97 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tm2d2	TM2 domain-containing protein. (198 aa)
	tcim	TC1 domain-containing protein. (96 aa)
	A0A1L8GS57	Tetraspanin. (314 aa)
	A0A1L8GSB4	Protein kinase domain-containing protein. (1256 aa)
	A0A1L8GT16	Uncharacterized protein. (643 aa)
	A0A1L8H0D0	Uncharacterized protein. (749 aa)
	A0A1L8H1F9	Protein kinase domain-containing protein. (1087 aa)
	A0A1L8H1G7	Tetraspanin. (312 aa)
	tcim-2	TC1 domain-containing protein. (96 aa)
	Tm2d2.L	TM2 domain-containing protein. (198 aa)
	A0A1L8H508	Uncharacterized protein. (135 aa)
	Poglut1.L	CAP10 domain-containing protein. (154 aa)
	A0A1L8H5Q9	CAP10 domain-containing protein. (234 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	postn	Uncharacterized protein. (1017 aa)
	A0A1L8HBZ5	CAP10 domain-containing protein. (298 aa)
	A0A1L8HH29	DUF4477 domain-containing protein. (539 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Postn.L	Uncharacterized protein. (1183 aa)
	gsx2	Homeobox domain-containing protein. (244 aa)
	Prag1.S	Protein kinase domain-containing protein. (1282 aa)
	A0A1L8HN14	Protein kinase domain-containing protein. (1122 aa)
	A0A1L8HPJ2	ZnMc domain-containing protein. (581 aa)
	rita1	Uncharacterized protein. (242 aa)
	gsx2-2	Homeobox domain-containing protein. (248 aa)
	Tspan5.L	Tetraspanin. (268 aa)
	prag1	Protein kinase domain-containing protein. (1300 aa)
	A0A1L8HW68	Protein kinase domain-containing protein. (903 aa)
	yjefn3	YjeF N-terminal domain-containing protein. (253 aa)
	rita1-2	Uncharacterized protein. (239 aa)
	A0A1L8I2B6	Uncharacterized protein. (868 aa)
	LOC397855	Beta-1,3-N-acetylglucosaminyltransferase. (375 aa)
	mespa	BHLH transcription factor mespa. (283 aa)
	X-Delta-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa)
	mmp14	Membrane type-1 matrix metalloproteinase 14. (575 aa)
	arrdc1-2	MGC82619 protein. (425 aa)
	dlx2-2	MGC80142 protein. (279 aa)
	tspan14	Tetraspanin. (270 aa)
	synj2bp-2	Outer membrane protein 25. (145 aa)
	tspan15-2	Tetraspanin. (297 aa)
	Nov.L	Uncharacterized protein. (343 aa)
	hif1an	MGC84481 protein. (352 aa)
	tspan5	Tetraspanin. (268 aa)
	neurl1-2	Neuralized. (555 aa)
	dll1-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
	A0A1L8EKH9	STAT_int domain-containing protein. (635 aa)
	Slc35c2.S	TPT domain-containing protein. (351 aa)
	llgl2	WD_REPEATS_REGION domain-containing protein. (1019 aa)
	A0A1L8EP74	Homeobox domain-containing protein. (251 aa)
	tspear	LAM_G_DOMAIN domain-containing protein. (675 aa)
	Llgl1.S	WD_REPEATS_REGION domain-containing protein. (999 aa)
	Stat3.2.L	Signal transducer and activator of transcription. (760 aa)
	Pofut1.L	Uncharacterized protein. (380 aa)
	stat3.1	Signal transducer and activator of transcription. (769 aa)
	rfng	Beta-1,3-N-acetylglucosaminyltransferase. (364 aa)
	A0A1L8ETX3	TPT domain-containing protein. (319 aa)
	Llgl2.L	WD_REPEATS_REGION domain-containing protein. (1017 aa)
	dlx2	Homeobox domain-containing protein. (285 aa)
	A0A1L8EWE8	Homeobox domain-containing protein. (251 aa)
	A0A1L8EWU2	LAM_G_DOMAIN domain-containing protein. (643 aa)
	Lfng.L	Beta-1,3-N-acetylglucosaminyltransferase. (373 aa)
	A0A1L8EYQ3	LLGL domain-containing protein. (1049 aa)
	Nfkbia.S	ANK_REP_REGION domain-containing protein. (312 aa)
	synj2bp	PDZ domain-containing protein. (143 aa)
	jag2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1223 aa)
	Dlk1.S	Uncharacterized protein. (372 aa)
	A0A1L8F0V0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (650 aa)
	tspan15	Tetraspanin. (297 aa)
	nrarp	ANK_REP_REGION domain-containing protein. (114 aa)
