(58 nodes) Basic region leucin zipper, and KIX domain network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A0U2V4Z5	FosB-like protein. (296 aa)
	Cebpb.S	CCAAT/enhancer-binding protein. (288 aa)
	crebbp	Uncharacterized protein. (2424 aa)
	nfatc2	RHD domain-containing protein. (896 aa)
	Cebpb.L	CCAAT/enhancer-binding protein. (281 aa)
	crebbp-2	Uncharacterized protein. (2453 aa)
	foxa1	Fork-head domain-containing protein. (427 aa)
	Batf.S	BZIP domain-containing protein. (115 aa)
	Usf1.S	BHLH domain-containing protein. (333 aa)
	A0A1L8F856	BZIP domain-containing protein. (296 aa)
	esr2	Uncharacterized protein. (548 aa)
	foxa1-2	Fork-head domain-containing protein. (429 aa)
	A0A1L8FDL6	Uncharacterized protein. (155 aa)
	Cdca7l.L	Uncharacterized protein. (347 aa)
	Creb5.S	Uncharacterized protein. (496 aa)
	creb5	Uncharacterized protein. (501 aa)
	fosl2	BZIP domain-containing protein. (316 aa)
	atf3	BZIP domain-containing protein. (182 aa)
	Esr1.S	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
	Myb.S	Uncharacterized protein. (626 aa)
	A0A1L8G6K7	BZIP domain-containing protein. (346 aa)
	trib2	Protein kinase domain-containing protein. (343 aa)
	fosl1	BZIP domain-containing protein. (261 aa)
	A0A1L8GGQ9	BZIP domain-containing protein. (137 aa)
	ep300	Uncharacterized protein. (2495 aa)
	Atf4.S	BZIP domain-containing protein. (342 aa)
	fosl1-2	BZIP domain-containing protein. (306 aa)
	Men1.L	Uncharacterized protein. (675 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	ep300-2	Uncharacterized protein. (2492 aa)
	Atf4.L	BZIP domain-containing protein. (343 aa)
	egr1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (497 aa)
	Junb.L	BZIP domain-containing protein. (306 aa)
	nrip1	Uncharacterized protein. (1135 aa)
	ddit3	Uncharacterized protein. (207 aa)
	atf7	Uncharacterized protein. (468 aa)
	sp1	Uncharacterized protein. (732 aa)
	znf740	Uncharacterized protein. (215 aa)
	PR-2	Uncharacterized protein. (730 aa)
	A0A1L8HIH1	BZIP domain-containing protein. (534 aa)
	znf740-2	Uncharacterized protein. (218 aa)
	sp1-2	Uncharacterized protein. (722 aa)
	Jund.S	BZIP domain-containing protein. (300 aa)
	jund	BZIP domain-containing protein. (300 aa)
	A0A1L8HYA8	BZIP domain-containing protein. (436 aa)
	fos	BZIP domain-containing protein. (369 aa)
	gata3	XGATA-3 protein. (435 aa)
	usf2	LOC494839 protein. (310 aa)
	atf3-2	MGC81814 protein. (181 aa)
	fos-2	MGC80305 protein. (368 aa)
	atf5.2	Atf5-prov protein. (308 aa)
	tle2	ESG protein. (768 aa)
	esr1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
	ddit3-2	Transcription factor GADD153. (211 aa)
	creb1	Creb1-prov protein. (324 aa)
	cebpa	CCAAT/enhancer-binding protein. (305 aa)
	pgr	Progesterone receptor. (732 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0U2V4Z5	A0A1L8G6K7	A0A0U2V4Z5	A0A1L8G6K7	FosB-like protein.	BZIP domain-containing protein.	0.719
A0A0U2V4Z5	A0A1L8HYA8	A0A0U2V4Z5	A0A1L8HYA8	FosB-like protein.	BZIP domain-containing protein.	0.924
A0A0U2V4Z5	Jun.L	A0A0U2V4Z5	A0A1L8GLZ4	FosB-like protein.	BZIP domain-containing protein; Belongs to the bZIP family.	0.924
A0A0U2V4Z5	Junb.L	A0A0U2V4Z5	A0A1L8H2X9	FosB-like protein.	BZIP domain-containing protein.	0.884
A0A0U2V4Z5	Jund.S	A0A0U2V4Z5	A0A1L8HNI0	FosB-like protein.	BZIP domain-containing protein.	0.947
A0A0U2V4Z5	atf3	A0A0U2V4Z5	A0A1L8G1E5	FosB-like protein.	BZIP domain-containing protein.	0.553
A0A0U2V4Z5	atf3-2	A0A0U2V4Z5	Q68F43	FosB-like protein.	MGC81814 protein.	0.553
A0A0U2V4Z5	c-Jun	A0A0U2V4Z5	Q9PVZ1	FosB-like protein.	C-Jun protein; Belongs to the bZIP family.	0.924
A0A0U2V4Z5	creb1	A0A0U2V4Z5	Q8AVY5	FosB-like protein.	Creb1-prov protein.	0.443
A0A0U2V4Z5	egr1	A0A0U2V4Z5	A0A1L8GY02	FosB-like protein.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.484
A0A0U2V4Z5	fos	A0A0U2V4Z5	A9UMM6	FosB-like protein.	BZIP domain-containing protein.	0.879
A0A0U2V4Z5	fos-2	A0A0U2V4Z5	Q6AXA4	FosB-like protein.	MGC80305 protein.	0.880
A0A0U2V4Z5	fosl1	A0A0U2V4Z5	A0A1L8GD58	FosB-like protein.	BZIP domain-containing protein.	0.575
A0A0U2V4Z5	fosl1-2	A0A0U2V4Z5	A0A1L8GJV9	FosB-like protein.	BZIP domain-containing protein.	0.591
A0A0U2V4Z5	fosl2	A0A0U2V4Z5	A0A1L8G121	FosB-like protein.	BZIP domain-containing protein.	0.711
A0A0U2V4Z5	jund	A0A0U2V4Z5	A0A1L8HWV5	FosB-like protein.	BZIP domain-containing protein.	0.947
A0A1L8F856	A0A1L8G6K7	A0A1L8F856	A0A1L8G6K7	BZIP domain-containing protein.	BZIP domain-containing protein.	0.718
A0A1L8F856	A0A1L8HYA8	A0A1L8F856	A0A1L8HYA8	BZIP domain-containing protein.	BZIP domain-containing protein.	0.924
A0A1L8F856	Jun.L	A0A1L8F856	A0A1L8GLZ4	BZIP domain-containing protein.	BZIP domain-containing protein; Belongs to the bZIP family.	0.924
A0A1L8F856	Junb.L	A0A1L8F856	A0A1L8H2X9	BZIP domain-containing protein.	BZIP domain-containing protein.	0.884