102 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Smo.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
	pthlh	Uncharacterized protein. (169 aa)
	myoc	Olfactomedin-like domain-containing protein. (515 aa)
	tnn	Uncharacterized protein. (1091 aa)
	A0A1L8GLM2	Uncharacterized protein. (375 aa)
	A0A1L8GKT4	Uncharacterized protein. (194 aa)
	A0A1L8GKT2	Uncharacterized protein. (160 aa)
	cbfb-2	Uncharacterized protein. (185 aa)
	Men1.L	Uncharacterized protein. (675 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	igf2-2	IlGF domain-containing protein. (217 aa)
	lgr4	G_PROTEIN_RECEP_F1_2 domain-containing protein. (953 aa)
	creb3l1	BZIP domain-containing protein. (474 aa)
	Myoc.S	Olfactomedin-like domain-containing protein. (507 aa)
	A0A1L8GF46	Uncharacterized protein. (343 aa)
	A0A1L8GEH0	Uncharacterized protein. (193 aa)
	cbfb	Uncharacterized protein. (185 aa)
	A0A1L8GE31	BZIP domain-containing protein. (418 aa)
	Lgr4.S	G_PROTEIN_RECEP_F1_2 domain-containing protein. (956 aa)
	igf2	IlGF domain-containing protein. (217 aa)
	ift80	WD_REPEATS_REGION domain-containing protein. (779 aa)
	asf1a	Uncharacterized protein. (201 aa)
	Bmp2.L	TGF_BETA_2 domain-containing protein. (398 aa)
	bmp2	TGF_BETA_2 domain-containing protein. (398 aa)
	cthrc1-2	Uncharacterized protein. (235 aa)
	snai2	Uncharacterized protein. (266 aa)
	bmp6	TGF_BETA_2 domain-containing protein. (448 aa)
	gli3-2	Uncharacterized protein. (1568 aa)
	Dlx5.L	Homeobox domain-containing protein. (298 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	cthrc1	Uncharacterized protein. (235 aa)
	Bmp6.S	TGF_BETA_2 domain-containing protein. (448 aa)
	gli3	Uncharacterized protein. (1565 aa)
	dlx5	Homeobox domain-containing protein. (297 aa)
	A0A1L8FQM4	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
	A0A1L8FQD6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
	Epha2.L	Uncharacterized protein. (948 aa)
	gdf10	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (443 aa)
	G50	Uncharacterized protein. (980 aa)
	A0A1L8FD24	Uncharacterized protein. (1045 aa)
	A0A1L8FCC1	MADS-box domain-containing protein. (748 aa)
	adar	Uncharacterized protein. (1291 aa)
	Sox8.L	HMG box domain-containing protein. (459 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1054 aa)
	ihh-2	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (409 aa)
	igfbp5-2	Uncharacterized protein. (265 aa)
	Bmp3.L	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (458 aa)
	Sirt7.L	Deacetylase sirtuin-type domain-containing protein. (393 aa)
	A0A1L8ESG7	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	sox8	HMG box domain-containing protein. (461 aa)
	A0A1L8EPT8	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (144 aa)
	Bmpr2.S	Uncharacterized protein. (383 aa)
	A0A1L8EPQ9	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (130 aa)
	A0A1L8EPQ2	Uncharacterized protein. (181 aa)
	ihh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (409 aa)
	A0A1L8ELB6	Uncharacterized protein. (261 aa)
	A0A1L8EL97	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (315 aa)
	tp53inp2	Uncharacterized protein. (223 aa)
	jund	BZIP domain-containing protein. (300 aa)
	tmem119-2	Uncharacterized protein. (292 aa)
	A0A310TLS9	Uncharacterized protein. (204 aa)
	Tp53inp2.S	Uncharacterized protein. (225 aa)
	A0A310U122	A to I editase domain-containing protein. (118 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	nog	Noggin; Belongs to the noggin family. (222 aa)
	mef2d	SRF-related protein (Clone SL-1). (498 aa)
	BGP	Osteocalcin; Binds strongly to apatite and calcium. (101 aa)
	mapk14	Mitogen-activated protein kinase. (361 aa)
