50 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8HGJ5	Rho-GAP domain-containing protein. (796 aa)
	A0A1L8EN81	TFCD_C domain-containing protein. (997 aa)
	tbcd	TFCD_C domain-containing protein. (1187 aa)
	A0A1L8F2J9	DUF4683 domain-containing protein. (1416 aa)
	A0A1L8F4B9	Uncharacterized protein. (1020 aa)
	nexmif	DUF4683 domain-containing protein. (1425 aa)
	Thbs2.L	Uncharacterized protein. (1176 aa)
	A0A1L8FG21	Uncharacterized protein. (232 aa)
	ajap1	AJAP1_PANP_C domain-containing protein. (391 aa)
	ajap1-2	AJAP1_PANP_C domain-containing protein. (391 aa)
	rcc2	Uncharacterized protein. (513 aa)
	jag1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1206 aa)
	angpt2	Fibrinogen C-terminal domain-containing protein. (498 aa)
	A0A1L8G5B3	PID domain-containing protein. (180 aa)
	Jag1.L	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
	A0A1L8G9L4	Fibrinogen C-terminal domain-containing protein. (229 aa)
	A0A1L8G9X0	Uncharacterized protein. (268 aa)
	Myoc.S	Olfactomedin-like domain-containing protein. (507 aa)
	myoc	Olfactomedin-like domain-containing protein. (515 aa)
	A0A1L8GRT2	HP domain-containing protein. (365 aa)
	sema3e	Sema domain-containing protein; Belongs to the semaphorin family. (769 aa)
	spry4	Uncharacterized protein. (297 aa)
	Fbln1.L	Uncharacterized protein. (534 aa)
	A0A1L8GW21	Uncharacterized protein. (116 aa)
	A0A1L8GW92	Uncharacterized protein. (126 aa)
	spry4-2	Uncharacterized protein. (297 aa)
	dmtn	HP domain-containing protein. (412 aa)
	Serpine1.L	SERPIN domain-containing protein; Belongs to the serpin family. (403 aa)
	Nf1.S	Uncharacterized protein. (2774 aa)
	A0A1L8H8H9	Rho-GAP domain-containing protein. (659 aa)
	sema3e-2	Sema domain-containing protein; Belongs to the semaphorin family. (276 aa)
	Acvrl1.S	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	cask	Uncharacterized protein; Belongs to the MAGUK family. (920 aa)
	Bcas3.L	BCAS3 domain-containing protein. (812 aa)
	nf1	Uncharacterized protein. (2759 aa)
	acvrl1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	A0A1L8HJF4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (456 aa)
	ap1ar	Uncharacterized protein. (290 aa)
	Efna5.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (185 aa)
	rasa1	Uncharacterized protein. (944 aa)
	ap1ar-2	Uncharacterized protein. (291 aa)
	acer2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	Rasa1.L	Uncharacterized protein. (939 aa)
	Efna5.L	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (185 aa)
	A0A310U3K1	Uncharacterized protein. (113 aa)
	acer2-2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	cask-2	Cask-prov protein; Belongs to the MAGUK family. (920 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F4B9	Serpine1.L	A0A1L8F4B9	A0A1L8H381	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.502
A0A1L8G9L4	Thbs2.L	A0A1L8G9L4	A0A1L8FB81	Fibrinogen C-terminal domain-containing protein.	Uncharacterized protein.	0.430
A0A1L8HJF4	Wnt1.L	A0A1L8HJF4	A0A1L8HHR8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.863
A0A1L8HJF4	wnt1	A0A1L8HJF4	A0A1L8H9S8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.863
Acvrl1.S	acvrl1	A0A1L8H9E4	A0A1L8HHN2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.900
Fzd4.S	Wnt1.L	A0A1L8HB90	A0A1L8HHR8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.942
Fzd4.S	wnt1	A0A1L8HB90	A0A1L8H9S8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.942
Jag1.L	Wnt1.L	A0A1L8G723	A0A1L8HHR8	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.426
Jag1.L	jag1	A0A1L8G723	A0A1L8G0P5	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.900
Jag1.L	wnt1	A0A1L8G723	A0A1L8H9S8	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.411
Nf1.S	Rasa1.L	A0A1L8H8D7	A0A1L8I1U3	Uncharacterized protein.	Uncharacterized protein.	0.708
Nf1.S	nf1	A0A1L8H8D7	A0A1L8HGF2	Uncharacterized protein.	Uncharacterized protein.	0.900
Nf1.S	rasa1	A0A1L8H8D7	A0A1L8HRB9	Uncharacterized protein.	Uncharacterized protein.	0.708
Rasa1.L	Nf1.S	A0A1L8I1U3	A0A1L8H8D7	Uncharacterized protein.	Uncharacterized protein.	0.708
Rasa1.L	acvrl1	A0A1L8I1U3	A0A1L8HHN2	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.514
Rasa1.L	nf1	A0A1L8I1U3	A0A1L8HGF2	Uncharacterized protein.	Uncharacterized protein.	0.708
Rasa1.L	rasa1	A0A1L8I1U3	A0A1L8HRB9	Uncharacterized protein.	Uncharacterized protein.	0.900
Serpine1.L	A0A1L8F4B9	A0A1L8H381	A0A1L8F4B9	SERPIN domain-containing protein; Belongs to the serpin family.	Uncharacterized protein.	0.502
Serpine1.L	Thbs2.L	A0A1L8H381	A0A1L8FB81	SERPIN domain-containing protein; Belongs to the serpin family.	Uncharacterized protein.	0.578
Thbs2.L	A0A1L8G9L4	A0A1L8FB81	A0A1L8G9L4	Uncharacterized protein.	Fibrinogen C-terminal domain-containing protein.	0.430