432 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gsc.S	foxa4	A0A1L8F0K5	A0A1L8GJZ0	Homeobox domain-containing protein.	Fork-head domain-containing protein.	0.643
Gsc.S	sia1.L	A0A1L8F0K5	A0A1B4ZDM4	Homeobox domain-containing protein.	Siamois homeodomain 1.L.	0.889
Gsc.S	tbxt	A0A1L8F0K5	A0A1L8G2B1	Homeobox domain-containing protein.	Uncharacterized protein.	0.945
Gsc.S	tbxt-2	A0A1L8F0K5	Q6INQ0	Homeobox domain-containing protein.	MGC81453 protein.	0.946
foxa4	Gsc.S	A0A1L8GJZ0	A0A1L8F0K5	Fork-head domain-containing protein.	Homeobox domain-containing protein.	0.643
foxa4	gsc	A0A1L8GJZ0	A0A1L8F9K8	Fork-head domain-containing protein.	Homeobox domain-containing protein.	0.689
foxa4	not	A0A1L8GJZ0	A0A1L8HSR3	Fork-head domain-containing protein.	Homeobox domain-containing protein.	0.661
foxa4	sia1.L	A0A1L8GJZ0	A0A1B4ZDM4	Fork-head domain-containing protein.	Siamois homeodomain 1.L.	0.460
foxa4	tbxt	A0A1L8GJZ0	A0A1L8G2B1	Fork-head domain-containing protein.	Uncharacterized protein.	0.744
foxa4	tbxt-2	A0A1L8GJZ0	Q6INQ0	Fork-head domain-containing protein.	MGC81453 protein.	0.744
gsc	foxa4	A0A1L8F9K8	A0A1L8GJZ0	Homeobox domain-containing protein.	Fork-head domain-containing protein.	0.689
gsc	sia1.L	A0A1L8F9K8	A0A1B4ZDM4	Homeobox domain-containing protein.	Siamois homeodomain 1.L.	0.889
gsc	tbxt	A0A1L8F9K8	A0A1L8G2B1	Homeobox domain-containing protein.	Uncharacterized protein.	0.945
gsc	tbxt-2	A0A1L8F9K8	Q6INQ0	Homeobox domain-containing protein.	MGC81453 protein.	0.945
not	foxa4	A0A1L8HSR3	A0A1L8GJZ0	Homeobox domain-containing protein.	Fork-head domain-containing protein.	0.661
not	sia1.L	A0A1L8HSR3	A0A1B4ZDM4	Homeobox domain-containing protein.	Siamois homeodomain 1.L.	0.495
not	tbxt	A0A1L8HSR3	A0A1L8G2B1	Homeobox domain-containing protein.	Uncharacterized protein.	0.879
not	tbxt-2	A0A1L8HSR3	Q6INQ0	Homeobox domain-containing protein.	MGC81453 protein.	0.879
sia1.L	Gsc.S	A0A1B4ZDM4	A0A1L8F0K5	Siamois homeodomain 1.L.	Homeobox domain-containing protein.	0.889
sia1.L	foxa4	A0A1B4ZDM4	A0A1L8GJZ0	Siamois homeodomain 1.L.	Fork-head domain-containing protein.	0.460