	LOC397711	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
	nog2	Noggin; Belongs to the noggin family. (218 aa)
	nog2-2	Noggin; Belongs to the noggin family. (218 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	ctnnb1-2	Ctnnb1-prov protein. (781 aa)
	snai2-2	Zinc finger transcription factor slug beta. (266 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	A0A1L8HV56	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	A0A1L8HUK7	Mothers against decapentaplegic homolog. (422 aa)
	hand2	BHLH domain-containing protein. (210 aa)
	tmem119	Uncharacterized protein. (292 aa)
	Jund.S	BZIP domain-containing protein. (300 aa)
	bmp3	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (458 aa)
	A0A1L8HME1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	A0A1L8HLI5	BHLH domain-containing protein. (272 aa)
	Gli1.L	Uncharacterized protein. (1362 aa)
	dhh-2	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
	nf1	Uncharacterized protein. (2759 aa)
	A0A1L8HF98	Uncharacterized protein. (119 aa)
	gli1	Uncharacterized protein. (1361 aa)
	dhh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (398 aa)
	Nf1.S	Uncharacterized protein. (2774 aa)
	A0A1L8H6D3	Uncharacterized protein. (116 aa)
	Junb.L	BZIP domain-containing protein. (306 aa)
	Smo.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
	ucma-2	Uncharacterized protein. (138 aa)
	P38-beta	Mitogen-activated protein kinase. (401 aa)
	msx2-2	Homeobox domain-containing protein. (257 aa)
	msx2	Homeobox domain-containing protein. (257 aa)
	Mapk11.S	Mitogen-activated protein kinase. (361 aa)
	ucma	Uncharacterized protein. (138 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EL97	Lrp5.L	A0A1L8EL97	A0A1L8GJX4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.644
A0A1L8EL97	ctnnb1	A0A1L8EL97	Q63ZT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Beta-catenin protein.	0.471
A0A1L8EL97	ctnnb1-2	A0A1L8EL97	Q7ZX35	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Ctnnb1-prov protein.	0.471
A0A1L8ELB6	Shh.L	A0A1L8ELB6	A0A1L8FV87	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.428
A0A1L8ELB6	Sox8.L	A0A1L8ELB6	A0A1L8EYP0	Uncharacterized protein.	HMG box domain-containing protein.	0.449
A0A1L8ELB6	bmp4	A0A1L8ELB6	B7ZPR8	Uncharacterized protein.	Bone morphogenetic protein 4.	0.429
A0A1L8ELB6	bmp4-2	A0A1L8ELB6	Q91703	Uncharacterized protein.	Bone morphogenetic protein 4.	0.429
A0A1L8ELB6	ctnnb1	A0A1L8ELB6	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.509
A0A1L8ELB6	sox8	A0A1L8ELB6	A0A1L8ER49	Uncharacterized protein.	HMG box domain-containing protein.	0.449
A0A1L8EPQ2	A0A1L8HME1	A0A1L8EPQ2	A0A1L8HME1	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.653
A0A1L8EPQ2	A0A1L8HUK7	A0A1L8EPQ2	A0A1L8HUK7	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.713
A0A1L8EPQ2	A0A1L8HV56	A0A1L8EPQ2	A0A1L8HV56	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.653
A0A1L8EPQ2	Bmp2.L	A0A1L8EPQ2	A0A1L8G5P4	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.639
A0A1L8EPQ2	Bmp6.S	A0A1L8EPQ2	A0A1L8FS81	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.500
A0A1L8EPQ2	LOC397711	A0A1L8EPQ2	O42338	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.653
A0A1L8EPQ2	bmp2	A0A1L8EPQ2	A0A1L8G1N2	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.639
A0A1L8EPQ2	bmp4	A0A1L8EPQ2	B7ZPR8	Uncharacterized protein.	Bone morphogenetic protein 4.	0.639
A0A1L8EPQ2	bmp4-2	A0A1L8EPQ2	Q91703	Uncharacterized protein.	Bone morphogenetic protein 4.	0.639
A0A1L8EPQ2	bmp6	A0A1L8EPQ2	A0A1L8FXW8	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.500
A0A1L8EPQ9	A0A1L8HME1	A0A1L8EPQ9	A0A1L8HME1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.653