	arrdc1	Arrestin_C domain-containing protein. (425 aa)
	Dlk1.L	Uncharacterized protein. (382 aa)
	jag2-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1227 aa)
	Nfkbia.L	ANK_REP_REGION domain-containing protein. (315 aa)
	dll4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (675 aa)
	chac1	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (212 aa)
	neurl1	Uncharacterized protein. (555 aa)
	Hif1an.L	JmjC domain-containing protein. (350 aa)
	galnt11	Polypeptide N-acetylgalactosaminyltransferase. (603 aa)
	ccn3	Uncharacterized protein. (345 aa)
	Galnt11.L	Polypeptide N-acetylgalactosaminyltransferase. (643 aa)
	Fkbp14.L	Peptidylprolyl isomerase. (207 aa)
	jag1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1206 aa)
	dlk2	Uncharacterized protein. (418 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	dll1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
	tp63	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (637 aa)
	pdcd10	Uncharacterized protein. (212 aa)
	A0A1L8G5B3	PID domain-containing protein. (180 aa)
	tgfb2-2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	dlk2-2	Uncharacterized protein. (413 aa)
	Jag1.L	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
	tp63-2	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (636 aa)
	pdcd10-2	Uncharacterized protein. (212 aa)
	slc35c1	TPT domain-containing protein. (363 aa)
	gas2	Uncharacterized protein. (316 aa)
	gas2-2	Uncharacterized protein. (316 aa)
	slc35c1-2	TPT domain-containing protein. (364 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKH9	A0A1L8I2B6	A0A1L8EKH9	A0A1L8I2B6	STAT_int domain-containing protein.	Uncharacterized protein.	0.703
A0A1L8EP74	dlx2	A0A1L8EP74	A0A1L8EW85	Homeobox domain-containing protein.	Homeobox domain-containing protein.	0.666
A0A1L8EP74	dlx2-2	A0A1L8EP74	Q6DD47	Homeobox domain-containing protein.	MGC80142 protein.	0.666
A0A1L8EWE8	dlx2	A0A1L8EWE8	A0A1L8EW85	Homeobox domain-containing protein.	Homeobox domain-containing protein.	0.666
A0A1L8EWE8	dlx2-2	A0A1L8EWE8	Q6DD47	Homeobox domain-containing protein.	MGC80142 protein.	0.666
A0A1L8EYQ3	Llgl2.L	A0A1L8EYQ3	A0A1L8EUD8	LLGL domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.733
A0A1L8EYQ3	llgl2	A0A1L8EYQ3	A0A1L8EMV4	LLGL domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.733
A0A1L8F0V0	A0A1L8GT16	A0A1L8F0V0	A0A1L8GT16	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.517
A0A1L8F0V0	A0A1L8H0D0	A0A1L8F0V0	A0A1L8H0D0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.517
A0A1L8F0V0	dll4	A0A1L8F0V0	A0A1L8FB19	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.411
A0A1L8G5B3	pdcd10	A0A1L8G5B3	A0A1L8G491	PID domain-containing protein.	Uncharacterized protein.	0.568
A0A1L8G5B3	pdcd10-2	A0A1L8G5B3	A0A1L8GA63	PID domain-containing protein.	Uncharacterized protein.	0.568
A0A1L8GS57	A0A1L8GT16	A0A1L8GS57	A0A1L8GT16	Tetraspanin.	Uncharacterized protein.	0.412
A0A1L8GS57	A0A1L8H0D0	A0A1L8GS57	A0A1L8H0D0	Tetraspanin.	Uncharacterized protein.	0.412
A0A1L8GT16	A0A1L8F0V0	A0A1L8GT16	A0A1L8F0V0	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.517
A0A1L8GT16	A0A1L8GS57	A0A1L8GT16	A0A1L8GS57	Uncharacterized protein.	Tetraspanin.	0.412
A0A1L8GT16	A0A1L8H1G7	A0A1L8GT16	A0A1L8H1G7	Uncharacterized protein.	Tetraspanin.	0.412
A0A1L8GT16	Jag1.L	A0A1L8GT16	A0A1L8G723	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.425
A0A1L8GT16	Tspan5.L	A0A1L8GT16	A0A1L8HVC5	Uncharacterized protein.	Tetraspanin.	0.569
A0A1L8GT16	X-Delta-2	A0A1L8GT16	P79941	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.517