STRINGSTRING
Dkk3.S Dkk3.S Lrp5.L Lrp5.L wif1 wif1 Kremen1.S Kremen1.S wif1-2 wif1-2 dkk1-2 dkk1-2 dkk2-2 dkk2-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Dkk3.SDickkopf_N domain-containing protein. (257 aa)
Lrp5.LUncharacterized protein. (1517 aa)
wif1Uncharacterized protein. (374 aa)
Kremen1.SKremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (452 aa)
wif1-2Wnt inhibitory factor-1. (374 aa)
dkk1-2Dickkopf homolog 1. (259 aa)
dkk2-2Dickkopf homolog 2. (255 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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