(8 nodes) Notch signaling involved in heart development, and LAG1, DNA binding network (Xenopus laevis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	Notch1.S	Uncharacterized protein. (2524 aa)
	notch1	Uncharacterized protein. (2521 aa)
	jag1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1206 aa)
	Jag1.L	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
	maml2	MamL-1 domain-containing protein. (994 aa)
	Rbpj.S	Uncharacterized protein. (485 aa)
	rbpj	Uncharacterized protein. (487 aa)
	XMam1	XMam1 protein. (1039 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Jag1.L	Notch1.S	A0A1L8G723	A0A1L8F124	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.996
Jag1.L	Rbpj.S	A0A1L8G723	A0A1L8HL49	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.934
Jag1.L	XMam1	A0A1L8G723	B7ZQH4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	XMam1 protein.	0.835
Jag1.L	jag1	A0A1L8G723	A0A1L8G0P5	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.900
Jag1.L	maml2	A0A1L8G723	A0A1L8HAW0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	MamL-1 domain-containing protein.	0.793
Jag1.L	notch1	A0A1L8G723	A0A1L8F627	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.996
Jag1.L	rbpj	A0A1L8G723	A0A1L8HTS9	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.934
Notch1.S	Jag1.L	A0A1L8F124	A0A1L8G723	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.996
Notch1.S	Rbpj.S	A0A1L8F124	A0A1L8HL49	Uncharacterized protein.	Uncharacterized protein.	0.999
Notch1.S	XMam1	A0A1L8F124	B7ZQH4	Uncharacterized protein.	XMam1 protein.	0.992
Notch1.S	jag1	A0A1L8F124	A0A1L8G0P5	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.996
Notch1.S	maml2	A0A1L8F124	A0A1L8HAW0	Uncharacterized protein.	MamL-1 domain-containing protein.	0.944
Notch1.S	rbpj	A0A1L8F124	A0A1L8HTS9	Uncharacterized protein.	Uncharacterized protein.	0.999
Rbpj.S	Jag1.L	A0A1L8HL49	A0A1L8G723	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.934
Rbpj.S	Notch1.S	A0A1L8HL49	A0A1L8F124	Uncharacterized protein.	Uncharacterized protein.	0.999
Rbpj.S	XMam1	A0A1L8HL49	B7ZQH4	Uncharacterized protein.	XMam1 protein.	0.999
Rbpj.S	jag1	A0A1L8HL49	A0A1L8G0P5	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.934
Rbpj.S	maml2	A0A1L8HL49	A0A1L8HAW0	Uncharacterized protein.	MamL-1 domain-containing protein.	0.999
Rbpj.S	notch1	A0A1L8HL49	A0A1L8F627	Uncharacterized protein.	Uncharacterized protein.	0.999
Rbpj.S	rbpj	A0A1L8HL49	A0A1L8HTS9	Uncharacterized protein.	Uncharacterized protein.	0.965